Prof. Dr. Yahdiana  Harahap

Prof. Dr. Yahdiana Harahap

Professor
Universitas Indonesia, Indonesia


Highest Degree
Ph.D. in Pharmacy from Institut Teknologi Bandung, Bandung, Indonesia

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Area of Interest:

Chemistry
100%
Pharmaceutical Chemistry
62%
Bioequivalence Study
90%
Carcinogenesis
75%
Bioanalysis
55%

Selected Publications

  1. Prasaja, B., Y. Harahap, W. Lusthom, T. Sinandang, L.Y. Yusvita, D. Puspita and T. Anggun, 2019. Comparative bioavailaibilty of two valproic acid delayed-release tablets in healthy volunteers with tighter acceptance criteria to anticipate breakthrough seizures. Pharm. Sci. Asia, 46: 12-18.
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  2. Prasaja, B., Y. Harahap, W. Lusthom, A. Sofiana, F. Safira, M. Sandra and G. Puspanegara, 2019. Study on bioequivalence of beraprost in healthy volunteers by liquid chromatography with tandem mass spectrometry. Biomed. Chromatogr., Vol. 33. 10.1002/bmc.4403.
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  3. Yantih, N., Y. Harahap, R. Setiabudy and W. Sumaryono, 2018. Pilot study of isoniazid acetylation in melanesian healthy subject from Indonesia. J. Young Pharm., 10: s140-s144.
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  4. Supandi, S., Y. Harahap, H. Harmita and R. Andalusia, 2018. Simultaneous analysis of 6-mercaptopurine, 6-methylmercaptopurine, and 6-thioguanosine-5’-monophosphate in dried blood spot using ultra performance liquid chromatography tandem mass spectrometry. Indonesian J. Chem., 18: 544-551.
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  5. Supandi, S., Y. Harahap, H. Harmita and R. Andalusia, 2018. Quantification of 6-mercaptopurine and its metabolites in patients with acute lympoblastic leukemia using dried blood spots and UPLC-MS/MS. Sci. Pharm., Vol. 86. 10.3390/scipharm86020018.
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  6. Ramadon, D., E. Anwar and Y. Harahap, 2018. In vitro Penetration and bioavailability of novel transdermal quercetin-loaded ethosomal gel. Indian J. Pharma. Sci., 79: 948-956.
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  7. Rahayu, S.T., Y. Harahap, A. Munim and N. Sutandyo, 2018. Determination of tamoxifen and 4-hydroxytamoxifen levels in rat plasma after administration of the ethyl acetate fraction of myrmecodia erinaceae becc. using liquid chromatography tandem mass-spectrometry. Int. J. Pharmacol., 14: 215-223.
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  8. Prasaja, B., Y. Harahap, W. Lusthom, L. Yumi, A. Sofiana, M. Sandra and U. Chilmi, 2018. Impact of truncated area on point estimate and intra-subject variability in bioequivalence of dutasteride with long half-life. Drug Res., 68: 238-240.
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  9. Harahap, Y., N. Atikafaza, Erwin, R. Andalusia, 2018. Analysis of 4-hydroxy-n-desmethyltamoxifen and tamoxifen in dried blood spot of breast cancer patients by liquid chromatography-tandem mass spectrometry. J. Global Pharma. Technol., 10: 14-20.
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  10. Harahap, Y., N. Andriyani and Harmita, 2018. Method development and validation of lercanidipine in human plasma by liquid chromatography tandem mass spectrometry. Int. J. Appl. Pharm., 10: 87-91.
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  11. Harahap, Y., G.A. Amalia and B.P. Maggadani, 2018. Analysis of rifampicin in dried blood spots using high performance liquid chromatography. Asian J. Sci. Res., 11: 232-239.
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  12. Harahap, Y., F. Alkindy and G. Ashiila, 2018. Analysis of rifampicin in dried blood spot of tuberculosis patients for therapeutic drug monitoring using high performance liquid chromatography. J. Young Pharm., 10: 48-51.
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  13. Harahap, Y., B. Prasaja, W. Lusthom, L.Y. Yusvita and T. Sinandang, 2018. A bioequivalence study of quetiapine 25 mg film-coated tablets in healthy Indonesian subjects. Int. J. Clin. Pharmacol. Ther., 56: 38-42.
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  14. Yantih, N., Y. Harahap, W. Sumaryono, R. Setiabudy and L. Rahayu, 2017. Hepatoprotective activity of pineapple (Ananas comosus) juice on isoniazid induced rats. J. Biol. Sci., 17: 388-393.
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  15. Supandi, S., Y. Harahap, H. Harmita, R. Andalusia, M. Ika and N. Azizah, 2017. Simultaneous analytical method of 6-mercaptopurine and 6-methylmercaptopurine in vitro study with bio-sampling venipuncture and dried blood spot. J. Glob. Pharma. Technol., 5: 77-84.
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  16. Supandi, S., Harahap, Y., R.A. Harmita and M. Ika, 2017. Analysis of 6-mercaptopurine and 6-methylmercaptopurine in dried blood spots using liquid chromatography-tandem mass spectrometry and its application in childhood acute lymphoblastic leukemia patients. Asian J. Pharm. Clin. Res., 10: 120-125.
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  17. Oktaviani, R.M., S.P. Sari and Y. Harahap, 2017. Effect of 70% ethanol extract of orthosiphonis stamineus benth leaves on the pharmacokinetic parameters of furosemide in male white rats. Int. J. Appl. Pharm., 9: 54-58.
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  18. Hayun, Y.H. and M.O. Puspasari, 2017. Development of a high performance liquid chromatography method for simultaneous analysis of theophylline, guaifenesin and diphenhydramine in an elixir. Trop. J. Pharma. Res., 16: 2501-2506.
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  19. Hayun, H., R. Rahmawati, Y. Harahap and S.P. Sari, 2017. Development of UPLC-MS/MS method for quantitative analysis of curcumin in human plasma. Acta Chromatographica. 10.1556/1326.2017.00153.
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  20. Harahap, Y., N. Azizah and R. Andalusia, 2017. Simultaneous analytical method development of 6-mercaptopurine and 6-methylmercaptopurine in plasma by high performance liquid chromatography-photodiode array. J. Young Pharm., 9: s29-s34.
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  21. Harahap, Y., N. Azizah and R. Andalusia, 2017. Simultaneous analytical method development of 6-mercaptopurine and 6-methylmercaptopurine in plasma by high performance liquid chromatography-photodiode array. J. Young Pharm., 9: S29-S34.
  22. Harahap, Y., 2017. Determination of valproic acid without derivatization in human plasma using high performance liquid chromatography-photodiode array. J. Global Pharm. Technol., 9: 82-89.
  23. Harahap, Y. and A.E. Baskara, 2017. Method validation of esomeprazole analysis in human plasma using high performance liquid chromatography-photodiode array. J. Young Pharm., 9: S24-S28.
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  24. Harahap Y. and I. Maysyarah, 2017. Analytical validation of clopidogrel in human plasma through ultrahigh performance liquid chromatography-tandem mass spectrometry. Int. J. Appl. Pharm., 9: 163-167.
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  25. Prasaja, B., Y. Harahap, W. Lusthom, T. Sinandang and L. Yusvita et al., 2016. Formulation of orally disintegrating tablet of donepezil and its comparative bioavailability in healthy volunteers. J. Int. Res. Med. Pharm. Sci., 8: 158-163.
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  26. Nurmeilis, Y. Harahap, F.C. Saputri, A. Munim and R. Setiabudy, 2016. Determination of irbesartan and sinensetin simultaneously by liquid chromatography tandem mass spectrometry and their application to drug interaction study in rat plasma. Int. J. Pharm. Pharm. Sci., 8: 96-100.
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  27. Meilis, N., Y. Harahap, F.C. Saputri, A. Munim and R. Setiabudy, 2016. Pharmacokinetic interaction between irbesartan and Orthosiphon stamineus extract in rat plasma. Asian J. Pharm. Sci., 11: 70-71.
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  28. Harahap, Y., S. Purnasari, R.R. Harmita, K. Dian, W.S. Pratami and S. Fatriyah, 2016. Quantification of atorvastatin in human plasma by liquid chromatography tandem mass spectrometry and its application for bioequivalence study of three formulations. Asian J. Pharm. Sci., 11: 66-67.
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  29. Harahap, Y., C. Samuel, R. Andalusia and N.F. Syafhan, 2016. Analysis of 4-hydroxycyclophosphamide in cancer patients plasma for therapeutic drug monitoring of cyclophosphamide. Int. J. Pharm. Pharm. Sci., 8: 194-200.
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  30. Harahap, Y., B. Prasaja, F. Azmi, W. Lusthom and T. Sinandang et al., 2015. Bioequivalence study of two rosuvastatin tablet formulations in healthy Indonesian. Int. J. Clin. Pharmacol. Therapeutics .
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  31. Harahap, Y., B. Prasaja and P. Cahyaningsih, 2015. Single-dose bioequivalence of cetirizine-pseudoephedrine extended release tablet formulations assessed in healthy subjects. J. Int. Res. Med. Pharm. Sci., 3: 1-8.
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  32. Harahap, Y., R. Andalusia and Y. Crystalia, 2014. Analysis of O6-methylguanine in cancer patient blood during administration of cyclophosphamide using ultra high performance liquid chromatography-tandem mass spectrometry. J. Adv. Med. Pharm. Sci., 2: 20-28.
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  33. Rahayu, S.T., Y. Harahap and D. Harmita, 2013. Bioanalytical method validation of valproic acid in human plasma in-vitro after derivatization with 2, 4-dibromoacetophenon by high performance liquid chromatography-photo diode array and its application to in-vivo study. Int. J. Pharm. Teach. Practices, 4: 644-648.
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  34. Harahap, Y., M.M. Budi Prasaja, W. Lusthom and A.F. Hardiyanti, 2013. Bioequivalence of trimetazidine modified release tablet formulations assessed in Indonesian subjects. J. Bioequiv Availab, 5: 117-120.
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  35. Harahap, Y., K. Dianpratami, M. Wulandari and R. Rahmawati, 2012. Validation of metformin hydrochloride in human plasma by HPLC-Photo Diode Array (PDA) for application of bioequivalence study. J. Life Sci., 6: 20-27.
  36. Harahap, Y., B. Prasaja, W. Lusthom, G. Hardiyanti, B. Mena and L. Ginting, 2012. A bioequivalence study of two azithromycin tablet formulations in Indonesian healthy subjects. J. Bioequiv Bioavail, 4: 48-51.
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  37. Harahap, Y., 2012. Validation of analytical method of irbesartan plasma in vitro by high performance liquid chromatography-fluorescence. J. Life Sci., 6: 726-731.
  38. Prasaja, B., Y. Harahap, W. Lusthom, E.C. Setiawan and M.B. Ginting, 2011. A bioequivalence study of two tamsulosin sustained-release tablets in Indonesian healthy volunteers. Eur. J. Drug Metabolism Pharm., 36: 109-113.
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  39. Harahap, Y., S. Purnasari, H. Hayun, K. Dianpratami and M. Wulandari, 2011. Bioequivalence study of metformin HCl XR caplet formulations in healthy Indonesian volunteers. J. Bioequiv Bioavail, 3: 16-19.
  40. Prasaja, B., L. Sasongko, Y. Harahap, W. Lusthom and M. Grigg, 2009. Simultaneous quantification of losartan and active metabolite in human plasma by liquid chromatography-tandem mass spectrometry using irbesartan as internal standard. J. Pharm. Biomed. Analysis, 49: 862-867.
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  41. Harahap, Y., L. Sasongko, B. Prasaja, W. Lusthom and E.C. Setiawan, 2009. Comparative bioavailability study of two ramipril tablet formulations in indonesian healthy volunteers. J. Bioanal Biomed., 1: 17-21.
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  42. Harahap, Y., L. Sasongko, B. Prasaja, E. Indriati and W. Lusthom, 2009. Comparative bioavailability of two dexamethasone tablet formulations in Indonesian healthy volunteers. Arzneimittelforschung, 59: 191-194.
  43. Harahap, Y., L. Sasongko, B. Prasaja, E. Indriati, W. Lusthom and L. Lipin, 2008. Comparative bioavailability of two estazolam tablet formulations in Indonesian healthy volunteers. Arzneimittelforschung, 58: 501-504.
  44. Harahap, Y., B. Prasaja, E. Indriati and W. Lusthom, 2008. Comparative bioavailability of two cetirizine tablet formulations in Indonesian healthy volunteers. Int. J. Clin. Pharmacol. Ther., 46: 268-272.
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  45. Harahap, Y., B. Prasaja, E. Indriati and W. Lusthom, 2007. Bioequivalence of ciprofloxacin tablet formulations assessed in Indonesian volunteers. Int. J. Clin. Pharmacol. Ther., 45: 373-376.
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