Dr. Feng  Xu

Dr. Feng Xu

Professor
Southern Medical University, Fengxian Hospital, China


Highest Degree
PostDoc. in Medicine Biology from Clemson University, USA

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Area of Interest:

Medicine
100%
Tissue Engineering
62%
Renal Medicine
90%
Cancer Biology
75%
Psychiatry
55%

Selected Publications

  1. Zhang, L., P. Xu, Y. Cheng, P. Wang and X. Ma et al., 2019. Diet-induced obese alters the expression and function of hepatic drug-metabolizing enzymes and transporters in rats. Biochem. Pharmacol., 164: 368-376.
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  2. Zhang, L., C. Liang, P. Xu, M. Liu, F. Xu and X. Wang, 2019. Characterization of in vitro Mrp2 transporter model based on intestinal organoids. Regul. Toxicol. Pharmacol., 10.1016/j.yrtph.2019.104449.
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  3. Xu, F. and Y. Ren, 2019. Abnormal tumor-associated molecules expression in both depression patients and chronic stressed mice. FASEB J., Vol. 33. .
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  4. Li, H., T. Li, Y.J. Hsueh, F. Xu and Y.J. Zhang, 2019. Tandem arylation and regioselective allylic etherification of 2,3-allenol via Pd/B cooperative catalysis. Organic Biomol. Chem., 10.1039/C9OB01792E.
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  5. Zhang, Y., D. Zheng, T. Zhou, H. Song and M. Hulsurkar et al., 2018. Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers. Nat. Commun., Vol. 9. 10.1038/s41467-018-06177-2.
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  6. Yang, C., J. Cai, C. Fei and F. Xu, 2018. Setting off firecrackers: An economic way to release inner stress for patients with depression. Perspect. Psychiatric Care, 55: 372-372.
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  7. Xu, F., Y. Ren, C. Yang, Z. Li and Z. Yang et al., 2018. Chronic stress disturbs metabolome of blood plasma and urine in diabetic rats. Front. Psychiatry, Vol. 9. 10.3389/fpsyt.2018.00525.
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  8. Ren, Y. and F. Xu, 2018. How patients should be counseled on adverse drug reactions: Avoiding the nocebo effect. Res. Soc. Adm. Pharm., Vol. 14. 10.1016/j.sapharm.2018.04.007.
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  9. Zhang, L., J. Zhao, C. Liang, M. Liu, F. Xu and X. Wang, 2017. A novel biosensor based on intestinal 3D organoids for detecting the function of BCRP. Drug Deliv., 24: 1453-1459.
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  10. Xu, F., H.M. Wu and T. Zhou, 2017. Sellf-Assembling Rada16-I peptide hydrog elscaffold loaded with tamoxifen for breast reconstruction following lumpectomy. Clin. Ther., 39: e74-e74.
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  11. Wu, H., T. Zhou, L. Tian, Z. Xia and F. Xu, 2017. Self-assembling RADA16-I peptide hydrogel scaffold loaded with tamoxifen for breast reconstruction. BioMed. Res. Int., 10.1155/2017/3656193.
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  12. Wei, H., T. Zhou, B. Tan, L. Zhang, M. Li, Z. Xiao and F. Xu, 2017. Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway. Oncotarget, 8: 44351-44365.
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  13. Li, M., J. Cai, P. Zhang, C. Fei and F. Xu, 2017. Drug brand response and its impact on compliance and efficacy in depression patients. Front. Pharmacol., Vol. 7. 10.3389/fphar.2016.00540.
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  14. Yang, Z., Y. Cheng, T. Zhou and F. Xu, 2016. Excessive human serum albumin might weaken anticancer effect of Cisplatin and Etoposide in vitro study. Int. J. Clin. Exp. Med., 9: 13384-13393.
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  15. Yang, Z., T. Zhou, Y. Cheng, M. Li, X. Tan and F. Xu, 2016. Weakening impact of excessive human serum albumin (eHSA) on cisplatin and etoposide anticancer effect in C57BL/6 mice with tumor and in human NSCLC A549 cells. Front. Pharmacol., Vol. 7. 10.3389/fphar.2016.00434.
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  16. Xia, Z., H. Wei, J. Duan, T. Zhou, Z. Yang and F. Xu, 2016. Chronic unpredicted mild stress-induced depression alter saxagliptin pharmacokinetics and CYP450 activity in GK rats. Peer J., Vol. 4. 10.7717/peerj.1611.
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  17. Duan, J., W. Yue, E. JianYu, J. Malhotra and S.E. Lu et al., 2016. In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis and STAT3 and NFκB signaling in pancreatic cancer cells. Scient. Rep., Vol. 6. 10.1038/srep31672.
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  18. Zhang, Y., Y. Wang, Z. Xiao and F. Xu, 2015. Pharmacists' roles in cancer pain control: A model in developing China. Res. Soc. Administrative Pharm., 3: e144-e145.
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  19. Xia, Z., Z. Xiao, E. Ma and F. Xu, 2015. Impact of mood disorder on medication adherence in patients with chronic diseases at a shanghai rural hospital. Int. J. Pharmacol., 11: 518-522.
  20. Wu, H., H. Wei and F. Xu, 2015. Pharmacist-led nonpharmacological intervention in cancer chemotherapy. Patient Educ. Couns., Vol. 2. 10.1016/j.pec.2014.11.014.
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  21. Wei, H., Y. Zhang and F. Xu, 2015. A minireview on the supportive care in cancer with traditional Chinese medicine. Int. J. Pharmacol., 11: 222-225.
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  22. Wang, Y., H. Wu and F. Xu, 2015. Impact of clinical pharmacy services on KAP and QOL in cancer patients: A single-center experience. BioMed. Res. Int., 10.1155/2015/502431.
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  23. Zeng, Y., X. Xie, J. Duan, T. Zhou, Y. Zhang, M. Yang and F. Xu, 2014. Perturbation of mitiglinide metabolism by chronic unpredicted mild stress in rats. Scient. Rep., Vol. 4. 10.1038/srep03794.
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  24. Xiao, Z. and F. Xu, 2014. Health literacy and medication preference: Why do most patients choose imported brand-name drugs?. Patient Educ. Couns., 1: 155-156.
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  25. Ma, E., M. Fang and F. Xu, 2014. Pharmacist dispense under a doctor–patient tension: How should we deal with this? Eur. J. Hosp. Pharm., 21: 378-378.
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  26. Zhou, T., S. Lu, X. Liu, Y. Zhang and F. Xu, 2013. Review of the rational use and adverse reactions to human serum albumin in the People’s Republic of China. Patient Prefer. Adherence, 7: 1207-1212.
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  27. Zhou, J.M., X.M. Cui, W.B. Zhang and F. XU, 2013. Repair effect of Sanchi-loaded electrospun artificial skin substitute on damaged skin in rats. Res. J. Biotechnol., 8: 6-9.
  28. Zheng, Z., Y. Zeng, H. Huang and F. Xu, 2013. MicroRNA-132 may play a role in coexistence of depression and cardiovascular disease: A hypothesis. Med. Sci. Mon., 19: 438-443.
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  29. Zhang, Y., T. Zhou, J. Duan, Z. Xiao, G. Li and F. Xu, 2013. Inhibition of P-glycoprotein and Glutathione S-transferase-pi mediated resistance by fluoxetine in MCF-7/ADM cells. Biomed. Pharmacother., 67: 757-762.
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  30. Xiao, Z., Z. Li and F. Xu, 2013. Role of the Internet in patient education and counseling: A framework for health-care provider in developing China. Patient Educ. Couns., 3: 411-412.
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  31. Wang, Y., H. Huang, Y. Zeng, J. Wu, R. Wang, B. Ren and F. Xu, 2013. Pharmacist-led medication education in cancer pain control: A multicentre randomized controlled study in Guangzhou, China. J. Int. Med. Res., 41: 1462-1472.
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  32. Li, Z., Z. Xiao, Z. Li, Q. Zhong, Y. Zhang and F. Xu, 2013. 116 cases of neonatal early-onset or late-onset sepsis: A single center retrospective analysis on pathogenic bacteria species distribution and antimicrobial susceptibility. Int. J. Clin. Exp. Med., 6: 693-699.
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  33. Li, Z., Q. Zhong, H. Chang, C. Yang, Z. Xiao and F. Xu, 2013. A non-albicans Candida fungemia in very low birth weight infants in the neonatal intensive care unit of an “AAA” tertiary hospital in Shenzhen, China. Biomed. Res., 24: 435-440.
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  34. Guo, J.W., Z.J. Xiao and F. Xu, 2013. Efficacy of Chinese medicine ShuGanJieYu capsule for functional dyspepsia. Acta Pharmacol. Sinica, 34: 23-23.
  35. Duan, J.J., Y. Zeng, T. Zhou, Y. Zhang and F. Xu, 2013. Study on the pharmacokinetics of tacrolimus in depression model rats. Int. J. Pharmacol., 9: 265-270.
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  36. Cai, J., M. Ye, C. Fei and F. Xu, 2013. Impact of brand-name drug worship and expectation psychology on antidepressant efficacy. Int. J. Clin. Exp. Med., 6: 724-726.
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  37. Zhou, T., J. Duan, Y. Wang, X. Chen and G. Zhou et al., 2012. Fluoxetine synergys with anticancer drugs to overcome multidrug resistance in breast cancer cells. Tumor Biol., 33: 1299-1306.
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  38. Zheng, Z. and F. Xu, 2012. Neuroplasticity may play a role in inter‐individual difference among neuropsychiatric disease treatment efficacy. Dev. Psychobiol., 54: 369-371.
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  39. Xu, F., 2012. Predictive factors associated with gefitinib response in patients with advanced non-small-cell lung cancer (NSCLC). Ann. Oncol., 23: 47-48.
  40. Xiao, Z., Y. Zhang, Y. Wang and F. Xu, 2012. Quality assessment for systematic review /meta-analysis on antidepressant therapy published in Chinese journals. Int. J. Pharmacol., 8: 614-620.
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  41. Guo, J.W., J.M. Chen, L.J. Lin and F. Xu, 2012. Five chemical constituents of the ethyl acetate fraction from ethanol extract of semen litchi. J. Med. Plant Res., 6: 168-170.
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  42. Duan, J.J., T. Zhou, X. Chen, Y. Wang, Y.G. Wen and F. Xu, 2012. Pharmacokinetics of 5-fluorouracil and cyclophosphamide in depression rats. Eur. Rev. Med. Pharmacol. Sci., 16: 427-436.
    PubMed  |  
  43. Xu, F., C.T. Gomillion, K. Neser and K.J. Burg, 2011. Tamoxifen loaded polylactide beads for breast tissue engineering following lumpectomy. Tissue Eng. Regen. Med, 8: 282-291.
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  44. Wang, Y., Y. Zeng and F. Xu, 2011. Drug safety issues of nimesulide in China-nimesulide‐induced liver injury. Pharmacoepidemiol. Drug Saf., 20: 778-779.
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  45. Ji, A., Y. Yao, O. Che, B. Wang, L. Sun, X. Li and F. Xu, 2011. Isolation and characterization of sulfated polysaccharide from the Sargassum pallidum (Turn.) C. Ag. and its sedative/hypnotic activity. J. Med. Plant Res., 5: 5240-5246.
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  46. Zhou, T., J.J. Duan, G.P. Zhou, J.Y. Cai, Z.H. Huang, Y.T. Zeng and F. Xu, 2010. Impact of depression mood disorder on the adverse drug reaction incidence rate of anticancer drugs in cancer patients. J. Int. Med. Res., 38: 2153-2159.
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  47. Zheng, Z. and F. Xu, 2010. Chinese pharmacists propose patient consent for unlabeled use of medications. J. Managed Care Pharm., 16: 640-640.
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  48. Xu, F., C.C. Yang, C. Gomillion and K.J.L. Burg, 2010. Effect of ceramide on mesenchymal stem cell differentiation toward adipocytes. Applied Biochem. Biotechnol., 160: 197-212.
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  49. He, S., Z. Zhang, F. Xu, S. Zhang and Z. Lei, 2010. Micronization of Magnolia bark extract with enhanced dissolution behavior by rapid expansion of supercritical solution. Chem. Pharm. Bull., 58: 154-159.
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  50. Xu, F., C. Gomillion, S. Maxson and K.J. Burg, 2009. In vitro interaction between mouse breast cancer cells and mouse mesenchymal stem cells during adipocyte differentiation. J. Tissue Eng. Regen. Med., 3: 338-347.
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  51. Ji, A.M., D. Su, O. Che, W.S. Li and L. Sunet al., 2009. Functional gene silencing mediated by chitosan/siRNA nanocomplexes. Nanotechnology, Vol. 20. 10.1088/0957-4484/20/40/405103..
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  52. Zhang, Z., Y. Wang, Y. Wang and F. Xu, 2008. Antiemetic placebo: Reduce adverse drug interactions between chemotherapeutic agents and antiemetic drugs in cancer patients. Med. Hypotheses, 70: 551-555.
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  53. Xu, J., J. Mercury, Z. Zhang and F. Xu, 2008. Psychological, social and behavioural factors that influence drug efficacy: A noteworthy research subject in clinical pharmacology. Br. J. Clin. Pharmacol., 66: 901-902.
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  54. Xu, F., 2008. Informing patients about drug effects using positive suggestion. J. Manag. Care Pharm., 14: 395-396.
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  55. Xu, F., 2008. Importance of emotional support from pharmacist for cancer patients. J. Oncol. Pharm. Prac., 14: 163-164.
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  56. Xu, F., 2008. Caution in prescribing antidepressants for patients with cancer. Am. J. Health Syst. Pharm., 65: 700-700.
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  57. Yang, C.C., S.E. Ellis, F. Xu and K.J. Burg, 2007. In vitro regulation of adipogenesis: Tunable engineered tissues. J. Tissue Eng. Regener. Med., Vol. 1. 10.1002/term.17.
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  58. Xu, F., 2007. Effect of personality type on pharmacodynamics through changing pharmacokinetics. Med. Hypotheses, 69: 1131-1134.
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  59. Xu, F. and K.J. Burg, 2007. Three-dimensional polymeric systems for cancer cell studies. Cytotechnology, 54: 135-143.
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  60. Xu, F., Z.G. Ou-Yang, S.H. Zhang, D.Q. Song, R.G. Shao and Y.S. Zhen, 2006. Sodium caffeate induces endothelial cell apoptosis and inhibits VEGF expression in cancer cells. Acta pharm. Sin., 41: 572-576.
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  61. Xu, F., S.H. Zhang, R.G. Shao and Y.S. Zhen, 2005. Anticancer activity of sodium caffeate and its mechanism. Acta Pharmacol. Sin., 26: 1248-1252.
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  62. Xu, F., D. Song and Y. Zhen, 2004. Inhibition of tumor metastasis by sodium caffeate and its effect on angiogenesis. Oncology, 67: 88-92.
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  63. Xu, F. and Y.S. Zhen, 2003. (-)-Epigallocatechin-3-gallate enhances anti-tumor effect of cytosine arabinoside on HL-60 cells. Acta Pharmacol. Sin., 24: 163-168.
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  64. Xu, F., Z.H. Wu, Z.Y. Zhang and H.Q. Zou, 1998. Delay of metabolism rate of ciclosporin by simvastatin in 7 Chinese healthy men. Acta Pharmacol. Sin., 19: 443-444.
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  65. Xu, F., Z.H. Wu, Z.Y. Zhan and H.Q. Zou, 1998. Concentration-dependent effect of cyclosporine on plasma lipid in renal transplant recipients. Clin. Nephrol., 50: 67-68.
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  66. Xu, F., J.B. Huang, L. Jiang, J. Xu and J. Mi, 1995. Amelioration of cyclosporin nephrotoxicity by Cordyceps sinensis in kidney-transplanted recipients. Nephrol. Dialysis Transplant., 10: 142-143.
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  67. Xu, F., Z.L. Chen, W.J. Jin, Q.D. Xie and X.H. Shi, 1993. Ideal therapeutic range of cyclosporine in whole blood in kidney-transplanted patients. Int. J. Clin. Pharmacol. Res., 13: 221-224.
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  68. Xu, F. and Y.K. Zhu, 1993. Fate of methotrexate albumin microspheres after hepatic intra-arterial injection in dogs. Acta pharmacol. Sin., 14: 553-555.
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