Dr. Marcos Roberto de Oliveira

Dr. Marcos Roberto de Oliveira

Professor
Federal University of Mato Grossol, Brazil


Highest Degree
Ph.D. in Biochemistry from Universidade Federal do Rio Grande do Sul, Brazil

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Area of Interest:

Biomedical Sciences
100%
Brain Research
62%
Biochemistry
90%
Neurochemical Research
75%
Medicinal Food
55%

Selected Publications

  1. De Oliveira, M.R., N. Elangovan, M. Ljubkovic and A. Baranova, 2014. The roads to mitochondrial dysfunction. J. Biomed. Biotechnol., Vol. 2014. 10.1155/2015/235370.
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  2. De Oliveira, M.R., R.F. da Rocha, M.A.B. Pasquali and J.C.F. Moreira, 2012. The effects of vitamin A supplementation for 3 months on adult rat nigrostriatal axis: Increased monoamine oxidase enzyme activity, mitochondrial redox dysfunction, increased β-amyloid1-40 peptide and TNF-α contents and susceptibility of mitochondria to an in vitro H2O2 challenge. Brain Res. Bull., 87: 432-444.
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  3. De Oliveira, M.R., R.F. da Rocha, C.E. Schnorr and J.C.F. Moreira, 2012. L-NAME cotreatment did prevent neither mitochondrial impairment nor behavioral abnormalities in adult Wistar rats treated with vitamin A supplementation. Fundamen. Clin. Pharmacol., 26: 513-529.
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  4. De Oliveira, M.R., R.F. da Rocha and J.C.F. Moreira, 2012. Increased susceptibility of mitochondria isolated from frontal cortex and hippocampus of vitamin A-treated rats to non-aggregated amyloid-β peptides 1-40 and 1-42. Acta Neuropsychiatrica, 24: 101-108.
  5. De Bittencourt Pasquali, M.A., M.R. Oliveira, M.A. De Bastiani, R.F. Rocha and C.E. Schnorr et al., 2012. L-NAME co-treatment prevent oxidative damage in the lung of adult Wistar rats treated with vitamin A supplementation. Cell Biochem. Funct., 30: 256-263.
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  6. Jardim, F.R., G.H. Zanchettin, A. Dall'Agnol and M.R. De Oliveira, 2011. Como estao relacionados disturbios neurodegenerativos, destino celular e ambiente? Uma abordagem bioquimica [How are related disorders neurodegenerative, destination cell and environment? A biochemical approach]. Destaques Academicos, 3: 81-88.
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  7. De Oliveira, M.R., R.F. da Rocha, L. Stertz, G.R. Fries, D.L. de Oliveira, F. Kapczinski and J.C.F. Moreira, 2011. Total and mitochondrial nitrosative stress, Decreased Brain-Derived Neurotrophic Factor (BDNF) levels and glutamate uptake and evidence of endoplasmic reticulum stress in the hippocampus of vitamin A-treated rats. Neurochem. Res., 36: 506-517.
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  8. De Oliveira, M.R., R. Lorenzi, C.E. Schnorr, M. Morrone and J.C.F. Moreira, 2011. Increased 3-nitrotyrosine levels in mitochondrial membranes and impaired respiratory chain activity in brain regions of adult female rats submitted to daily vitamin A supplementation for 2 months. Brain Res. Bull., 86: 246-253.
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  9. Andrades, M., C. Ritter, M.R. de Oliveira, E.L. Streck, J.C.F. Moreira and F. Dal-Pizzol, 2011. Antioxidant treatment reverses organ failure in rat model of sepsis: Role of antioxidant enzymes imbalance, neutrophil infiltration and oxidative stress. J. Surg. Res., 167: e307-e313.
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  10. Oliveira, M.W., J.B. Minotto, M.R. de Oliveira, A. Zanotto-Filho and G.A. Behr et al., 2010. Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species. Pharmacol. Rep., 62: 185-193.
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  11. De Oliveira, M.R., M.W.S. Oliveira and J.C.F Moreira, 2010. Pharmacological doses of vitamin A increase caspase-3 activity selectively in cerebral cortex. Fundam. Clin. Pharmacol., 24: 445-450.
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  12. Da Rocha, R.F., M.R. De Oliveira, P. Schonhofen, M.A. De Bastiani and C.E. Schnorr et al., 2010. Vitamin A supplementation for different periods alters rat vascular redox parameters. J. Physiol. Biochem., 66: 351-357.
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  13. Da Rocha, R.F., M.R. De Oliveira, P. Schonhofen, C.E. Schnorr, F. Dal Pizzol and J.C.F. Moreira, 2010. Long-term vitamin A supplementation at therapeutic doses induces Mitochondrial Electrons Transfer Chain (METC) impairment and increased Mitochondrial Membrane-Enriched Fraction (MMEF) 3-nitrotyrosine on rat heart. Free Radical Res., 44: 505-512.
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  14. Da Rocha, R.F., M.R. De Oliveira, M.A. de Bittencourt Pasquali, M.E. Andrades, M.W.S. Oliveira, G.A. Behr and J.C.F. Moreira, 2010. Vascular redox imbalance in rats submitted to chronic exercise. Cell Biochem. Funct., 28: 190-196.
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  15. Andreazza, A.C., M.L. Andersen, T.A. Alvarenga, M.R. De Oliveira and F. Armani et al., 2010. Impairment of the mitochondrial electron transport chain due to sleep deprivation in mice. J. Psychiatric Res., 44: 775-780.
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  16. Reolon, G.K., A. Reinke, M.R. de Oliveira, L.M. Braga and M. Camassola et al., 2009. Alterations in oxidative markers in the cerebellum and peripheral organs in MPS I mice. Cell. Mol. Neurobiol., 29: 443-448.
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  17. Pasquali, M.A.B., D.P. Gelain, M.R. De Oliveira, G.A. Behr and L.L. Motta et al., 2009. Vitamin A supplementation induces oxidative stress and decreases the immunocontent of catalase and superoxide dismutase in rat lungs. Exp. Lung Res., 35: 427-438.
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  18. De Oliveira, M.R., M.W.S. Oliveira, R.F. da Rocha, R. Lorenzi and J.C.F. Moreira, 2009. Short-term vitamin A supplementation at therapeutic doses induces a pro-oxidative state in the hepatic environment and facilitates calcium-ion-induced oxidative stress in rat liver mitochondria independently from permeability transition pore formation. Cell Biol. Toxicol., 25: 545-560.
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  19. De Oliveira, M.R., M.W.S. Oliveira, R.F. da Rocha and J.C.F. Moreira, 2009. Vitamin A supplementation at pharmacological doses induces nitrosative stress on the hypothalamus of adult Wistar rats. Chemico-Biol. Interact., 180: 407-413.
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  20. De Oliveira, M.R., M.W.S. Oliveira, M.L.M. Hoff, G.A. Behr, R.F. da Rocha and J.C.F. Moreira, 2009. Evaluation of redox and bioenergetics states in the liver of vitamin A-treated rats. Eur. J. Pharmacol., 610: 99-105.
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  21. De Oliveira, M.R., M.W.S. Oliveira, G.A. Behr, M.L.M. Hoff, R.F. da Rocha and J.C.F. Moreira, 2009. Evaluation of the effects of vitamin A supplementation on adult rat Substantia nigra and Striatum redox and bioenergetic states: Mitochondrial impairment, increased 3-nitrotyrosine and α-synuclein, but decreased D2 receptor contents. Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 33: 353-362.
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  22. De Oliveira, M.R., M.W.S. Oliveira, G.A. Behr, M.A. de Bittencourt Pasquali and J.C.F. Moreira, 2009. Increased receptor for advanced glycation endproducts immunocontent in the cerebral cortex of vitamin A-treated rats. Neurochem. Res., 34: 1410-1416.
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  23. De Oliveira, M.R., M.W.S. Oliveira, G.A. Behr and J.C.F. Moreira, 2009. Vitamin A supplementation at clinical doses induces a dysfunction in the redox and bioenergetics states, but did change neither caspases activities nor TNF-α levels in the frontal cortex of adult Wistar rats. J. Psychiatric Res., 43: 754-762.
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  24. De Bittencourt Pasquali, M.A., D.P. Gelain, M.R. De Oliveira, G.A. Behr and L.L. da Motta et al., 2009. Vitamin A supplementation for different periods alters oxidative parameters in lungs of rats. J. Med. Food, 12: 1375-1380.
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  25. Behr, G.A., L.L. da Motta, M.R. De Oliveira, M.W.S. Oliveira, M.L.M. Hoff, R.B. Silvestrin and J.C.F. Moreira, 2009. Decreased anxiety-like behavior and locomotor/exploratory activity and modulation in hypothalamus, hippocampus and frontal cortex redox profile in sexually receptive female rats after short-term exposure to male chemical cues. Behav. Brain Res., 199: 263-270.
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  26. Behr, G.A., L.L. da Motta, M.R. De Oliveira, M.W.S. Oliveira, D.P. Gelain and J.C.F. Moreira, 2009. Modulation in reproductive tissue redox profile in sexually receptive female rats after short-term exposure to male chemical cues. Chem. Senses, 34: 317-323.
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  27. De Oliveira, M.R., R.B. Silvestrin, T. Mello e Souza and J.C.F. Moreira, 2008. Therapeutic vitamin A doses increase the levels of markers of oxidative insult in Substantia nigra and decrease locomotory and exploratory activity in rats after acute and chronic supplementation. Neurochem. Res., 33: 378-383.
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  28. De Oliveira, M.R. and J.C.F. Moreira, 2008. Impaired redox state and respiratory chain enzyme activities in the cerebellum of vitamin A-treated rats. Toxicology, 253: 125-130.
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  29. Dani, C., M.A. Pasquali, M.R. Oliveira, F.M. Umezu, M. Salvador, J.A. Henriques and J.C. Moreira, 2008. Protective effects of purple grape juice on carbon tetrachloride-induced oxidative stress in brains of adult Wistar rats. J. Med. Foods, 11: 55-61.
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  30. Dani, C., L.S. Oliboni, M.A.B. Pasquali, M.R. De Oliveira and F.M. Umezu et al., 2008. Intake of purple grape juice as a hepatoprotective agent in Wistar rats. J. Med. Food, 11: 127-132.
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  31. Rudnicki, M., M.R. De Oliveira, T.D. Veigapereira, F.H. Reginatto, F. Dal-Pizzol and J.C.F. Moreira, 2007. Antioxidant and antiglycation properties of Passiflora alata and Passiflora edulis extracts. Food Chem., 100: 719-724.
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  32. Rudnicki, M., M.M. Silveira, T.V. Pereira, M.R. Oliveira, F.H. Reginatto, F. Dal-Pizzol and J.C.F. Moreira, 2007. Protective effects of Passiflora alata extract pretreatment on carbon tetrachloride induced oxidative damage in rats. Food Chem. Toxicol., 45: 656-661.
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  33. De Oliveira, M.R., R.B. Silvestrin, T.M. Souza and J.C.F. Moreira, 2007. Oxidative stress in the hippocampus, anxiety-like behavior and decreased locomotory and exploratory activity of adult rats: Effect of sub acute vitamin A supplementation at therapeutic doses. Neuro Toxicol., 28: 1191-1199.
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  34. De Oliveira, M.R., M.A. de Bittencourt Pasquali, R.B. Silvestrin, T. Mello e Souza and J.C.F. Moreira, 2007. Vitamin A supplementation induces a prooxidative state in the striatum and impairs locomotory and exploratory activity of adult rats. Brain Res., 1169: 112-119.
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  35. De Oliveira, M.R. and J.C.F. Moreira, 2007. Acute and chronic vitamin A supplementation at therapeutic doses induces oxidative stress in submitochondrial particles isolated from cerebral cortex and cerebellum of adult rats. Toxicol. Lett., 173: 145-150.
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  36. Benetti, M.R.N., M. Rudnicki, A. Zanotto-Filho, M.R. De Oliveira and A.G. Kurek et al., 2007. Evaluation of antioxidant effect of extracts of Symphyopappus casarettoi. Fitoterapia, 78: 232-234.
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  37. Pinho, R.A., M.E. Andrades, M.R. De Oliveira, A.C. Pirola and M.S. Zago et al., 2006. Imbalance in SOD/CAT activities in rat skeletal muscles submitted to treadmill training exercise. Cell Biol. Int., 30: 848-853.
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  38. Da Frota Jr., M.L.C., E.G. da Silva, G.A. Behr, M.R. De Oliveira, F. Dal-Pizzol, F. Klamt and J.C.F. Moreira, 2006. All-trans retinoic acid induces free radical generation and modulate antioxidant enzyme activities in rat sertoli cells. Mol. Cell. Biochem., 285: 173-179.
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  39. Paula, M.M., C.T. Pich, F. Petronilho, L.B. Drei and M. Rudnicki et al., 2005. Antioxidant activity of new ruthenium compounds. Redox Rep., 10: 139-143.
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  40. Klamt, F., M.R. De Oliveira and J.C.F. Moreira, 2005. Retinol induces permeability transition and cytochrome c release from rat liver mitochondria. Biochimica Biophysica Acta (BBA)-Gen. Subj., 1726: 14-20.
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