Dr. Yanjun  Dong
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Dr. Yanjun Dong

Associate Professor
China Agricultural University, China

Highest Degree
Ph.D. in Molecular Sciences from Shanxi Agricultural University, China

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Area of Interest:

Biomedical Sciences
Molecualar Biology
Stem Cell
Tissue Culture

Research Publications in Numbers


Selected Publications

  1. Wang, H., J. Wang, Y. Bai, J. Li, L. Li and Y. Dong, 2016. CD11c+ CD8+ T cells reduce renal fibrosis following ureteric obstruction by inducing fibroblast apoptosis. Int. J. Mol. Sci., Vol. 18. 10.3390/ijms18010001.
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  2. Dong, Y., M. Yang, J. Zhang, X. Peng, J. Cheng, T. Cui and J. Du, 2016. Depletion of CD8+ T cells exacerbates CD4+ T cell-induced monocyte-to-fibroblast transition in renal fibrosis. J. Immunol., 196: 1874-1881.
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  3. Dong, J., Y. Dong, Z. Chen, W.E. Mitch and L. Zhang, 2016. The pathway to muscle fibrosis depends on myostatin stimulating the differentiation of fibro/adipogenic progenitor cells in chronic kidney disease. Kidney Int., 91: 119-128.
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  4. Dong, J., Y. Dong, F. Chen, W.E. Mitch and L. Zhang, 2016. Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues. Int. J. Obesity, 40: 434-442.
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  5. Silva, K.A.S., J. Dong, Y. Dong, Y. Dong and N. Schor et al., 2015. Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexia. J. Biol. Chem., 290: 11177-11187.
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  6. Qiu, S., Z. Xiao, C. Piao, J. Zhang and Y. Dong et al., 2015. AMPKα2 reduces renal epithelial transdifferentiation and inflammation after injury through interaction with CK2β. J. Pathol., 237: 330-342.
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  7. Peng, X., Z. Xiao, J. Zhang, Y. Li, Y. Dong and J. Du, 2015. IL-17A produced by both γδ T and Th17 cells promotes renal fibrosis via RANTES-mediated leukocyte infiltration after renal obstruction. J. Pathol., 235: 79-89.
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  8. Peng, X., J. Zhang, Z. Xiao, Y. Dong and J. Du, 2015. CX3CL1-CX3CR1 interaction increases the population of Ly6C-CX3CR1hi macrophages contributing to unilateral ureteral obstruction-induced fibrosis. J. Immunol., 195: 2797-2805.
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  9. Xiao, Z., J. Zhang, X. Peng, Y. Dong, L. Jia, H. Li and J. Du, 2014. The notch γ-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-β/Smad2/3 signaling pathway activation. Int. J. Biochem. Cell Biol., 55: 65-71.
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  10. Dong, Y., K.A.S. Silva, Y. Dong and L. Zhang, 2014. Glucocorticoids increase adipocytes in muscle by affecting IL-4 regulated FAP activity. Faseb J., 28: 4123-4132.
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  11. Zhang, L., J. Pan, Y. Dong, D.J. Tweardy, Y. Dong, G. Garibotto and W.E. Mitch, 2013. Stat3 activation links a C/EBPδ to myostatin pathway to stimulate loss of muscle mass. Cell Metab., 18: 368-379.
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  12. Thomas, S.S., Y. Dong, L. Zhang and W.E. Mitch, 2013. Signal regulatory protein-α interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease. Kidney Int., 84: 308-316.
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  13. Dong, Y., R. Lakhia, S.S. Thomas, Y. Dong, X.H. Wang, K.A.S. Silva and L. Zhang, 2013. Interactions between p-Akt and Smad3 in injured muscles initiate myogenesis or fibrogenesis. Am. J. Physiol. Endocrinol. Metab., Vol. 305. 10.1152/ajpendo.00644.2012.
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  14. Dong, Y., J.S. Pan and L. Zhang, 2013. Myostatin suppression of akirin1 mediates glucocorticoid-induced satellite cell dysfunction. Plos One, Vol. 8. 10.1371/journal.pone.0058554.
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  15. Zhang, L., Y. Dong, Y. Dong, J. Cheng and J. Du, 2012. Role of integrin-β3 protein in macrophage polarization and regeneration of injured muscle. J. Biol. Chem., 287: 6177-6186.
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  16. Dong, C., H. Wang, L. Xue, Y. Dong and L. Yang et al., 2012. Coat color determination by miR-137 mediated down-regulation of microphthalmia-associated transcription factor in a mouse model. RNA, 18: 1679-1686.
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  17. Wang, H., Y. Dong, W. Chen, J. Hei and C. Dong, 2011. Expression and localization of nerve growth factor (NGF) in the testis of alpaca (llama pacos). Folia Histochem. Cytobiol., 49: 55-61.
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  18. Fan, R., Y. Dong, J. Cao, R. Bai and Z. Zhu et al., 2011. Gene expression profile in white alpaca (Vicugna pacos) skin. Animal, 5: 1157-1161.
  19. Dong, Y., H. Wang, J. Cao, J. Ren and R. Fan et al., 2011. Nitric oxide enhances melanogenesis of alpaca skin melanocytes in vitro by activating the MITF phosphorylation. Mol. Cell. Biochem., 352: 255-260.
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  20. Zhu, Z., J. He, X. Jia, J. Jiang and R. Bai et al., 2010. MicroRNA-25 functions in regulation of pigmentation by targeting the transcription factor MITF in alpaca (Lama pacos) skin melanocytes. Domestic Anim. Endocrinol., 38: 200-209.
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  21. Dong, Y., J. Cao, H. Wang, J. Zhang and Z. Zhu et al., 2010. Nitric oxide enhances the sensitivity of alpaca melanocytes to respond to α-melanocyte-stimulating hormone by up-regulating melanocortin-1 receptor. Biochem. Biophys. Res. Commun., 396: 849-853.
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