Dr. De-an Guo
My Social Links

Dr. De-an Guo

Professor
Chinese Academy of Sciences, China

Highest Degree
Ph.D. in Pharmacognosy from Beijing Medical University, China

Share this Profile

Area of Interest:

Biomedical Sciences
100%
TCM Quality Control
62%
Metabolism
90%
Natural Products Chemistry
75%
Pharmacokinetics
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Hou, J.J., W.Y. Wu and D.A. Guo, 2014. A single, multi-faceted, enhanced strategy to quantify the chromatographically diverse constituents in the roots of Euphorbia kansui. J. Pharmaceut. Biomed. Anal., 88: 321-330.
    CrossRef  |  
  2. Zhang, J.X., S.H. Guan, R.H. Feng, Y. Wang and Z.Y. Wu et al., 2013. Neolignanamides, lignanamides and other phenolic compounds from the root bark of Lycium chinense. J. Nat. Prod., 76: 51-58.
    CrossRef  |  
  3. Zhang, J.X., S.H. Guan, M. Yang, R.H. Feng and Y. Wang et al., 2013. Simultaneous determination of 24 constituents in Cortex Lycii using high-performance liquid Chromatography-triple quadrupole mass spectrometry. J. Pharm. Biomed. Anal., 77: 63-70.
  4. Zeng, F., W. Wang, S.H. Guan, C.R. Cheng and M. Yang et al., 2013. Simultaneous quantification of 18 bioactive constituents in Tripterygium wilfordii using liquid chromatography-electrospray ionization-mass spectrometry. Planta Med., 79: 797-805.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Yang, W.Z., T. Bo, S. Ji, X. Qiao, D.A. Guo and M. Ye, 2013. Rapid chemical profiling of saponins in the flower buds of Panax notoginseng by integrating MCI gel column chromatography and liquid chromatography/mass spectrometry analysis. Food Chem., 139: 762-769.
    CrossRef  |  
  6. Yang, W.Z., G. Ye, A.H. Meng, G. Sabir, X. Qiao, D.A. Guo and M. Ye, 2013. Rapid characterisation of flavonoids from Sophora alopecuroides L. by HPLC/DAD/ESI-MS n. Nat. Prod. Res., 27: 323-330.
    CrossRef  |  
  7. Xu, T., M. Yang, Y. Li, X. Chen and Q. Wang et al., 2013. An integrated exact mass spectrometric strategy for comprehensive and rapid characterization of phenolic compounds in licorice. Rapid Commun. Mass Spectrom., 27: 2297-2309.
    CrossRef  |  
  8. Wang, Y., S.H. Guan, Y.H. Meng, Y.B. Zhang and C.R. Cheng et al., 2013. Phenanthrenes, 9, 10-dihydrophenanthrenes, bibenzyls with their derivatives and malate or tartrate benzyl ester glucosides from tubers of Cremastra appendiculata. Phytochemistry, 94: 268-276.
    CrossRef  |  
  9. Wang, Q., S. Ji, S.W. Yu, H.X. Wang and X.H. Lin et al., 2013. Three new phenolic compounds from the roots of Glycyrrhiza yunnanensis. Fitoterapia, 85: 35-40.
    CrossRef  |  
  10. Ma, B., Z.Y. Xiao, Y.J. Chen, M. Lei and Y.H. Meng et al., 2013. Synthesis and Structure-activity relationships study of cytotoxic bufalin 3-Nitrogen-containing-ester derivatives. Steroids, 78: 508-512.
    CrossRef  |  
  11. Liu, X., W.Y. Wu, B.H. Jiang, M. Yang and D.A. Guo, 2013. Pharmacological tools for the development of traditional Chinese medicine. Trends Pharm. Sci., 34: 620-628.
    CrossRef  |  
  12. Liu, C.F., X. Qiao, K.D. Liu, W.J. Miao and Y.J. Li et al., 2013. In vivo metabolites and plasma exposure of TongMaiKeli analyzed by UHPLC/DAD/qTOF-MS and LC/MS/MS. J. Ethnopharmacol., 145: 509-516.
  13. Liang, J., W.Y. Wu, G.X. Sun, D.D. Wang and J.J. Hou et al., 2013. A dynamic multiple reaction monitoring method for the multiple components quantification of complex traditional Chinese medicine preparations: Niuhuang Shangqing pill as an example. J. Chromatogr. A, 1294: 58-69.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Li, D., S. Liu, F. Teng, W. Yang and L. Zhang et al., 2013. Temporal change of leukocytes and chemokines in aortic dissection patient: Relationship to regional lesion on aorta. Int. J. Cardiol., 168: 3065-3066.
    CrossRef  |  
  15. Jiang, B., D. Li, Y. Deng, F. Teng and J. Chen et al., 2013. Salvianolic acid a, a novel matrix metalloproteinase-9 inhibitor, prevents cardiac remodeling in spontaneously hypertensive rats. Plos One, Vol. 8. 10.1371/journal.pone.0059621.
    CrossRef  |  
  16. Gu, J., R. Feng, Z. Wu, S. Guan and J. Guo et al., 2013. A rapid and convenient method for preparative separation of three indissolvable polyphenols from Euphorbia pekinensis by the flexible application of solvent extraction combined with Counter-current chromatography. J. Sep. Sci., 36: 2366-2372.
    CrossRef  |  
  17. Feng, L.X., D.M. Zhang, C.Y. Fan, C. Ma and W.M. Yang et al., 2013. ER stress-mediated apoptosis induced by celastrol in cancer cells and important role of glycogen synthase kinase-3β in the signal network. Cell Death Dis., Vol. 4. 10.1038/cddis.2013.222.
    CrossRef  |  PubMed  |  Direct Link  |  
  18. Cheng, C.R., M. Yang, S.H. Guan, X.H. Wu and X.Y. Pang et al., 2013. Pharmacokinetics of ganoderic acid D and its main metabolite by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B, 930: 1-6.
    CrossRef  |  PubMed  |  Direct Link  |  
  19. Yue, Q.X., F.B. Xie, X.Y. Song, W.Y. Wu and B.H. Jiang et al., 2012. Proteomic studies on protective effects of salvianolic acids, notoginsengnosides and combination of salvianolic acids and notoginsengnosides against cardiac ischemic-reperfusion injury. J. Ethnopharmacol., 141: 659-667.
  20. Yuan, J., D. Yang, Y. Liang, W. Gao and Z. Ren et al., 2012. Alkaloids from areca (betel) nuts and their effects on human sperm motility in vitro. J. Food Sci., 77: T70-T78.
    CrossRef  |  PubMed  |  Direct Link  |  
  21. Ye, M., W.Z. Yang, K.D. Liu, X. Qiao and B.J. Li et al., 2012. Characterization of flavonoids in Millettia nitida var. hirsutissima by HPLC/DAD/ESI-MSn. J. Pharm. Anal., 2: 35-42.
    CrossRef  |  Direct Link  |  
  22. Yang, W.Z., M. Ye, X. Qiao, Q. Wang, T. Bo and D.A. Guo, 2012. Collision-induced dissociation of 40 flavonoid aglycones and differentiation of the common flavonoid subtypes using electrospray ionization ion-trap tandem mass spectrometry and quadrupole time-of-flight mass spectrometry. Eur. J. Mass Spectrom., 18: 493-503.
    PubMed  |  
  23. Yang, W.Z., M. Ye, X. Qiao, C.F. Liu and W.J. Miao et al., 2012. A strategy for efficient discovery of new natural compounds by integrating orthogonal column chromatography and liquid chromatography/mass spectrometry analysis: Its application in Panax ginseng, Panax quinquefolium and Panax notoginseng to characterize 437 potential new ginsenosides. Anal. Chim. Acta, 739: 56-66.
    CrossRef  |  
  24. Yang, W.Z., M. Ye, F.X. Huang, W.N. He and D.A. Guo, 2012. Biocatalysis of cycloastragenol by filamentous fungi to produce unexpected triterpenes. Adv. Synth. Catal., 354: 527-539.
    CrossRef  |  Direct Link  |  
  25. Yang, M., Z.Q. Lu, K. Yu, Q.R. Wang and X. Chen et al., 2012. Studies on the fragmentation pathways of ingenol esters isolated from Euphorbia esula using IT-MSn and Q-TOF-MS/MS methods in electrospray ionization mode. Int. J. Mass Spectrom., 323: 55-62.
    CrossRef  |  
  26. Yang, M., C. Cheng, J. Yang and D.A. Guo, 2012. Metabolite profiling and characterization for medicinal herbal remedies. Curr. Drug Metab., 13: 535-557.
    Direct Link  |  
  27. Xu, P., S. Guan, R. Feng, R. Tang and D. Guo, 2012. Separation of Four homoisoflavonoids from caesalpinia sappan by high-speed counter-current chromatography. Phytochem. Anal., 23: 228-231.
    CrossRef  |  Direct Link  |  
  28. Wu, X., J. Ruan, V.C. Yang, Z. Wu and J. Lou et al., 2012. Three new acetylated benzyl-β-resorcylate glycosides from Cassia obtusifolia. Fitoterapia, 83: 166-169.
    CrossRef  |  PubMed  |  Direct Link  |  
  29. Wu, H., R.H. Feng, S.G. Guan, W.B. Yu and W. Man et al., 2012. Rapid preparative isolation of a new phenylpropanoid glycoside and four minor compounds from Sparganium stoloniferum using high-speed counter-current chromatography as a fractionation tool. J. Sep. Sci., 35: 1160-1166.
    CrossRef  |  PubMed  |  Direct Link  |  
  30. Wang, W.B., L.X. Feng, Q.X. Yue, W.Y. Wu and S.H. Guan et al., 2012. Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90. J. Cell Physiol., 227: 2196-2206.
    CrossRef  |  Direct Link  |  
  31. Uzuner, H., R. Bauer, T.P. Fan, D.A. Guo and A. Dias et al., 2012. Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities. J. Ethnopharmacol., 140: 458-468.
    CrossRef  |  PubMed  |  Direct Link  |  
  32. Tao, S.J., Y. Wang, X. Zhang, S.H. Guan and D.A. Guo, 2012. Biotransformation of gambogenic acid by Chaetomium globosum CICC 2445. Nat. Prod. Commun., 7: 197-198.
    PubMed  |  
  33. Tang, R.N., X.B. Qu, S.H. Guan, P.P. Xu, Y.Y. Shi and D.A. Guo, 2012. Chemical constituents of Spatholobuss uberectus. Chinese J. Nat. Med., 10: 32-35.
    CrossRef  |  PubMed  |  Direct Link  |  
  34. Song, W., M. Lei, K. Zhao, L. Hu and Y. Meng et al., 2012. Ceric ammonium nitrate-promoted oxidative coupling reaction for the synthesis and evaluation of a series of anti-tumor amide anhydrovinblastine analogs. Bioorg. Med. Chem. Lett., 22: 387-390.
    CrossRef  |  PubMed  |  Direct Link  |  
  35. Song, W., L. Hu, Y. Meng, L. Ma, D. Guo, X. Liu and L. Hu, 2012. The effect of vindoline C-16 substituents on the biomimetic coupling reaction: Synthesis and cytotoxicity evaluation of the corresponding vinorelbine analogues. Bioorg. Med. Chem. Lett., 22: 3485-3487.
    CrossRef  |  PubMed  |  Direct Link  |  
  36. Shi, Y.Y., S.H. Guan, R.N. Tang, S.J. Tao and D.A. Guo, 2012. Simultaneous determination of atractylenolide II and atractylenolide III by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of Atractylodes Macrocephala Rhizoma extract. Biomed. Chromatogr., 26: 1386-1392.
    CrossRef  |  
  37. Shi, Y.Y., S.H. Guan, R.N. Tang, S.J. Tao and D.A. Guo et al., 2012. Simultaneous determination of four sesquiterpenoids in Atractylodes Macrocephala Rhizoma by GC-FID: Optimisation of an ultrasound-assisted extraction by central composite design. Phytochem. Anal., 23: 408-414.
    CrossRef  |  
  38. Qiao, X., M. Ye, C.F. Liu, W.Z. Yang, W.J. Miao, J. Dong and D.A. Guo, 2012. A tandem mass spectrometric study of bile acids: Interpretation of fragmentation pathways and differentiation of steroid isomers. Steroids, 77: 204-211.
    CrossRef  |  PubMed  |  Direct Link  |  
  39. Qiao, X., M. Ye, C. Xiang, T. Bo and W.Z. Yang et al., 2012. Metabolic regulatory effects of licorice: A bile acid metabonomic study by liquid chromatography coupled with tandem mass spectrometry. Steroids, 77: 745-755.
    Direct Link  |  
  40. Qiao, X., M. Ye, C. Xiang, Q. Wang, C.F. Liu, W. J. Miao and D.A. Guo, 2012. Analytical strategy to reveal the in vivo process of multi-component herbal medicine: A pharmacokinetic study of licorice using liquid chromatography coupled with triple quadrupole mass spectrometry. J. Chromatogr. A, 1258: 84-93.
    CrossRef  |  
  41. Qiao, X., G. Ye, C.F. Liu, Z.X. Zhang and Q. Tu et al., 2012. Chemical analysis of Eriocaulon buergerianum and adulterating species by high-performance liquid chromatography with diode array detection and electrospray ionization tandem mass spectrometry. J. Pharm. Biomed. Anal., 57: 133-142.
    CrossRef  |  PubMed  |  Direct Link  |  
  42. Pan, S.N., Y.H. Wang, L.X. Feng, C.Y. Fan, D.A. Guo, X. Liu and J.L. Fan, 2012. [Study on proteomics of Hela cell apoptosis in bufalin-induced human cervical carcinoma]. Zhongguo Zhong Yao Za Zhi., 13: 1998-2004.
    PubMed  |  
  43. Miao, W.J., Q. Wang, T. Bo, M. Ye and X. Qiao et al., 2012. Rapid characterization of chemical constituents and rats metabolites of the traditional Chinese patent medicine Gegen-Qinlian-Wan by UHPLC/DAD/qTOF-MS. J. Pharm. Biomed. Anal., 72: 99-108.
    CrossRef  |  
  44. Li, H.F., X.Y. Guan, W.Z. Yang, K.D. Liu and M. Ye et al., 2012. Antioxidant flavonoids from Epimedium wushanense. Fitoterapia, 83: 44-48.
    CrossRef  |  Direct Link  |  
  45. Jiang, B., K. Sun, M. Li, Y. Wang and L. Zhuang et al., 2012. Study of luan-pao-prescription on ovarian dysfunction in rats. J. Ethnopharmacol., 141: 653-658.
    CrossRef  |  Direct Link  |  
  46. Huang, F.X., X.H. Lin, W.N. He, W. Song, M. Ye, W.Z. Yang and D.A. Guo, 2012. Two new oxidation products obtained from the biotransformation of asiatic acid by the fungus Fusarium avenaceum AS 3.4594. J. Asian Nat. Prod. Res., 14: 1039-1045.
    CrossRef  |  PubMed  |  Direct Link  |  
  47. Huang, F.X., W.Z. Yang, F. Ye, J.Y. Tian and H.B. Hu et al., 2012. Microbial transformation of ursolic acid by Syncephalastrum racemosum (Cohn) Schroter AS 3.264. Phytochemistry, 82: 56-60.
    CrossRef  |  PubMed  |  Direct Link  |  
  48. Fan, C.Y., L.X. Feng, J.L. Fan, D.A. Guo and X. Liu, 2012. Recent progress in protein recombinant expression. Biotechnology, 2: 76-80.
  49. Fan, C.Y., L.X. Feng, D.M. Zhang, S.N. Pan, X. Liu, D.A. Guo and J.L. Fan, 2012. The expression and purification of the human proteome subunit- PSMB1 and its application in in vitro screening of proteome inhibitors. Chin. J. Biotech., 2: 233-242.
  50. Du, X.G., W. Wang, Q.Y. Zhang, J. Cheng, B. Avula, I.A. Khan and D.A. Guo, 2012. Identification of xanthones from Swertia punicea using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 26: 2913-2923.
    CrossRef  |  Direct Link  |  
  51. Da, J., W.Y. Wu, J.J. Hou, H.L. Long and S. Yao et al., 2012. Comparison of two officinal Chinese pharmacopoeia species of Ganoderma based on chemical research with multiple technologies and chemometrics analysis. J. Chromatogr. A, 1222: 59-70.
    CrossRef  |  PubMed  |  Direct Link  |  
  52. Cheng, C.R., Y.F. Li, P.P. Xu, R.H. Feng, M. Yang, S.H. Guan and D.A. Guo, 2012. Preparative isolation of triterpenoids from Ganoderma lucidum by counter-current chromatography combined with pH-zone-refining counter-current. Food Chem., 130: 1010-1016.
    CrossRef  |  Direct Link  |  
  53. Cheng, C.R., M. Yang, K. Yu, S.H. Guan, A. Millar, X.Y. Pang and D.A. Guo, 2012. Identification of metabolites of ganoderic acid D by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Drug Metab. Dispos., 40: 2307-2314.
    CrossRef  |  PubMed  |  Direct Link  |  
  54. Chen, W.F., Q.G. Gao, Z.J. Dai, A.W.C. Kung, D.A. Guo and M.S. Wong, 2012. Estrogenic effects of ginsenoside Rg1 in endometrial cells in vitro were not observed in immature CD-1 mice or ovariectomized mice model. Menopause, 19: 1052-1061.
    PubMed  |  
  55. Chen, H., J. Yin, Y.P. Deng, M. Yang and L.L. Xu et al., 2012. The protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats. BMC Complem. Altern. Med., Vol. 12. 10.1186/1472-6882-12-53.
    CrossRef  |  Direct Link  |  
  56. Chakrabortee, S., Y. Liu, L. Zhang, H.R. Matthews and H.R. Zhang et al., 2012. Macromolecular and small-molecule modulation of intracellular Aβ42 aggregation and associated toxicity. Biochem. J., 442: 507-515.
    CrossRef  |  PubMed  |  Direct Link  |  
  57. Zhang, X., M. Ye, Y.J. Gong, L.M. Feng, S.J. Tao, J. Yin and D.A. Guo, 2011. Biotransformation of pseudolaric acid B by Chaetomium globosum. Process. Biochem., 46: 2064-2067.
    Direct Link  |  
  58. Zhang, X., M. Ye, Y.H. Dong, H.B. Hu, J. Yin and D.A. Guo, 2011. Biotransformation of bufadienolides by cell suspension cultures of Saussurea involucrate. Phytochemistry, 72: 1779-1785.
    Direct Link  |  
  59. Xiang, C., X. Qiao, Q. Wang, R. Li, W. Miao, D. Guo and M. Ye, 2011. From single compounds to herbal extract: A strategy to systematically characterize the metabolites of licorice in rats. Drug Metab. Dispos., 39: 1597-1608.
    CrossRef  |  
  60. Wu, X.H., J.J. Cai, J.L. Ruan J.S. Lou and H.Q. Duan et al., 2011. Acetylated anthraquinone glycosides from Cassia obtusifolia. J. Asian Nat. Prod. Res., 13: 486-491.
    CrossRef  |  
  61. Wang, Y., F. Xu, J. Chen, X. Shen and Y. Deng et al., 2011. Matrix metalloproteinase-9 induces cardiac fibroblast migration, collagen and cytokine secretion: Inhibition by salvianolic acid B from Salvia miltiorrhiza. Phytomedicine, 19: 13-19.
    CrossRef  |  Direct Link  |  
  62. Qiao, X., W.Z. Yang, D.A. Guo and M. Ye, 2011. Extraction, separation, detection and structural analysis of flavonoids. Curr. Org. Chem., 15: 2541-2566.
    CrossRef  |  
  63. Qiao, X., W.N. He, C. Xiang, J. Han, L.J. Wu, D.A. Guo and M. Ye, 2011. Qualitative and quantitative analyses of flavonoids in Spirodela polyrrhiza by high-performance liquid chromatography coupled with mass spectrometry. Phytochem. Anal., 22: 475-483.
    PubMed  |  
  64. Qiao, X., M. Ye, Y.H. Liang, W.Z. Yang and D.A. Guo, 2011. Retention behaviors of natural products in reversed-phase liquid chromatography using mobile phase comprising methanol, acetonitrile and water. J. Sep. Sci., 34: 169-175.
    PubMed  |  Direct Link  |  
  65. Qiao, X., M. Ye, D.L. Pan, W.J. Miao, C. Xiang, J. Han and D.A. Guo, 2011. Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: Simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry. J. Chromatogr. A, 1218: 107-117.
    PubMed  |  
  66. Qiao, X., J. Han, M. Xu, Z.C. Zhang, M. Ye, G. Ye and D.A. Guo, 2011. Metabolic profiling of Guan Xin II prescription based on metabolic fingerprinting and chemical analysis. J. Pharm. Biomed. Anal., 54: 789-798.
    Direct Link  |  
  67. Pang, X., J. Cheng, K.W. Krausz, D.A. Guo, F.J. Gonzalez, 2011. Pregnane X receptor-mediated induction of Cyp3a by black cohosh. Xenobiotica, 41: 112-123.
    CrossRef  |  
  68. Liu, X., Y. Wang, C. Ma, L. Zhang and W. Wu et al., 2011. Proteomic assessment of tanshinone IIA sodium sulfonate on doxorubicin induced nephropathy. Am. J. Chin. Med., 39: 395-409.
    Direct Link  |  
  69. Liu, X. and D.A. Guo, 2011. Application of proteomics in the mechanistic study of traditional Chinese medicine. Biochem. Soc. Trans., 39: 1348-1352.
    PubMed  |  
  70. Liu, P., J.H. Sun, M. Xu, H. Guo and H.Z. Guo et al., 2011. Characterization of diterpenoids in the bark of Pseudolarix kaempferi by HPLC-ESI/MSn. Yao Xue Xue Bao, 46: 213-220.
    Direct Link  |  
  71. Liu, K.D., X. Qiao, D.A. Guo and M. Ye, 2011. HPLC fingerprint analysis of Drynaria Rhizome. Chinese Herbal Med., 42: 510-514.
  72. Liang, Y.H., M. Ye, X. Qiao, H.J. Yang, X.L. Wang and D.A. Guo, 2011. Flavan-3-ols from the Rhizomes of Drynaria fortunei. Phytochemistry, 72: 1876-1882.
    Direct Link  |  
  73. Liang, Y.H., M. Ye, J. Han, B.R. Wang and D.A. Guo, 2011. Lignans and flavonoids from Drynaria Rhizome. Chinese Herbal Med., 42: 25-30.
  74. Li, R., M. Ye and D.A. Guo, 2011. Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. B, 879: 2751-2758.
    PubMed  |  
  75. Li, R., C. Xiang, M. Ye, H.F. Li, X. Zhang and D.A. Guo, 2011. Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species. Food Chem., 126: 1890-1895.
    CrossRef  |  Direct Link  |  
  76. Li, H.F., X.Y. Guan, M. Ye, C. Xiang, C.H. Lin, C. Sun and D.A. Guo, 2011. Qualitative and quantitative analyses of Epimedium wushanense by high-performance liquid chromatography coupled with diode array detection and electrospray ionization tandem mass spectrometry. J. Sep. Sci., 34: 1437-1446.
    CrossRef  |  
  77. Hou, J.J., W.Y. Wu, J. Da, S. Yao and H.L. Long et al., 2011. Ruggedness and robustness of conversion factors in method of simultaneous determination of multi-components with single reference standard. J. Chromatogr. A, 1218: 5618-5627.
    PubMed  |  
  78. He, X., W. Yang, M. Ye, Q. Wang and D. Guo, 2011. Differentiation of cuscuta chinensis and cuscuta australis by HPLC-DAD-MS analysis and HPLC-UV quantitation. Planta Med., 77: 1950-1957.
    CrossRef  |  
  79. Guan, X.Y., H.F. Li, W.Z. Yang, C.H. Lin and C. Sun et al., 2011. HPLC-DAD-MS(n) analysis and HPLC quantitation of chemical constituents in Xian-ling-gu-bao capsules. J. Pharm. Biomed. Anal., 55: 923-933.
    CrossRef  |  
  80. Grienke, U., J. Mihaly-Bison, D. Schuster, D.A. Guo and S.H. Guan et al., 2011. Computer-aided discovery of farnesoid X receptor-inducing triterpenes from Ganoderma lucidum. Bio. Med. Chem., 19: 6779-6791.
  81. Feng, L.X., C.J. Jing, K.L. Tang, L. Tao and Z.W. Cao et al., 2011. Clarifying the signal network of salvianolic acid B using proteomic assay and bioinformatic analysis. Proteomics, 11: 1473-1485.
    PubMed  |  
  82. Fan, L., R. Pu, X. Liu, J. Han, B.R. Wang and D.A. Guo, 2011. Anti-PAF aggregation activity of Carthamus tinctorius. Chin. J. Chinese Mater. Med., 36: 67-69.
  83. Cheng, C.R., M. Yang, Z.Y. Wu, Y. Wang and F. Zeng et al., 2011. Fragmentation pathways of oxygenated tetracyclic triterpenoids and their application in the qualitative analysis of Ganoderma lucidum by multistage tandem mass spectrometry. Rapid Commun. Mass Spectrom., 25: 1323-1335.
    CrossRef  |  
  84. Zhao, H., Y. Luo, C. Lu, N. Lin and C. Xiao et al., 2010. Enteric mucosal immune response might trigger the immunomodulation activity of Ganoderma lucidum polysaccharide in mice. Planta Med., 76: 223-227.
    PubMed  |  
  85. Zhao, H., M. Fan, L. Fan, J. Sun and D.A Guo, 2010. Liquid chromatography-tandem mass spectrometry analysis of metabolites in rats after administration of prenylflavonoids from Epimediums. J. Chromatogr. B, 8787: 1113-1124.
    CrossRef  |  PubMed  |  
  86. Zeng, F., W. Wang, Y. Wu, M. Dey and M. Ye et al., 2010. Two prenylated and C-methylated flavonoids from Tripterygium wilfordii. Planta Med., 76: 1596-1599.
    Direct Link  |  
  87. Yue, Q.X., X. Liu and D.A. Guo, 2010. Microtubule-binding natural products for cancer therapy. Plant. Med., 76: 1037-1043.
    CrossRef  |  
  88. Yin, Y., M. Yang, Y. Wang, X. Liu and W. Wu et al., 2010. Tanshinone IIA increases mRNA expression of efflux transporters in cultured human intestinal cell. Am. J. Chin Med., 38: 995-1004.
    CrossRef  |  Direct Link  |  
  89. Wu, X.H., J.L. Ruan, C.R. Chen, Z.Y. Wu and S.H. Guan et al., 2010. Benzyl-beta-resorcylates from Cassia obtusifolia. Fitoterapia, 81: 617-620.
    PubMed  |  
  90. Uzuner, H., T.P. Fan, A. Dias, D.A. Guo, H.S. El-Nezami and Q. Xu, 2010. Establishing an EU-China consortium on traditional Chinese medicine research. Chin. Med., 5: 42-42.
    CrossRef  |  
  91. Qiao, X., X. Zhang, M. Ye, Y.F. Su and J. Dong et al., 2010. Rapid characterization of triterpene saponins from Conyza blinii by liquid chromatography coupled with mass spectrometry. Rapid Commun. Mass Spectrom, 24: 3340-3350.
    CrossRef  |  
  92. Qiao, X., J. Han, W.N. He, T. Wu, B.R. Wang, M. Ye and D.A. Guo, 2010. Chemical fingerprint of commercial Radix Echinopsis and quantitative analysis of alpha-terthienyl. J. Sep. Sci., 33: 530-538.
    CrossRef  |  
  93. Liang, Y.H., W. Wang, S.W. Yu, M. Ye and X.H. He et al., 2010. A new chiratane type triterpenoid from the rhizomes of Drynaria fortunei. Fitoterapia, 81: 988-991.
    CrossRef  |  
  94. Liang, Y.H., M. Ye, L.Z. Zhang, H.F. Li, J. Han, B.R. Wang and D.A. Guo, 2010. Two new phenolic acids from Drynaria Rhizome. Acta Pharmaceut. Sin., 45: 874-878.
  95. Li, B.J., C. Xiang, X.W. Yang, L.J. Wu, D.A. Guo and M. Ye, 2010. Fingerprint analysis ofTongmai granule by HPLC-MS technique. Acta Pharm. Sin., 45: 1410-1414.
  96. Jing, C.J., X.H. Chen, X. Liu, K.S. Bi and D.A. Guo, 2010. Determination of the binding rate of rat plasma protein with salvianolic acid B. Acta Pharmaceut. Sin., 45: 343-346.
    PubMed  |  
  97. Huang, H., G. Chen, Z. Lu, J. Zhang and D.A. Guo, 2010. Identification of seven metabolites of oxyresveratrol in rat urine and bile using liquid chromatography/tandem mass spectrometry. Biomed. Chromatogr., 24: 426-432.
    PubMed  |  
  98. He, X.H., W.Z. Yang, A.H. Meng, W.N. He, D.A. Guo and M. Ye, 2010. Two new lignan glycosides from the seeds of Cuscuta chinensis. J. Asian Nat. Prod. Res., 12: 934-939.
    PubMed  |  
  99. He, W.N., J.G. Dai, M. Ye, L.J. Wu and D.A. Guo, 2010. Microbial transformation of asiatic acid by Alternaria longipes. J. Asian Nat. Prod. Res., 12: 760-764.
    PubMed  |  Direct Link  |  
  100. Guo, D.A., 2010. Quality Control of Chinese Salvia. China Science Press, Beijing, China.
  101. Du, X.G., W. Wang, S.P. Zhang, X.P. Pu and Q.Y. Zhang et al., 2010. Neuroprotective xanthone glycosides from Swertia punicea. J. Nat. Prod., 73: 1422-1426.
    CrossRef  |  
  102. Cui, Y.J., S.H. Guan, L.X. Feng, X.Y. Song and C. Ma et al., 2010. Cytotoxicity of 9,11-Dehydroergosterol Peroxide Isolated from Ganoderma lucidum and its target-related proteins. Nat. Prod. Commun., 5: 1183-1186.
    PubMed  |  
  103. Cheng, C.R., Q.X. Yue, Z.Y. Wu, X.Y. Song and S.J. Tao et al., 2010. Cytotoxic triterpenoids from Ganoderma lucidum. Phytochemistry, 71: 1579-1585.
    CrossRef  |  
  104. Zhang, H.N., C.N. An, M. Xu, D.A. Guo, M. Li and X.P. Pu, 2009. Protocatechuic acid inhibits rat pheochromocytoma cell damage induced by a dopaminergic neurotoxin. Biol. Pharm. Bull., 32: 1866-1869.
    PubMed  |  
  105. Yang, M., J. Sun, Z. Lu, G. Chen and S. Guan et al., 2009. Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. J. Chromatogr. A, 1216: 2045-2062.
    CrossRef  |  Direct Link  |  
  106. Xin, X.L., L.B. Zhan, F.Y. Li, X.C. Ma, K.X. Liu, J. Han and D.A. Guo, 2009. Microbial transformation of bufotalin by Alternaria alternata AS 3.4578. J. Asian Nat. Prod Res., 11: 7-11.
    CrossRef  |  
  107. Wang, W., Z. Ali, X.C. Li, T.A. Smillie, D.A. Guo and I.A. Khan, 2009. New clerodane diterpenoids from Casearia sylvestris. Fitoterapia, 80: 404-407.
    CrossRef  |  
  108. Tao, S.J., S.H. Guan, Z.Q. Lu, G.T. Chen and N. Sha et al., 2009. Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi. J. Nat. Prod., 72: 117-124.
    CrossRef  |  
  109. Sun, J.H., M. Yang, X.C. Ma, J. Kang, J. Han and D.A. Guo, 2009. Microbial biotransformation of cryptotanshinone by Cunninghamella elegans and its application for metabolite identification in rat bile. J. Asian Nat. Prod. Res., 11: 482-489.
    CrossRef  |  
  110. Sha, N., S.H. Guan, Z.Q. Lu, G.T. Chen and H.L. Huang et al., 2009. Cytotoxic constituents of Chinese propolis. J. Nat. Prod., 72: 799-801.
    CrossRef  |  
  111. Sha, N., J.Q. Zhang, H.L. Huang, Z.Q. Lu and G.T. Chen et al., 2009. Simultaneous quantification of eight major bioactive phenolic compounds in Chinese propolis by high-performance liquid chromatography. Nat. Prod. Commun., 4: 813-818.
    PubMed  |  
  112. Qiao, X., Y.T. Zhang, M. Ye, B.R. Wang, J. Han and D.A. Guo, 2009. Analysis of chemical constituents and taxonomic similarity of Salvia species in China using LC/MS. Plant. Med., 75: 1613-1617.
    CrossRef  |  
  113. Ma, C., Q.X. Yue, S.H. Guan, W.Y. Wu and M. Yang et al., 2009. Proteomic analysis of possible target-related proteins of cyclophosphamide in mice thymus. Food Chem. Toxicol., 47: 1841-1847.
    CrossRef  |  
  114. Li, F., H.Y. Zhao, M. Xu, L. Zhou, J. Han, B.R. Wang and D.A. Guo, 2009. Simultaneous determination of ten components in water extract of Carthamus tinctorius L. using RP-HPLC-DAD. J. Chromatogr A, 1216: 2063-2070.
  115. Lau, W.S., W.F. Chen, R.Y. Chan, D.A. Guo and M.S. Wong, 2009. Mitogen-activated protein kinase (MAPK) pathway mediates the oestrogen-like activities of ginsenoside Rg1 in human breast cancer (MCF-7) cells. Br. J. Pharmacol., 156: 1136-1146.
    CrossRef  |  
  116. Jiang, B., W. Wu, M. Li, L. Xu and K. Sun et al., 2009. Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats. Plant. Med., 75: 1286-1292.
    CrossRef  |  
  117. Jiang, B., L. Zhang, Y. Wang, M. Li and W. Wu et al., 2009. Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo. Food Chem. Toxicol., 47: 1538-1544.
    CrossRef  |  
  118. Huang, H.L., J.Q. Zhang, G.T. Chen, Z.Q. Lu and N. Sha et al., 2009. Simultanenous determination of oxyresveratrol and resveratrol in rat bile, urine and tissues by HPLC after oral administration of Smilax china extract. Nat. Prod. Commun., 4: 825-830.
    Direct Link  |  
  119. Zhou, L., J. Kang, L. Fan, X.C. Ma and H.Y. Zhao et al., 2008. High performance liquid chromatography-DAD method for the simultaneous determination of 7 components in Cortex fraxini. J. Pharm. Biomed. Anal., 47: 39-46.
  120. Zhao, H.Y., J.H. Sun, M.X. Fan, L. Fan and L. Zhou et al., 2008. Analysis of phenolic compounds in Epimedium plants using liquid chromatography coupled with electrospray ionization mass spectrometry. J. Chromatogr. A, 1190: 157-181.
    CrossRef  |  
  121. Zhang, Z.C., M. Xu, S.F. Sun, X. Qiao, B.R. Wang, J. Han and D.A. Guo, 2008. Metabolic analysis of four phenolic acids in rat by liquid chromatography-tandem mass spectrometry. J. Chromatogr. B, 871: 7-14.
    CrossRef  |  
  122. Zhang, Z.C., M. Xu, S.F. Sun, H. Guo and X. Qiao et al., 2008. Determination of danshensu in rat plasma and tissues by high-performance liquid chromatography. J. Chromatogr. Sci., 46: 184-190.
    CrossRef  |  Direct Link  |  
  123. Zhang, J.Q., M. Yang, B.H. Jiang, H.L. Huang and G.T. Chen et al., 2008. Analysis of major chemical constituents in Luan-Pao-Prescription using liquid chromatography coupled with electrospray ionization mass spectrometry. Nat. Prod. Commun., 3: 697-704.
  124. Zhang, J.Q., H.L. Huang, G.T. Chen, Z.Q. Lu and S.J. Tao et al., 2008. LC-DAD analysis of six bioactive constituents in rat urine and bile after oral administration of Luan-Pao-Prescription. Chromatographia, 67: 325-329.
    CrossRef  |  
  125. Yue, Q.X., Z.W. Cao, S.H. Guan, X.H. Liu and L. Tao et al., 2008. Proteomic characterization of the cytotoxic mechanism of ganoderic acid D and computer automated estimation of the possible drug-target network. Mol. Cell Proteomics, 7: 949-961.
    PubMed  |  
  126. Yue, Q.X., F.B. Xie, S.H. Guan, C. Ma and M. Yang et al., 2008. Interaction of Ganoderma triterpenes with doxorubicin and proteomic characterization of the possible molecular targets of Ganoderma triterpenes. Cancer Sci., 99: 1461-1470.
    CrossRef  |  
  127. Ye, M. and D.A. Guo, 2008. A new bufadienolide obtained from the biotransformation of cinobufagin by Alternaria alternata. Nat. Prod. Res., 22: 26-30.
    PubMed  |  
  128. Yao, Y., W.Y. Wu, S.H. Guan, B.H. Jiang and M. Yang et al., 2008. Proteomic analysis of differential protein expression in rat platelets treated with notoginsengnosides. Phytomedicine, 15: 800-807.
    CrossRef  |  
  129. Yao, Y., W.Y. Wu, A.H. Liu, S.S. Deng, K.S. Bi, X. Liu and D.A. Guo, 2008. Interaction of salvianolic acids and notoginsengnosides in inhibition of ADP-induced platelet aggregation. Am. J. Chin. Med., 36: 313-328.
    CrossRef  |  
  130. Yao, Y., A.H. Liu, W.Y. Wu, S.H. Guan and B.H. Jiang et al., 2008. Possible target-related proteins of salvianolic acids in rat platelets. Phytochem. Lett., 1: 135-138.
    CrossRef  |  
  131. Xu, M., J. Han, H.F. Li, L. Fan, A.H. Liu and D.A. Guo, 2008. Stability analysis of total phenolic acids and salvianolic acid B from Salvia miltiorrhiza. Nat. Prod. Commun., 3: 669-676.
  132. Xin, X.L., X.C. Ma, K.X. Liu, J. Han, B.R. Wang and D.A. Guo, 2008. Microbial transformation of alantolactone by Mucor polymorphosporus. J. Asian Nat. Prod. Res., 10: 933-937.
    CrossRef  |  
  133. Wu, Y.P., X.M. Zhao, S.D. Pan, D.A. Guo and R. Wei et al., 2008. Salvianolic Acid B inhibits platelet adhesion under conditions of flow by a mechanism involving the collagen receptor α2β1. Thromb. Res., 123: 298-305.
    CrossRef  |  
  134. Tao, S., G. Chen, M. Yang, S. Deng, J. Zhang and D.A. Guo, 2008. Identification of the major constituents in Shi-Quan-Da-Bu decoction by HPLC-DAD-ESI-MS. Nat. Prod. Commun., 3: 689-696.
  135. Su, Y., M. Lu, F. Yang, C. Li and L. Di et al., 2008. Six new glucose esters of 3-nitropropanoic acid from Indigofera kirilowii. Fitoreapia, 79: 451-455.
    CrossRef  |  
  136. Su, Y., L. Chen, D. Wang, X. Chai and D. Guo, 2008. A new labdane diterpenoid arabinoside from Conyza blinii. Nat. Prod. Res., 22: 521-524.
    CrossRef  |  
  137. Qiao, X., J. Han, M. Xu, Z.C. Zhang and S.F. Sun et al., 2008. Characterization of chemical constituents in Guan Xin II decoction by liquid chromatography coupled with electrospray ionization-mass spectrometry. Planta Medica, 74: 1720-1729.
    CrossRef  |  
  138. Niu, J., X.C. Ma, X.L. Xin, H.W. Jin and D.A. Guo, 2008. Structural determination of two new sesquiterpenes biotransformed from germacrone by Mucor alternata. Magnet. Resonance Chem., 46: 178-181.
    CrossRef  |  
  139. Ma, X.C., X.L. Xin, K.X. Liu, J. Han and D.A. Guo, 2008. Microbial transformation of cinobufagin by Syncephalastrum racemosum. J. Nat. Prod., 71: 1268-1270.
    CrossRef  |  Direct Link  |  
  140. Ma, X.C., X.L. Xin, B.J. Zhang, F.Y. Li, K.X. Liu and D.A. Guo, 2008. Structural determination of flavonoids from Sorphora flavescens. Magnet. Resonance Chem., 46: 903-906.
    CrossRef  |  Direct Link  |  
  141. Ma, X.C. and D.A. Guo, 2008. Simultaneous determination of nine major flavonoids in Sophora flavescens by high performance liquid chromatography. Chromatographia, 68: 471-474.
  142. Ma, C., S.H. Guan, M. Yang, X. Liu and D.A. Guo, 2008. Differential protein expression in mouse splenic mononuclear cells treated with polysaccharides from spores of Ganoderma lucidum. Phytomedicine, 15: 268-276.
    CrossRef  |  
  143. Lu, Z.Q., S.H. Guan, X.N. Li, G.T. Chen and J.Q. Zhang et al., 2008. Cytotoxic diterpenoids from Euphorbia helioscopia. J. Nat. Prod., 71: 873-876.
    PubMed  |  
  144. Lu, Z.Q., J.Q. Zhang, G.T. Chen, H.L. Huang and S.H. Guan et al., 2008. Ingenane diterpenes from Euphorbia esula. Phytochemistry, 69: 812-819.
    PubMed  |  
  145. Liu, F., D. Ren, D.A. Guo, Y. Pan, H. Zhang and P. Hu, 2008. Method development for gypenosides fingerprint by high performance liquid chromatography with diode-array detection and the addition of internal standard. Chem. Pharm. Bull., 56: 389-393.
    PubMed  |  
  146. Liang, Y., A.H. Liu, R.X. Liu, S. Qin and J.H. Sun et al., 2008. Simultaneous determination and pharmacokinetics of five bufadienolides in rat plasma after oral administration of Chansu extract by SPE-HPLC method. J. Pharm. Biomed. Anal., 46: 442-448.
    Direct Link  |  
  147. Li, X.N., Z.Q. Lu, S. Qin, H.X. Yan and M. Yang et al., 2008. Tonkinensines A and B, two novel alkaloids from Sophora tonkinensis. Tetrahedron Lett., 49: 3797-3801.
    CrossRef  |  
  148. Li, X., Z. Lu, G. Chen, H. Yan and N. Sha et al., 2008. NMR spectral asiignments of isoprenylated flavanones from Sophora tonkiensis. Magnet. Resonance Chem., 46: 898-902.
  149. Li, X., N. Sha, H.X. Yan, X.Y. Pang and S. Guan et al., 2008. Iaoprenylate-substituted flavonoids from the roots of Sophora tonkinensis. Phytochem. Lett., 1: 163-167.
  150. Lau, W.S., R.Y. Chan, D.A. Guo and M.S. Wong, 2008. Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway. J. Steroid Biochem. Mol. Biol., 108: 64-71.
    CrossRef  |  PubMed  |  
  151. Kang, J., L. Zhou, J.H. Sun, M. Ye, J. Han, B.R. Wang and D.A. Guo, 2008. Three new compounds from the roots of Saposhnikovia divaricata. J. Asian Nat. Prod. Res., 10: 971-976.
    CrossRef  |  
  152. Kang, J., L. Zhou, J.H. Sun, J. Han and D.A. Guo, 2008. Analysis of linear-type furanocoumarins in Angelica dahurica by liquid chromatograph with electrospray ionization tandem mass spectrometry. J. Pharm. Biomed. Anal., 47: 778-785.
  153. Kang, J., J.H. Sun, L. Zhou, M. Ye, J. Han, B.R. Wang and D.A. Guo, 2008. Characterization of compounds from the roots of Saposhnikovia divaricata by high‐performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 22: 1899-1911.
    CrossRef  |  Direct Link  |  
  154. Jiang, B., L. Zhang, M. Li, W. Wu, M. Yang, J. Wang and D.A. Guo, 2008. Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress. Food Chem. Toxicol., 46: 1510-1515.
    CrossRef  |  
  155. Huang, H., J. Zhang, G. Chen, Z. Lu and X. Wang et al., 2008. High performance liquid chromatographic method for the determination and pharmacokinetic studies of oxyresveratrol and resveratrol in rat plasma after oral administration of Smilax china extract. Biomed. Chromatogr., 22: 421-427.
    CrossRef  |  
  156. Han, J., M. Ye, X. Qiao, M. Xu, B.R. Wang and D.A. Guo, 2008. Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry. J. Pharmaceut. Biomed. Anal., 47: 516-525.
    CrossRef  |  
  157. Han, J., M. Ye, M. Xu, X. Qiao and H. Chen et al., 2008. Comparison of phenolic compounds of rhubarbs in the section deserticola with Rheum palmatum by HPLC-DAD-ESI-MSn. Planta Medica, 74: 873-879.
    CrossRef  |  
  158. Guan, S.H., Z.M. Zhang, J.M. Xia, X. Liu, C. Ma and D.A. Guo, 2008. Three new lignan glycosides from the stems of Akebia trifolia. Magnet. Resonance Chem., 46: 186-190.
  159. Guan, S.H., J.M. Xia, M. Yang, X.M. Wang, X. Liu and D.A. Guo, 2008. Cytotoxic lanostanoid triterpenes from Ganoderma lucidum. J. Asian Nat. Prod. Res., 10: 695-700.
    CrossRef  |  
  160. Cui, Y.J., X.F. Liu, J. Han, B.R. Wang and D.A. Guo, 2008. Biotransformation of podophyllotoxin by cell suspenmsion culture and root cultures. China J. Chin. Mater. Med., 33: 989-991.
    PubMed  |  
  161. Chen, G., M. Yang, Y. Song, Z. Lu and J. Zhang et al., 2008. Microbial transformation of ginsengnoside Rb1 by Acremonium strictum. Appl. Microb. Biotech., 77: 1345-1350.
    PubMed  |  
  162. Chen, G., M. Yang, Y. Song, Z. Lu and J. Zhang et al., 2008. Comparative analysis on microbial and rat metabolism of ginsenoside Rb1 by by high-performance liquid chromatography coupled with tandem mass spectrometry. Biomed. Chromatogr., 22: 79-785.
    PubMed  |  
  163. Chen, G., M. Yang, S. Tao, Z. Lu and J. Zhang et al., 2008. Comparative analysis on microbial and rat metabolism of the total saponins from Panax notoginseng by HPLC-ESI-MS/MS. Nat. Prod. Commun., 3: 661-668.
  164. Zheng, J.H. and D.A. Guo, 2007. Modern Research of Rhubarb. Beijing University of Medical Sciences and Peking Union Medical College Press, Beijing, China.
  165. Zhao, J., S.H. Guan, X.B. Chen, W. Wang, M. Ye and D.A. Guo, 2007. Two new compounds derived from bufalin. Chin. Chem. Lett., 18: 1616-1618.
  166. Zhao, H.Y., J. Han, B.R. Wang and D.A. Guo, 2007. Three new 8-γ,γ-dimethylally flavonoids from the aerial parts of Epimedium koreanum. Helv. Chim. Acta, 90: 2186-2195.
  167. Zhang, Y.S., Q.Y. Zhang, L.Y. Li, B. Wang and Y.Y. Zhao and D.A. Guo, 2007. Simultaneous determination and pharmacokinetic studies of dihydromyricetin and myricetin in rat plasma by HPLC-DAD after orally administrating the decoction of Ampelopsis grossedentata. J. Chromatogr. B, 860: 4-9.
  168. Zhang, J., H. Guo, Y. Tian, P. Liu, N. Li, J. Zhou and D.A. Guo, 2007. Biotransformation of 20(S)-protopanaxatriol by Mucor spinosus and the cytotoxic structure activity relationships of the transformed products. Phytochemistry, 68: 2523-2530.
    PubMed  |  
  169. Ye, M., J. Han, H. Chen, J. Zheng and D.A. Guo, 2007. Analysis of phenolic compounds in Rhubarbs using liquid chromatography coupled with electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrometry, 18: 82-91.
    CrossRef  |  
  170. Yang, M., X.M. Wang, S.H. Guan, J.M. Xia, J.H. Sun, H. Guo and D.A. Guo, 2007. Characterization of triterpenoids in the fruit bodies of Ganoderma lucidum by high peformance liquid chromatography with electrospray ionization tandem mass spectrometry. J. Am. Soc Mass Spectrom., 18: 927-939.
  171. Yang, M., W. Wang, J. Sun, Y.Z. Y. Liu, H. Liang and D.A. Guo, 2007. Characterization of phenolic compounds in the crude extract of Hedysarum multijugum by high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Sp., 21: 3833-3841.
  172. Xu, M., Z.C. Zhang, G. Fu, S.F. Sun and J.H. Sun et al., 2007. Liquid chromatography-tandem mass spectrometry analysis of protocatechuic aldehyde and its phase I and II metabolites in rat. J. Chromatogr. B, 856: 100-107.
    PubMed  |  
  173. Xu, M., Z.C. Zhang, G. Fu, S.F. Sun and J.H. Sun et al., 2007. Comparison of rat tissue distribution after oral administration of salvianolic acid B with that of total phenolic acids from Salvia miltiorrhiza by high performance liquid chromatography. Biomed. Chromatography, 21: 1052-1063.
  174. Xu, M., H. Guo, J. Han, S.F. Sun and AH. Liu et al., 2007. Structural characterization of metabolites of salvianolic acid B from Salvia miltiorrhiza in normal and antibiotic-treated rats by liquid chromatography-mass spectrometry. J. Chromatogr. B., 858: 184-198.
  175. Wang, X.M., S.H. Guan, R.X. Liu, J.H. Sun and Y. Liang et al., 2007. HPLC determination of four triterpenoids in rat urine after oral administration of total triterpenoids from Ganoderma lucidum. J. Pharm. Biomed Anal., 43: 1185-1190.
    CrossRef  |  
  176. Wang, X.M., R.X. Liu, J.H. Sun, S.H. Guan and M. Yang et al., 2007. High-performance liquid chromatographic method for the determination and pharmacokinetic studies of the four triterpenoids in rat plasma after oral administartion of Ganoderma lucidum extract. Biomed. Chromatogr., 21: 389-396.
  177. Wang, W., J. Liu, M. Yang, R. Liu and W. Wang et al., 2007. Isolation and structure elucidation of heteroclitalactones G-P from Kadsura heteroclite. Magn. Reson. Chem., 45: 522-526.
  178. Sun, J.H., M. Yang, X.M. Wang, M. Xu, A.H. Liu and D.A. Guo, 2007. Identification of tanshinones and their metabolites in rat bile after oral administartion of TTE-50, a standardized extract of Salvia miltiorrhiza by HPLC-ESI-DAD-MSn. J. Pharm. Biomed Anal., 44: 564-574.
    CrossRef  |  
  179. Sun, J., M. Yang, J. Han, X. Ma, M. Xu, P. Liu and D.A. Guo, 2007. Profiling the metabolic difference of seven tanshinones using high-performance liquid chromatography/multi-satge mass spectrometry with data-dependent acquisitions. Rapid Commun. Mass Sp., 21: 2211-2226.
    PubMed  |  
  180. Shao, B., H.Z. Guo, Y.J. Cui, A.H. Liu and H.L. Yu et al., 2007. Simultaneous determination of six major stilbenes and flavonoids in Smilax china by high performance liquid chromatography. J. Pharmaceut. Biomed. Anal., 44: 737-742.
    CrossRef  |  PubMed  |  Direct Link  |  
  181. Shao, B., H. Guo, Y. Cui, M. Ye, J. Han and D. Guo, 2007. Four steroidal saponins from Smilax china and their anti-inflammatory activities. Phytochemistry, 68: 623-630.
    CrossRef  |  
  182. Ma, X.C., J. Zheng, L.J. Wu and D.A. Guo, 2007. Structural determination of three new germacrane-type sesquiterpene alcohols from curdione by microbial transformation. Magn Reson Chem., 45: 90-92.
  183. Ma, X.C., J. Zheng and D.A. Guo, 2007. Microbial biotransformation of dehydrocostuslactone and costunolide by Mucor polymorphosporus and Aspergillus candidus. Enzy Microb. Technol., 40: 1013-1019.
    CrossRef  |  
  184. Ma, X.C., J. Zheng and D.A. Guo, 2007. Highly selective isomerization and dehydrogenation of three major bufadienolides at 3-OH by Fusarium solani. Enzy Microb. Technol., 40: 1585-1591.
    CrossRef  |  
  185. Ma, X.C. and D.A. Guo, 2007. Microbial transformation of three bufadienolides by Penicillium aurantigriseum and its application for metabolite identification in rat. J. Mol. Catalysis B: Enzymatic, 48: 42-50.
    Direct Link  |  
  186. Lu, Z.Q., G.T. Chen, J.Q. Zhang, H.L. Huang, S.H. Guan and D.A. Guo, 2007. Four new lanostane triterpenoids from Euphorbia humifusa. Helv. Chim. Acta, 90: 2245-2250.
  187. Liu, P., H. Guo, W. Wang, J. Zhang and N. Li et al., 2007. Cytotoxic diterpenoids from the bark of Pseudolarix kaempferi and their structure-activity relationships. J. Nat. Prod., 70: 533-537.
    PubMed  |  
  188. Liu, A.H., Y.H. Lin, M. Yang, H. Guo, S.H. Guan, J.H. Sun and D.A. Guo, 2007. Development of the fingerprints for the quality of the roots of Salvia miltiorrhiza and its related preparations by HPLC and LC-MS(n). J. Chromatogr B, 846: 32-41.
    CrossRef  |  
  189. Liu, A.H., Y. Lian, Y.H. Lin, W.Y. Wu, J.H. Sun and D.A. Guo, 2007. Detection, characterization and identification of phenolic acids in Danshen using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry. J. Chromatogr. A, 1161: 170-182.
    PubMed  |  Direct Link  |  
  190. Lai, X., Y. Zhao, H. Liang, Y. Bai, B. Wang and D. Guo, 2007. SPE-HPLC method for the determination of four flavonols in rat plasma and urine after oral administration of Abelmoschus manihot extract. J. Chromatogr B Anal. Technol. Biomed Life Sci., 852: 108-114.
    CrossRef  |  
  191. Huang, H.L., Z.Q. Lu, G.T. Chen, J.Q. Zhang, W. Wang, M. Yang and D.A. Guo, 2007. Phenylpropanoid-substituted catechins and epicatechins from Smilax china. Helv. Chim. Acta, 20: 1751-1757.
  192. Han, J., Y. Horie, S. Miura, Y. Akiba and J. Guo et al., 2007. Compound Danshen injection improves endotoxin-induced microcirculatory disturbance in rat mesentery. World J. Gastroenterol., 13: 35881-35891.
    PubMed  |  
  193. Han, J., M. Ye, M. Xu, J. Sun, B. Wang and D. Guo, 2007. Characterization of flavonoids in the Chinese herbal medicine HuangQin by liquid chromatography coupled with electrospray ionization mass spectrometry. J. Chromatogr. B, 848: 355-362.
    CrossRef  |  
  194. Han, J., M. Ye, H. Guo, M. Yang, B.R. Wang and D.A. Guo, 2007. Analysis of multiple constituents in a Chinese herbal preparation Shuang-Huang-Lian oral liquid by HPLC-DAD-ESI-MSn. J. Pharm. Biomed Anal., 44: 430-438.
    CrossRef  |  
  195. Guo, H., A.H. Liu, M. Ye, M. Yang and D.A. Guo, 2007. Characterization of phenolic compounds in the fruits of Forsythia suspensa by high peformance liquid chromatography with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 21: 715-729.
    CrossRef  |  
  196. Guo, H., A.H. Liu, L. Li and D.A. Guo, 2007. Simultaneous determination of twelve major constituents in Forsythia suspensa by high peformance liquid chromatography. J. Pharm. Biomed Anal., 43: 1000-1006.
    CrossRef  |  
  197. Guan, S.H., M. Yang, Z.M. Zhang, X.M. Wang, X. Liu, J.M. Xia and D.A. Guo, 2007. Structure elucidation and complete NMR spectral assignments of three new lanostanoid triterpenes with unprecedented D16,17 double bond from Ganoderma lucidum. Magn. Reson. Chem., 45: 789-791.
  198. Chen, G., M. Yang, Z. Lu, J. Zhang and H. Huang et al., 2007. Microbial transformation of three 20(S)-protopanaxatriol type saponins by Absidia coerulea. J. Nat. Prod., 70: 1203-1206.
    Direct Link  |  
  199. Athanasiou, A., P.A. Smith, S. Vakilpour, N.M. Kumaran and A.E. Turner et al., 2007. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: How vanilloids cause non-vanilloid receptor mediated cell death. Biochem. Biophys. Res. Commun., 354: 50-55.
    PubMed  |  Direct Link  |  
  200. Zhan, J., H. Guo, L. Ning, Y. Zhang and D. Guo, 2006. Efficient preparation of derivatives of resibufogenin using microbial catalytic technique. Planta Med., 72: 346-350.
    Direct Link  |  
  201. Ye, M., H. Guo, H. Guo, J. Han and D. Guo, 2006. Simultaneous determination of cytotoxic bufadienolides in the Chinese medicine ChanSu by high-performance liquid chromatography coupled with photodiode array and mass spectrometry detections. J. Chromatogr. B, 838: 86-95.
    CrossRef  |  
  202. Yang, S.H., H.Z. Guo, D.A. Guo and J.H. Zheng, 2006. Chemical constituents of Cassia obtussifolia hairy roots. China J. Chin. Mater Med., 31: 217-219.
  203. Yang, M., A. Liu, S. Guan, J. Sun, M. Xu and D. Guo, 2006. Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom., 20: 1266-1280.
    CrossRef  |  Direct Link  |  
  204. Yan, Y.Q., D.A. Guo, Y.K. Li, C.E. Wang, Q. Xu et al., 2006. Approaches and Methodologies in TCM Modern Research. Chemical Industry Press, Beijing, China.
  205. Xin, X., Y. Liu, M. Ye, H. Guo and D. Guo, 2006. Microbial transformation of glycyrrhetinic acid by Mucor polymorphosporus. Planta Med., 72: 156-161.
    Direct Link  |  
  206. Wu, W.Y., H.Z. Guo, G.Q. Qu, J. Han and D.A. Guo, 2006. Mechanisms of pseudolaric acid B-induced apoptosis in Bel-7402 cell lines. Am. J. Chin. Med., 34: 887-889.
    PubMed  |  
  207. Wei, W., X. Ma, P. Liu, R. Liu, S. Guan and D. Guo, 2006. Two new dibenzylbutyrolactone type lignans from the stems of Kadsura heteroclite. Nat. Prod. Commun., 1: 109-112.
  208. Wei, W., J. Liu, X. Ma, P. Liu and M. Yang et al., 2006. Three New cyclolanostane triterpenoids from the Stems of Kadsura heteroclita. Helv Chim. Acta, 89: 1888-1893.
  209. Wei, W., J. Liu, M. Yang, X. Wang, J. Sun, R. Liu and D. Guo, 2006. Simultaneous determination of schisanlactone E, nigranoic acid, schisandronic acid, heteroclitalactones A and F and d-epigalbacin in Kadsura heteroclita by HPLC-DAD method. Chromatographia, 64: 297-302.
  210. Wang, X.M., M. Yang, S.H. Guan, R.X. Liu, J.M. Xia, K.S. Bi and D.A. Guo, 2006. Quantitative determination of six major triterpenoids in Ganoderma lucidum and related species by high performance liquid chromatography. J. Pharm. Biomed Anal., 41: 838-844.
    CrossRef  |  PubMed  |  Direct Link  |  
  211. Wang, W., J. Liu, R. Liu, Z. Xu and M. Yang et al., 2006. Four new lignans from the stems of Kadsura heteroclite. Planta Med., 72: 284-288.
  212. Wang, W., J. Liu, J. Han, Z. Xu and R. Liu et al., 2006. New triterpenoids from Kadsura heterioclita and their cytotoxic activity. Planta Med., 72: 450-457.
  213. Wang, Q., R.X. Liu, H.Z. Guo, Z.N. Zhu, K.S. Bi and D.A. Guo, 2006. The influence of processing onthechemical constituents of Paeony roots. China J. Chin. Mater. Med., 31: 1418-1421.
  214. Wang, Q., H. Yang, W. Liu, X. Feng and L. Zhang et al., 2006. Determination of paeoniflorin in rat plasma by a liquid chromatography-tandem mass spectrometry method coupled with solid-phase extraction. Biomed. Chromatogr., 20: 173-179.
    CrossRef  |  Direct Link  |  
  215. Ma, X.C., M. Ye, L.J. Wu and D.A. Guo, 2006. Microbial transformation of curdione by Mucor spinosus. Enzyme Microb. Tech., 38: 367-371.
    CrossRef  |  
  216. Ma, X.C., L.J. Wu and D.A. Guo, 2006. Microbial transformation of dehydrocostuslactone by Mucor polymorphosporus. J. Asi Nat. Prod. Res., 8: 713-718.
    PubMed  |  
  217. Liu, R.X., Y.J. Cui and D.A. Guo, 2006. Phase II reactions of dalbergia odorifera total flavornoids in rats. World Sci. Tech. Mod. Tradi Chin. Mat. Med., 8: 87-97.
  218. Liu, R.X., M. Ye and D.A. Guo, 2006. Approaches and methods for the quality control of traditional Chinese medicine. Chin. J. Nat. Med., 4: 332-337.
  219. Liu, R., W. Wang, Q. Wang, K. Bi and D. Guo, 2006. Identification and determination of major flavonoids in rat urine by HPLC-UV and HPLC-MS methods following oral administration of Dalbergia odorifera extract. Biomed. Chromatogr., 20: 101-108.
    CrossRef  |  Direct Link  |  
  220. Liu, P., H. Guo, Y. Tian, Q. Wang and D. Guo, 2006. Benzoic acid allopyranoside from the bark of Pseudolarix kaempferi. Phytochemistry, 67: 1395-1398.
    CrossRef  |  
  221. Liu, A.H., Y.H. Lin, L. Li, M. Yang, J.H. Sun and D.A. Guo, 2006. High performance liquid chromatographic method for the quantification of tanshinones in fufang danshen tablet. J. Pharmacy Pharm. Sci., 9: 1-9.
  222. Liu, A.H., L. Li, M. Xu, Y.H. Lin, H.Z. Guo and D.A. Guo, 2006. Simultaneous quantification of six major phenolic acids in the roots of Salvia miltiorrhiza and four related traditional Chinese medicinal preparations by HPLC-DAD method. J. Pharm. Biomed. Anal., 41: 48-56.
    CrossRef  |  
  223. Li, L., Y.X. Sheng, J. Zhang, S.S. Wang and D.A. Guo, 2006. Determination of four active saponins of Panax notoginseng by high-performance liquid chromatography in rat tissues. Biomed. Chromatogr., 20: 327-335.
  224. Li, L., M. Ye, Y. Tian, K. Bi and D. Guo, 2006. Microbial biotransformation of rutaecarpine by Cunninghamella blakesleana lendner. Enzy Microb. Tech., 39: 561-567.
  225. Li, L., M. Ye, K. Bi and D.A. Guo, 2006. Liquid chromatography-tandem mass spectrometry for the identification of L-tetrahydropalmatine metabolites in Penicillium janthinellum and rats. Biomed. Chromatogr., 20: 95-100.
    CrossRef  |  
  226. Guo, D.A. G. Ye and H. Guo, 2006. A new phenolic compound from Paeonia lactiflora. Fitoterapia, 77: 613-614.
  227. Guan, S.H., M. Yang, X. Liu, J.M. Xia, X.M. Wang, H. Jin and D.A. Guo, 2006. Two new lanostanoid triterpenes from the fruit body of Ganoderma lucidum-the major component of SunRecome. Nat. Prod. Commun., 1: 177-181.
  228. Chen, W.F., W.S. Lau, P.Y. Cheung, D.A. Guo and M.S. Wong, 2006. Activiation of insulin-like growth factor I receptor-mediated pathway by ginsenoside Rg1. Br. J. Pharmacol., 147: 542-551.
    Direct Link  |  
  229. Zhang, W., M. Ye, G.Q. Qu, W.Y. Wu, Y.J. Chen and D.A. Guo, 2005. Microbial hydroxylation of cinobufagin by Mucor spinosus. J. Asian Nat. Prod. Res., 7: 225-229.
    CrossRef  |  
  230. Zhang, J.L., Y. He, M. Cui, L. Li, H.L. Yu, G.F. Zhang and D.A. Guo, 2005. Metabolic Studies on the total phenolic acids from the roots of Salvia miltiorrhiza in rats. Biomed. Chromatogr., 19: 51-59.
    CrossRef  |  Direct Link  |  
  231. Zhang, J.L., M. Cui, Y. He, H.L. Yu and D.A. Guo, 2005. Chemical fingerprint and metabolic fingerprint analysis of Danshen injection by HPLC-UV and HPLC-MS methods. J. Pharmaceut. Biomed. Anal., 36: 1029-1035.
    CrossRef  |  
  232. Zhang, J.L., H. Yu, Y. Sheng, L. Li, M. Ye and D.A. Guo, 2005. HPLC determination and pharmacokinetic studies of salvianolic acid B in rat plasma after oral administration of Radix Salviae Miltiorrhizae extract. Biomed. Chromatogr., 19: 15-18.
    CrossRef  |  
  233. Ye, Y., J. Han, D. An, G.Z. Tu and D.A. Guo, 2005. New cytotoxic bufadienolides from the biotransformation of resibufogenin by Mucor polymorphosporus. Tetrahedron, 61: 8947-8951.
    CrossRef  |  
  234. Ye, M., Y. Yan and D.A. Guo, 2005. Characterization of phenolic compounds in the Chinese herbal drug Tu-Si-Zi by liquid chromatography coupled to electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom., 19: 1469-1484.
    CrossRef  |  Direct Link  |  
  235. Ye, M., J. Han, G.Z. Tu, D. An and D.A. Guo, 2005. Microbial hydroxylation of bufalin by Cunninghamella blakesleana and Mucor spinosus. J. Nat. Prod., 68: 625-628.
    CrossRef  |  
  236. Ye, M., D.A. Guo, G. Ye and C.G. Huang, 2005. Analysis of homoisoflavonoids in Ophiopogon japonicus by HPLC-DAD-ESI-MS. J. Am. Soc. Mass Spectrom., 16: 234-243.
    CrossRef  |  
  237. Ye, M. and D.A. Guo, 2005. Substrate specificity for the 12β-hydroxylation of bufadienolides by Alternaria alternata. J. Biotechnol., 117: 253-262.
    CrossRef  |  
  238. Ye, M. and D.A. Guo, 2005. Investigations of taxoids by electrospray and atmospheric pressure chemical ionization with tandem mass spectrometry. Rapid Commun. Mass Spectrom., 19: 818-824.
    CrossRef  |  Direct Link  |  
  239. Ye, M. and D.A. Guo, 2005. Analysis of bufadienolides in the Chinese drug ChanSu by high-performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry. Rapid Commun. Mass. Spectrom., 19: 1881-1892.
    CrossRef  |  Direct Link  |  
  240. Ye, G., M. Ye, D. Guo and C. Huang, 2005. Determination of Homoisoflavonoids in Ophiopogon japonicas by RP-HPLC. Chromatographia, 61: 121-125.
    CrossRef  |  
  241. Yang, S.H., X.F. Liu, D.A. Guo and J.H. Zheng, 2005. The biotransformation of nine active substances by three culture systems of Rheum palmatum. J. Jilin Agric. Univ., 4: 408-412.
  242. Yang, S.H., X.F. Liu, D.A. Guo and J.H. Zheng, 2005. Studies on the effects of phytohormones and elicitors on the growth and anthraquinone production of Cassia obtusifolia hairy roots. Chin. Trad. Herb. Drug, 36: 752-756.
  243. Yang, S.H., X.F. Liu, D.A. Guo and J.H. Zheng, 2005. Effects on callus growth and flavonoids production of Glycurrhiza uralensis. J. Jilin Agric. Univ., 27: 289-292.
  244. Yang, S.H., X.F. Liu, D.A. Guo and J.H. Zheng, 2005. Effect of different carbon resources on the biomass and the amount of anthraquinone production in hairy roots of Rheum palmatum. Chin. Trad. Herb. Drug, 36: 1075-1078.
  245. Yang, S., X.F. Liu, D.A. Guo and J.H. Zheng, 2005. Effect of rare-earth element Eu3+ on callus growth and flavonoids content in Glycyrrhiza uralensis. J. Chin. Crude Drugs, 7: 533-534.
    Direct Link  |  
  246. Yan, L. and D.A. Guo, 2005. Determination of astragaloside IV in rat plasma by liquid chromatography electrospray ionization mass spectrometry. J. Chromatogr. B, 824: 244-248.
  247. Xiang, L., X.H. Liu, G.Q. Fan, Y.X. Cui, L.J. Du, D.A. Guo and J.H. Zheng, 2005. Studies on the chemical constituents in the radix and rhizome of Rheum nanum (II). Chin Trad. Herb. Drug, 36: 1306-1309.
  248. Wang, Z.H., M. Ye, J.B. Xing, Y. He and D.A. Guo, 2005. Distribution of aconitine in acute poisoning rats by HPLC-MS method. Chin. J. Chromatogr., 3: 316-316.
  249. Wang, Z.H., J. Wen, Y. He, J. Xing and D.A. Guo, 2005. Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography. Biomed. Chromatogr., 19: 60-62.
    CrossRef  |  
  250. Wang, Q., R.X. Liu, H.Z. Guo, M. Ye, C.H. Huo, K. Bi and D.A. Guo, 2005. Simultaneous LC determination of major constituents in red and white peony root. Chromatographia, 62: 581-588.
    CrossRef  |  
  251. Tian, Y., H. Guo, J. Han and D.A.A Guo, 2005. Microbial transformation of 20(S)-protopanaxatriol by Mucor spinosus. J. Nat. Prod., 68: 678-680.
    CrossRef  |  
  252. Su, Y.F., Z.X. Zhang, C.Y. Guo and D.A. Guo, 2005. Note: A novel cyanogenic glycoside from Semiaquilegia adoxoides. J. Asian Nat. Prod. Res., 7: 171-174.
    CrossRef  |  
  253. Su, Y., C. Li, Y. Gao, L. Di, X. Zhang and D. Guo, 2005. Acryloylated glucose 3-nitropropanoates from Indigofera kirilowii. J. Nat. Prod., 68: 1785-1786.
    CrossRef  |  Direct Link  |  
  254. Sheng, Y.X., L. Li, Q. Wang, H.Z. Guo and D.A. Guo, 2005. Simultaneous determination of gallic acid, albiflorin, paeoniflorin, ferulic acid and benzoic acid in Si-Wu decoction by high-performance liquid chromatography DAD method. J. Pharmaceut. Biomed. Anal., 37: 805-810.
    CrossRef  |  
  255. Sheng, Y.X. and D.A. Guo, 2005. Comparison of main contents in co-boiled extract and mixed extract after individual boiling of Siwu decoction. Chin. J. Pharm. Anal., 1: 1-4.
  256. Qiusheng, Z., Z. Yuntao, Z. Rongliang, G. Dean and L. Changling, 2005. Effects of verbascoside and luteolin on oxidative damage in brain of heroin treated mice. Pharmazie, 60: 539-543.
    Direct Link  |  
  257. Liu, R.X., Q. Wang, K.S. Bi and D.A. Guo, 2005. Chromatographic fingerprint of Dalbergia odorifera and its application in the identification of the crude drugs of different origins. Acta Pharmaceutica Sinica, 40: 1008-1012.
    Direct Link  |  
  258. Liu, R.X., Q. Wang, H.Z. Guo, L. Li, K.S. Bi and D.A. Guo, 2005. Simultaneous determination of 10 major flavonoids in Dalbergia odorifera by high performance liquid chromatography. J. Pharmaceut. Biomed. Anal., 39: 469-476.
    CrossRef  |  
  259. Liu, R.X., M. Ye, H.Z. Guo, K.S. Bi and D.A. Guo, 2005. Liquid chromatography/electrospray ionization mass spectrometry for the characterization of twenty-three flavonoids in the extract of Dalbergia odorifera. Rapid Commun. Mass Spectrom., 19: 1557-1565.
    CrossRef  |  
  260. Liu, R.X., L. Li, Q. Wang, W. Wang, K.S. Bi and D.A. Guo, 2005. Simultaneous determination of nine flavonoids in Dalbergia odorifera by LC. Chromatographia, 61: 409-413.
    CrossRef  |  
  261. Liu, R.X., D.A. Guo, M. Ye, Q. Wang and J.L. Zhang, 2005. Application of LC/MS in modern research of traditional Chinese medicine. World Sci. Tech. Mod. Tradi. Chin. Mat Med., 7: 33-40.
  262. Liu, R., J. Sun, K. Bi and D.A. Guo, 2005. Identification and determination of major flavonoids in rat serum by HPLC-UV and HPLC-MS methods following oral administration of Dalbergia odorifera extract. J. Chromatogr. B, 829: 35-44.
    CrossRef  |  Direct Link  |  
  263. Li, L., Y. Sheng, J. Zhang and D. Guo, 2005. Determination of four active saponins of Panax notoginseng in rat feces by high-performance liquid chromatography. J. Chromatogr. Sci., 43: 421-425.
    Direct Link  |  
  264. Li, L., J.L. Zhang, Y.X. Sheng, H.Z. Guo, Q. Wang and H.Z. Guo, 2005. Simultaneous quantification of six major active saponins of Panax notoginseng by high-performance liquid chromatography-UV method. J. Pharmaceut. Biomed. Anal., 38: 45-51.
    CrossRef  |  
  265. Han, J., M. Ye, H. Chen, S. Dai and D.A. Guo, 2005. Determination of diterpenoids and flavonoids in Isodon rubescens by LC-ESI-MS-MS. Chromatographia, 62: 203-207.
    CrossRef  |  
  266. Guo, D.A., M. Ye, L.L. Ning, J.X. Zhan and H.Z. Guo, 2005. Microbial Transformation of Natural Products. In: Progress in Natural Products Chemistry, Yu, D.Q. and Y.L. Wu (Eds.). Chemistry Industry Press, Beijing, China, pp: 368-389.
  267. Guan, S.H., I. Sattler, W.H. Lin, D.A. Guo and S. Grabley, 2005. p-aminoacetophenonic acids produced by a mangrove endophyte:  Streptomyces griseus subsp. J. Nat. Prod., 68: 1198-1200.
    CrossRef  |  
  268. Guan, S., S. Grabley, I. Groth, W. Lin, A. Christner, D. Guo and I. Sattler, 2005. Structure determination of germacrane-type sesquiterpene alcohols from an endophyte Streptomyces griseus subsp. Magn. Reson. Chem., 43: 1028-1031.
    CrossRef  |  Direct Link  |  
  269. Fu, H., K. Koike, W. Li, T. Nikaido, W. Lin and D. Guo, 2005. Silenorubicosides A-D, triterpenoid saponins from Silene rubicund. J. Nat. Prod., 68: 754-758.
    CrossRef  |  Direct Link  |  
  270. Zhong, L., P. Li, J. Han, G. Qu and D.A. Guo, 2004. Structure-activity relationships of saponins from Gleditsia sinensis in cytotoxicity and induction of apoptosis. Planta Medica, 70: 797-802.
    CrossRef  |  
  271. Zhang, W., M. Ye, J. Zhan, Y. Chen and D.A. Guo, 2004. Microbial glycosylation of four free anthraquinones by Absidia coerulea. Biotechnol. Lett., 26: 127-132.
    CrossRef  |  
  272. Ye, M., L.L. Ning, J.X. Zhan and D.A. Guo, 2004. Research progress on the biotransformation of triptolides and bufadienolides. J. Beijing. Univ. (Med. Edn.), 1: 82-89.
  273. Ye, M., G.Q. Qu, H.Z. Guo and D.A. Guo, 2004. Specific 12β-hydroxylation of cinobufagin by filamentous fungi. Applied Environ. Microb., 70: 3521-3527.
    CrossRef  |  Direct Link  |  
  274. Ye, M., G.Q. Qu, H.Z. Guo and D.A. Guo, 2004. Novel cytotoxic bufadienolides derived from bufalin by microbial hydroxylation and their structure-activity relationships. J. Steroid Biochem. Mol. Biol., 91: 87-98.
    CrossRef  |  
  275. Wang, Z.H., J.Z. Zhao, J.B. Xing and D.A. Guo, 2004. Determination of strychnine and brucine in biological specimens by RP-HPLC technique. J. Anal. Toxicol., 28: 141-144.
  276. Wang, Z.H., J. Wen, J. Zhang, M. Ye and D.A. Guo, 2004. Simultaneous determination of four bufadienolides in human liver by high-performance liquid chromatography. Biomed. Chromatogr., 18: 318-322.
    CrossRef  |  
  277. Wang, Z.H., D.A. Guo, Y. He, C.H. Hu and J. Zhang, 2004. Quantitative determination of Aconitum alkaloids in blood and urine samples by high-performance liquid chromatography. Phytochem. Anal., 15: 16-20.
    CrossRef  |  
  278. Su, Y.F., X.X. Zhang, J. Yang, Z.J. Guo, J.X. Lv and D.A. Guo, 2004. Studies on the chemical constituents of Indigofera carlesii. Chin. Traditional Herbal Drug, 35: 608-611.
  279. Sheng, Y.X., L. Li, C.S. Wang, Y.Y. Li, G. Ye and D.A. Guo, 2004. Solid-phase extraction-liquid chromatographic method for the determination and pharmacokinetic studies of albiflorin and paeoniflorin in rat serum after oral administration of Si-Wu decoction. J. Chromatogr. B, 806: 127-132.
    CrossRef  |  
  280. Sheng, Y., L. Li, J. Zhang and D.A. Guo, 2004. Simultaneous determination of albiflorin and paeoniflorin in rat urine by solid-phase extraction and high-performance liquid chromatography following oral administration of Si-Wu decoction. Biomed. Chromatogr., 18: 785-790.
    CrossRef  |  
  281. Ren, L.J. and D.A. Guo, 2004. Studies on the chemical constituents of Diomedea albatrus. Chin. Traditional Herbal Drug, 35: 138-140.
  282. Ning, L.L., J. Han, X.Y. Zhang, H.Z. Guo, K.S. Bi and D.A. Guo, 2004. Biotransformation of triptolide and triptonide by cell suspension cultures of Catharanthus roseus. J. Asian Nat. Prod. Res., 6: 93-97.
    CrossRef  |  
  283. Li, L., Y. Sheng, J. Zhang, C. Wang and D.A. Guo, 2004. HPLC determination of four active saponins from Panax notoginseng in rat serum and its application to pharmacokinetic studies. Biomed. Chromatogr., 18: 849-856.
    CrossRef  |  
  284. Li, L., P. Li, M. Ye, L. Zhong and D.A. Guo, 2004. Cytotoxic resibufogenin transformation products from cell suspension cultures of Platycodon grandiflorum. Lett. Org. Chem., 1: 176-178.
    CrossRef  |  
  285. Li, L., J.L. Zhang, Y.X. Sheng, G. Ye, H.Z. Guo and D.A. Guo, 2004. Liquid chromatographic method for determination of four active saponins from Panax notoginseng in rat urine using solid-phase extraction. J. Chromatogr. B, 808: 177-183.
    CrossRef  |  
  286. Han, P., Y.J. Cui, H.Z. Guo and D.A. Guo, 2004. Studies on the chemical component and its activity of Buddleja officinalis. Chin. Traditional Herbal Drug, 35: 1086-1090.
  287. Han, P., Y.J. Cui, H.Z. Guo and D.A. Guo, 2004. Studies on an RP-HPLC fingerprints of crude drugs of Buddleja officinalis Maxim. J. Chin. Mat. Med., 29: 938-941.
  288. Guo, H., K. Koike, W. Li, T. Satou, D.A. Guo and T. Nikaido, 2004. Saponins from the flower buds of Buddleja officinalis. J. Nat. Prod., 67: 10-13.
    CrossRef  |  
  289. Guo, H., K. Koike, W. Li, T. Satou, D.A. Guo and T. Nikaido, 2004. Maltol glucosides from the tuber of Smilax bockii. Phytochemistry, 65: 481-484.
    CrossRef  |  
  290. Zhang, Y., L. Zhang, Y.M. Zhou, Y.J. Zhao, D.A. Guo, Y.X. Zhou and J. Cheng, 2003. Application of yeast gene-chip in study of mechanism of berberine. Chin. J. Integr. Trad. Western Med., 23: 48-53.
  291. Zhan, J.X., Y.X. Zhang, L.L. Ning, M. Ye, H.Z. Guo and D.A. Guo, 2003. Biotransformation of taxol by Pseudomonas aeruginosa. Chin. J. Applied Environ. Biol., 9: 429-432.
  292. Zhan, J.X., Q.F. Wei, C.Q. Shan, J. Han, Y.X. Zhang and D.A. Guo, 2003. Studies on the in vitro antimalarial activity of 4 biotransformed products from artemisinin. China Trop. Med., 3: 17-18.
  293. Zhan, J.X., J.J. Zhong, J.G. Dai, H.Z. Guo, W.H. Zhu, Y.X. Zhang and D.A. Guo, 2003. Microbial transformation of sinenxan A, a rich constituent in callus cultures of Taxus. Acta Pharm. Sin., 38: 555-558.
    PubMed  |  
  294. Zhan, J., Y. Zhang, W. Liu, H. Guo and D.A. Guo, 2003. Directional modifications of resibufogenin by Mucor subtilissimus and Pseudomonas aeruginosa. Biocatal. Biotransform., 21: 141-143.
    CrossRef  |  
  295. Zhan, J., W. Liu, H. Guo, Y. Zhang and D.A. Guo, 2003. Selective dehydrogenation of resibufogenin and cinobufagin at 3-OH by Pseudomonas aeruginosa. Enzyme Microb. Technol., 33: 29-32.
    CrossRef  |  
  296. Ye, M., L. Ning, J. Zhan, H. Guo and D.A. Guo, 2003. Biotransformation of cinobufagin by cell suspension cultures of Catharanthus roseus and Platycodon grandiflorum. J. Mol. Catal. B: Enzymatic, 22: 89-95.
    CrossRef  |  
  297. Ye, M., J.G. Dai and D.A. Guo, 2003. Biotransformation of cantharidin by cell suspension cultures of Platycodon grandiflorus. Chin. Traditional Herbal Drug, 34: 869-871.
    CrossRef  |  
  298. Ye, G., Y.Z. Li, Y.Y. Li, H.Z. Guo and D.A. Guo, 2003. SPE-HPLC method for the determination and pharmacokinetic studies on paeoniflorin in rat serum after oral administration of traditional Chinese medicinal preparation Guan-Xin-Er-Hao decoction. J. Pharmaceut. Biomed. Anal., 33: 521-527.
    CrossRef  |  Direct Link  |  
  299. Ye, G., P. Han, H.Z. Guo and D.A. Guo, 2003. Quantitative determination of paeoniflorin in Guanxin II recipe by SPE-HPLC method. Chin. Traditional Herbal Drug, 34: 919-920.
  300. Ye, G., H. Guo and D.A. Guo, 2003. Studies on the chemical constituents of Guanxi II recipe. Chin. Traditional Herbal Drug, 34: 89-90.
  301. Ye, G., C.S. Wang, Y.Y. Li, H. Ren and D.A. Guo, 2003. Simultaneous determination and pharmacokinetic studies on (3,4-dihydroxyphenyl)-lactic acid and protocatechuic aldehyde in rat serum after oral administration of Radix salviae miltiorrhizae extract. J. Chromatogr. Sci., 41: 327-330.
    CrossRef  |  
  302. Wang, Z.Y., R.Q. Qian, S.H. Guan, X.Z. Feng, D.A. Guo, J.J. Ying and J.F. Lu, 2003. Studies on the free radical mechanism of Guanxin II recipe anti-ischemicmyocardial damage effect. Chin. J. Integr. Trad. West Med., 23: 363-366.
  303. Wang, Z.H., D.A. Guo and C.H. Hu, 2003. Simultaneous determination of brucine and strychnine in human blood by reversed phase high performance liquid chromatography. Chin. J. Chromatogr., 4: 382-384.
  304. Su, Y.F., K. Koike, T. Nikaido, J. Liu, J. Zheng and D.A. Guo, 2003. Conyzasaponins I-Q, nine new triterpenoid saponins from Conyza blinii. J. Nat. Prod., 66: 1593-1599.
    CrossRef  |  Direct Link  |  
  305. Ning, L., X. Jiang, M. Ye, H. Guo, K. Bi and D.A. Guo, 2003. Structural determination and complete NMR spectral assignments of a new diterpenoid obtained from triptonide by biotransformation. Magn. Resonance Chem., 41: 633-635.
    CrossRef  |  Direct Link  |  
  306. Ning, L., J. Zhan, G. Qu, L. Zhong, H. Guo, K. Bi and D.A. Guo, 2003. Biotransformation of triptolide by Cunninghamella blakesleana. Tetrahedron, 59: 4209-4213.
    CrossRef  |  Direct Link  |  
  307. Ning, L., H. Guo, X. Jiang, K. Bi and D.A. Guo, 2003. Biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum. Pure Applied Chem., 75: 389-392.
    CrossRef  |  
  308. Ning, L., G. Qu, M. Ye, H. Guo, K. Bi and D.A. Guo, 2003. Cytotoxic biotransformed products from triptonide by Aspergillus niger. Planta Medica, 69: 804-808.
    CrossRef  |  
  309. Han, J., J.G. Dai, Y.J. Cui, J.X. Zhan, H.Z. Guo and D.A. Guo, 2003. Biotransformation of artemisinin by Catharanthus roseus and Ginkgo biloba cell suspension cultures. Chin. Trad. Herbal Drug, 34: 166-168.
  310. Guo, D.A., 2003. Several key issues in the process of TCM modernization. Chin. Traditional Herbal Drug, 34: 9-11.
  311. Dong, A., M. Ye, H. Guo, J. Zheng and D.A. Guo, 2003. Microbial transformation of ginsenoside Rb1 by Rhizopus stolonifer and Curvularia lunata. Biotechnol. Lett., 25: 339-344.
    CrossRef  |  
  312. Dai, J.G., H.Z. Guo, M. Ye, W.H. Zhu and D.Y. Zhang et al., 2003. Biotransformation of 4(20),11-taxadienes by cell suspension cultures of Platycodon grandiflorum. J. Asian Nat. Prod. Res., 5: 5-10.
    CrossRef  |  
  313. Dai, J., H. Guo, M. Ye, W. Zhu and D. Zhang et al., 2003. Highly regio- and stereo-selective hydroxylation of 4(20), 11-taxadienes by Ginkgo cell suspension cultures. Bioorg. Chem., 31: 345-356.
  314. Chow, L.M.C., C. Chui, J.C.O. Tang, F. Lau and M.Y.C. Yau et al., 2003. Anti-angiogenic potential of Gleditsia sinensis fruit extract. Int. J. Mol. Med., 12: 269-273.
    PubMed  |  Direct Link  |  
  315. Zhang, L., Y. Zhang, Y.M. Zhou, S. An, D.A. Guo, Y.X. Zhou and L.W. Zeng, 2002. Analysis of gene expressionof Saccharomyces cerevisiae cells after treatment by antifungal agent. Progr. Biochem. Biophys., 29: 538-542.
  316. Zhan, J.X., Y.X. Zhang, H.Z. Guo, J. Han, L.L. Ning and D.A. Guo, 2002. Microbial metabolism of artemisinin by Mucor polymorphosporus and Aspergillus niger. J. Nat. Prod., 65: 1693-1695.
    CrossRef  |  
  317. Zhan, J., H. Guo, J. Dai, Y. Zhang and D.A. Guo, 2002. Microbial transformations of artemisinin by Cunninghamella echinulata and Aspergillus niger. Tetrahedron Lett., 43: 4519-4521.
    CrossRef  |  Direct Link  |  
  318. Ye, M., J. Han, H. Guo and D.A. Guo, 2002. Structural determination and complete NMR spectral assignments of a new bufadienolide glycoside. Magnet. Resonance Chem., 40: 786-788.
    CrossRef  |  Direct Link  |  
  319. Ye, M., J. Dai, H. Guo and D.A. Guo, 2002. Glucosylation of cinobufagin by cultured suspension cells of Catharanthus roseus. Tetrahedron Lett., 43: 8535-8538.
    CrossRef  |  Direct Link  |  
  320. Xiang, L., G. Fan, J. Li, H. Kang, Y. Yan, J. Zheng and D.A. Guo, 2002. The application of an artificial neural network in the identification of medicinal rhubarbs by near-infrared spectroscopy. Phytochem. Anal., 13: 272-276.
    CrossRef  |  Direct Link  |  
  321. Wang, L.D., D.Y. Qiu, J.Y. Chen, Y.F. Han, J.H. Zheng and D.A. Guo, 2002. Callus cultures of Annona squamosa for the production of Annonaceous acetongenins. J. Asian Nat. Prod. Res., 4: 171-174.
  322. Su, Y., K. Koike, D.A. Guo, J. Jia, J. Liu, J. Zheng and T. Nikaido, 2002. Three new labdane diterpenoid glycoside from Conyza blinii. Heterocycles, 56: 265-271.
  323. Liu, Y., M. Ye, H.Z. Guo, Y.Y. Zhao and D.A. Guo, 2002. New thiophenes from Echinops grijisii. J. Asian Nat. Prod. Res., 4: 175-178.
    CrossRef  |  
  324. Liu, Y., G. Ye, Y.J. Cui, A.Y. Zhang, Y.Y. Zhao and D.A. Guo, 2002. Studies on the chemical constituents of the aerial parts of Echinops grijisii. Chin. Trad. Herb Drug, 33: 18-20.
  325. Li, L.X., Y.F. Su, X.F. Liu and D.A. Guo, 2002. Biotransformation of artemisinin by hairy root cultures of Rheum palmatum L. J. Chin. Pharm. Sci., 11: 122-124.
    Direct Link  |  
  326. Gong, Y.J., L.D. Wang, J.H. Zheng and D.A. Guo, 2002. Antifungal activity of 164 ethanolic extracts from traditional Chinese medicines. Chin. Trad. Herb Drug, 33: 42-47.
  327. Dong, A.L., J.H. Zheng, D.A. Guo, Y.P. Duan, C. Qin and G.Q. Fan, 2002. A simple and fast method for the isolation of trace compound notoginsenoside R2 in Panax notoginseng. Chin. J. Chin. Mat. Med., 27: 793-794.
  328. Dai, J.G., Z. Gong and D.M. Zhu et al., 2002. Biotransformation of gastrodin by cell supension cultures of Gatharanthus roseus. Acta Botanica Sinica, 44: 377-378.
  329. Dai, J., Y. Cui, W. Zhu, H. Guo and M. Ye et al., 2002. Biotransformation of 2α, 5α, 10β, 14β-tetraacetoxy-4(20),11-taxadiene by cell suspension cultures of Catharanthus roseus. Planta Medica, 68: 1113-1117.
    CrossRef  |  Direct Link  |  
  330. Dai, J., M. Ye, H. Guo, W. Zhu and D. Zhang et al., 2002. Regio- and stereo-selective biotransformation of 2α, 5α, 10β, 14β-tetra-acetoxy-4(20), 11-taxadiene by Ginkgo cell suspension cultures. Tetrahedron, 58: 5659-5668.
    CrossRef  |  Direct Link  |  
  331. Chow, L.M.C., J.C.O. Tang, I.T.N. Teo, C.H. Chui and F.Y. Lau et al., 2002. Antiproliferative activity of the extract of Gleditsia sinensis Fruit on human solid tumour cell lines. Exp. Chemother., 48: 303-308.
    CrossRef  |  Direct Link  |  
  332. Chan, R.Y., W.F. Chen, A. Dong, D.A. Guo and M.S. Wong, 2002. Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng. J. Clin. Endocrinol. Metab., 87: 3691-3695.
    CrossRef  |  Direct Link  |  
  333. Bo, T., L. Zhong, M. Li, Y. Luo, K. Li, H. Liu and D.A. Guo, 2002. Separation of isoquinoline alkaloids and saponins by microemulsion electrokinetic chromatography with anionic and cationic surfactants. Chromatographia, 56: 709-716.
    CrossRef  |  Direct Link  |  
  334. Zhan, J.X., H.Z. Guo, J.G. Dai, Y.X. Zhang and D.A. Guo, 2001. Biotransformation of gastrodin by Mucor spinosus. J. Chin. Pharm. Sci., 10: 187-189.
    Direct Link  |  
  335. Wang, L.D., Y.Q. Hu, P.F. Tu, Z.W. Wu, J.H. Zheng and D.A. Guo, 2001. Antifungal screening of thirteen crude extracts and compounds from Chinese crude drugs. Chin. Trad. Herb Drug, 32: 241-241.
  336. Su, Y.F., J.S. Liu, D.A. Guo, Q. Li, H.Z. Guo and J.H. Zheng, 2001. Studies on the flavones of Conyza blinii. Chin. Trad. Herb Drug, 32: 496-496.
  337. Su, Y.F., J.S. Liu, D.A. Guo, M.E. Sun, H.Z. Guo and J.H. Zheng, 2001. Saponins from the plants of family composite. World Phytomed., 16: 12-12.
  338. Su, Y.F., D.A. Guo, Y.J. Cui, J.S. Liu and J.H. Zheng, 2001. A new phenolic glycoside and a new trans-clerodane diterpene from Conyza blinii. J. Asian Nat. Prod. Res., 3: 229-233.
    CrossRef  |  
  339. Su, Y.F., D.A. Guo, M.E. Sun, J.H. Zheng, J.S. Liu and S.L. Yang, 2001. Studies on the terpenoids of Conyza blinii. Chin. Trad. Herb Drug, 32: 496-496.
  340. Su, Y., K. Koike, D.A. Guo, J. Liu, J. Zheng and T. Nikaido, 2001. New Apinose-containing triterpenoid saponins from Conyza blinii. Tetrahedron, 57: 6721-6726.
  341. Su, Y., J. Zheng, D.A. Guo and J. Ma, 2001. Phytochemical and bioactive studies on Conyza blinii. J. Chin. Pharm. Sci., 10: 106-108.
  342. Su, Y., D.A. Guo, H. Guo, J. Liu, J. Zheng, K. Koike and T. Nikaido, 2001. Four new triterpenoid saponins from Conyza blinii. J. Nat. Prod., 64: 32-36.
  343. Guo, D.A., 2001. Basics in Traditional Chinese Medicine. China Medical and Pharmaceutical Press, Beijing, China.
  344. Guo, D.A., 2001. Basics in Pharmaceutics of Traditional Chinese Medicine. China Medical and Pharmaceutical Press, Beijing, China.
  345. Guo, D.A., 2001. Basics in Identification of Chinese Crude Drugs. China Medical and Pharmaceutical Press, Beijing, China.
  346. Guo, D.A., 2001. Basics in Chemistry of Traditional Chinese Medicine. China Medical and Pharmaceutical Press, Beijing, China.
  347. Fu, H.Z., K. Koike, Q. Zheng, K. Mitsunaga and Z.H. Jia et al., 2001. Fargosides A-E, triterpenoid saponins from Holboellia fargesii. Chem. Pharm. Bull., 49: 999-1002.
  348. Dong, A., H. Guo, J. Zheng and D.A. Guo, 2001. Biotransformation of ginsenoside Rg1 by microbial organisms. J. Chin. Pharm. Sci., 10: 115-118.
  349. Dai, J.G., D.D. Lu, Y.J. Cui, H.Z. Guo, J.H. Zheng and D.A. Guo, 2001. Biotransformation of gastrodin using cell suspension cultures of Platycodon grandiflorum. Acta Pharm. Sin., 36: 942-943.
  350. Dai, J., H. Guo, D. Lu, W. Zhu, D. Zhang, J. Zheng and D.A. Guo, 2001. Biotransformation of 2α, 5α, 10β, 14β-tetra-acetoxy-4(20), 11-taxadiene by gingko cell suspension cultures. Tetrhedron Lett., 42: 4677-4679.
  351. Zhang, Z.Z., D.A. Guo, C.L. Li, J.H. Zheng, K. Koike, Z.H. Jia and T. Nikaido, 2000. Gaultherins C and D, two new lignans from Gaultheria yunnanensis. Heterocycles, 53: 675-679.
    CrossRef  |  Direct Link  |  
  352. Wang, L.D., L. Yuang, Q.H. He, J.H. Zheng and D.A. Guo, 2000. The effect of three antifungal compounds on the genetic substances of two fungal cells. Acta Pharm. Sin., 35: 860-862.
  353. Wang, L.D., D.A. Guo, Y.Q. Hu, P.F. Tu, Y.J. Gong and J.H. Zheng, 2000. Effect of four antifungal natural products on ultrastructure of Prototheca wickerhamii. J. Beijing Med. Univ., 32: 219-222.
  354. Su, Y.F., J.S. Liu, D.A. Guo and J.H. Zheng, 2000. Studies on chemical constituents of Conyza plants. World Phytomed., 15: 190-190.
  355. Su, Y. and D.A. Guo, 2000. Recent progress in biosynthesis of Rauwolfia alkaloids. J. Chin. Pharm. Sci., 9: 50-54.
    Direct Link  |  
  356. Liu, S.Q., J.H. Zheng, H. Wang, X. Chen, C. Qiu and D.A. Guo, 2000. The variation of flavones and ginkgolides in the ginkgo leaves in different climate zones. Chin. Trad. Herb Med., 31: 424-426.
  357. Guo, H.Z., X.F. Liu, T. Yu, D.A. Guo and J.H. Zheng, 2000. Quantification of astragaloside Ⅳ in yifukang capsule by high performance liquid chromatography. China J. Chin. Mat. Med., 25: 609-609.
  358. Guo, D.A., L.D. Wang, D.Y. Qiu, J.Y. Chen, Y.F. Han and J.H. Zheng, 2000. Callus cultures of Annona squamosa for the production of Annonaceous acetongenins. J. Korean Med. Crops, 8: 64-72.
  359. Guo, D.A., 2000. TCM quality evaluation and fingerprints of TCM injections. Chin. Drug Standard, 4: 5-8.
  360. Dai, J.G. and D.A. Guo, 2000. Research progress and future perspective on the biotechnology of traditional Chinese medicine. J. TCM Modernization, 2: 27-30.
  361. Chang, Z.Z., Y.H. Liu, K.K. Lu, D.A. Guo, X. Shen, S.S. Wang and K. Wang, 2000. The effect of Eu2+ on the growth of hairy roots of Cassia obtusifolia and the production of active constituents. J. Rare Earth, 18: 146-149.
  362. Chang, Z.Z. and D.A. Guo, 2000. Production of free anthraquinones by using hairy root cultures of Cassia obtusifolia as a bioreactor. J. Beijing Med. Univ., 32: 142-144.
  363. Zou, K., Y.Y. Zhao, G.Z. Tu, D.A. Guo, R.Y. Zhang and J.H. Zheng, 1999. A triterpenoid saponin from Albizia julibrissin. J. Asian Nat. Prod. Res., 1: 313-318.
  364. Zheng, J.H. and D.A. Guo, 1999. Pharmacognosy. 3rd Edn., People's Health Publishing House, Beijing, China.
  365. Zhang, Z.Z., Z.H. Jia, K. Koike, T. Nikaido, D.A. Guo and J.H. Zheng, 1999. Four new triterpenoidal saponins acylated with one monoterpenic acid from Gleditsia sinensis. J. Nat. Prod., 62: 740-745.
    CrossRef  |  Direct Link  |  
  366. Zhang, Z.Z., K. Koike, Z.H. Jia, T. Nikaido, D.A. Guo and J.H. Zheng, 1999. Triterpenoidal saponins from Gleditsia sinensis. Phytochemistry, 52: 715-722.
    CrossRef  |  Direct Link  |  
  367. Zhang, Z.Z., K. Koike, Z.H. Jia, T. Nikaido, D.A. Guo and J.H. Zheng, 1999. Triterpenoidal saponins acylated with two monoterpenic acids from Gleditsia sinensis. Chem. Pharm. Bull., 47: 388-393.
    Direct Link  |  
  368. Zhang, Z.Z., K. Koike, Z.H. Jia, T. Nikaido, D.A. Guo and J.H. Zheng, 1999. New saponins from the seeds of Aesculus chinensis. Chem. Pharm. Bull., 47: 1515-1520.
    Direct Link  |  
  369. Zhang, Z.Z., K. Koike, Z.H. Jia, T. Nikaido, D.A. Guo and J.H. Zheng, 1999. Gleditsiosides N-Q, new triterpenoid saponins from Gleditsia sinensis. J. Nat. Prod., 62: 877-881.
    CrossRef  |  
  370. Zhang, Z.Z., D.A. Guo, C.L. Li, J.H. Zheng, K. Koike, Z.H. Jia and T. Nikaido, 1999. Two direpenoids from Gaultheria yunnanensis. J. Nat. Prod., 62: 297-298.
  371. Zhang, Z.Z., D.A. Guo, C.L. Li, J.H. Zheng, K. Koike, Z.H. Jia and T. Nikaido, 1999. Studies on the chemical constituents of Gaultheria yunnanensis (III). China Trad. Herb. Drug, 30: 247-250.
  372. Zhang, Z.Z., D.A. Guo, C.L. Li, J.H. Zheng, K. Koike, Z.H. Jia and T. Nikaido, 1999. Studies on the chemical constituents of Gaultheria yunnanensis (II). China Trad. Herb. Drug, 30: 167-170.
  373. Zhang, Z.Z., D.A. Guo, C.L. Li, J.H. Zheng, K. Koike, Z.H. Jia and T. Nikaido, 1999. Gaultherin A and B, two new lignans from Gaultheria yunnanensis. Phytochemistry, 51: 469-472.
  374. Zhang, Z.Z., D.A. Guo, C.L. Li and J.H. Zheng, 1999. Studies on the antibacterial, anti-inflammatory and analgesic activities of Gaultheria yunnanensishad. Northwest Pharm. J., 14: 60-61.
  375. Zhang, Z., D. Guo, C. Li, J. Zheng, K. Koike, Z. Jia and T. Nikaido, 1999. Two diterpenoids from the roots of Gaultheria yunnanensis. J. Nat. Prod., 62: 297-298.
    CrossRef  |  Direct Link  |  
  376. Xu, L., D. Guo, J. Liu, J. Zheng, K. Koike, Z. Jia and T. Nikaido, 1999. A new trans-clerodane diterpene lactone from Conyza blinii. Heterocycle, 51: 605-609.
  377. Lu, K.K., Z.Z. Chang, B.W. Chen, D.A. Guo, J.H. Zheng and K. Wang, 1999. The effect of rare earth on the growth and morphology of plant cells. J. Rare Earth, 17: 136-138.
  378. Koike, K., Z.H. Jia, T. Nikaido, Y. Liu, Y.Y. Zhao and D.A. Guo, 1999. A novel benzothiophene glycoside from the roots of Echinops grijisii. Org. Lett., 1: 197-198.
  379. Cui, Y., L. Wang, R.A. Norton, J. Zheng and D.A. Guo, 1999. Biotransformation of 24α-methylcholesterol and 24β-methylcholesterol by yeast mutant GL7. J. Asian Nat. Prod. Res., 2: 39-44.
  380. Chang, Z.Z., X. Shen, D.A. Guo, S.S. Wang and J.H. Zheng, 1999. Studies on isolated root culture of Ri-plasmid transformed Cassia obtusifolia. J. Beijing Med. Univ., 31: 117-119.
  381. Zhang, Z.Z., H. Wang, Y.G. Zheng, D.A. Guo and J.H. Zheng, 1998. Chemical constitutes from Gaultheria yunnanensis and their bioactivities. J. Beij. Med. Univ., 30: 77-80.
  382. Zhang, Z.Z., D.A. Guo, C.L. Li and J.H. Zheng et al., 1998. Chemical constituents from Gaultheria yunnanensis (Franch.) Rehd. (I). China Trad. Herb. Drug, 29: 508-511.
  383. Xu, L.P., J.S. Liu, D. Min, S.W. Wang, D.A. Guo and J.H. Zheng, 1998. Studies on the chemical constituents of Conyza blinii (I). China J. Chin. Mat. Med., 23: 293-295.
  384. Xu, L.P., J.S. Liu, D. Min, D.A. Guo and J.H. Zheng, 1998. Studies on the chemical constituents of Conyza blinii (II). China J. Mat. Med., 23: 552-553.
  385. Wang, H., D. Min, Y.G. Zheng, Y.J. Shi, D.A. Guo and J.H. Zheng, 1998. Analysis of volatile constituents from Ocimum basilicum. J. Beij. Med. Univ., 30: 52-54.
  386. Min, D., L.P. Xu, Z.Z. Zhang, F. Xue, D.A. Guo and J.H. Zheng, 1998. Studies on the chemical constituents of Rheum wittrochii（II). Zhongguo Zhong Yao Za Zhi, 23: 486-488.
    Direct Link  |  
  387. Min, D., F. Xue, L.P. Xu, Z.Z. Zhang, D.A. Guo and J.H. Zheng, 1998. Studies on the chemical constituents of Rheum wittrochii (I). China. J. Chin. Mat. Med., 23: 417-424.
  388. Lu, P., K.K. Lu, J.H. Zheng and D.A. Guo, 1998. The effect of rare earth elements on cell and tissue cultures of Coptis chinensis. J. Beij. Med. Univ., 30: 389-391.
  389. Lu, P., J.H. Zheng, D.A. Guo and K.K. Lu, 1998. Quantitative determination of Berberine and jatrorrhizine in Callus of Coptis chinensis. China J. Pharm. Anal., 18: 101-104.
  390. Lu, K.K., Z.Z. Chang, D.Q. Pei, Z.Z. Chang, D.A. Guo and K. Wang, 1998. The effects of rare earth element on the growth of Rhubarb callus. Northwest Pharm. J., 13: 199-200.
  391. Lu, K.K., Z.Z. Chang, B.W. Chen, D.A. Guo, J.H. Zheng and K. Wang, 1998. Influence of rare earth elements on plant cell growth and morphology. J. Rare Earth, 16: 371-374.
  392. Lu, K.K., W.Y. Tong, R. Hu, D.A. Guo, J.H. Zheng and K. Wang, 1998. Studies on the chemical constituents of Rheum callus. China Trad. Herb. Drug, 29: 438-440.
  393. Liu, Y., D. Min, D. Huang, D.A. Guo and J.H. Zheng, 1998. Analysis of volatile constituents from Rheum wittrochii. J. Beij. Med. Univ., 30: 39-40.
  394. Lin, M., D. Min, D. Huang, D.A. Guo and J.H. Zheng, 1998. Quantification of amino acids in different parts of Rheum wittrochii. J. Beij. Med. Univ., 30: 29-30.
  395. Hu, J., P.F. Tu, D.A. Guo and J.H. Zheng, 1998. UV and TLC analytic identification of Genus Rheum. J. China Med. Mat., 21: 284-287.
  396. Han, J.Y., Z.Z. Zhang, Z.H. Peng, D.A. Guo, J.H. Zheng, 1998. Identification and quality analysis of cordyceps sinensis and its mycelium. J. Beij. Med. Univ., 30: 27-38.
  397. Guo, H.Z., Z.Z. Chang, R.J. Yang, D.A. Guo and J.H. Zheng, 1998. Anthraquinones from hairy root cultures of Cassia obtusifolia. Phytochemistry, 43: 1623-1625.
    CrossRef  |  Direct Link  |  
  398. Guo, H.Z., D.A. Guo, X.Y. Fei, Y.J. Cui and J.H. Zheng, 1998. Biotransformation of podophyllotoxin to picropodophyllin by microbes. J. Asian Nat. Prod. Res., 1: 99-102.
    CrossRef  |  Direct Link  |  
  399. Guo, D.A. and J.G. Dai, 1998. Role of biotechnology in the modernization of traditional Chinese medicine. World Phytomed., 13: 257-260.
  400. Cui, Y.J., Y. Muhetar, S.J. Yue, J.H. Zheng and D.A. Guo, 1998. Studies on the volatile constituents of Rhodiola Rosea. J. Pek. Union Med. College, 18: 11-13.
  401. Chang, Z.Z., X. Shen, D.A. Guo, S.S. Wang, L. Kuanke and J.H. Zheng, 1998. Anthroquinone production in hairy root cultures of Rheum wittrochii Lundstr. J. Beij. Med. Univ., 30: 413-415.
    Direct Link  |  
  402. Chang, Z.Z., X. Shen, D.A. Guo, S.S. Wang and J.H. Zheng, 1998. Comparison of anthraquinones in hairy roots, calli and suspension cells of Rheum palmatum. J. Beijing Med. Univ., 30: 500-502.
  403. Chang, Z.Z., L. Liu, D.A. Guo and J.H. Zheng, 1998. Analysis of anthraquinones by HPLC in Rheum tanguticum and Cassia obtussifolia. J. Beij. Med. Univ., 30: 35-38.
  404. Chang, Z.Z., D.A. Guo, X. Sheng, S.S. Wang and J.H. Zheng, 1998. Analysis of anthraquinones in hairy root cultures of Rheum palmatum. Acta Pharm. Sin., 33: 869-872.
  405. Chang, Z.Z., D.A. Guo and J.H.Zheng, 1998. Recent progress on bioactive natural compounds produced by Ri-lasmid transformed plants (I). Chin Trad. Herb. Drug, 29: 775-784.
  406. Chang, Z.Z., D.A. Guo and J.H. Zheng, 1998. Recent progress on bioactive natural compounds produced by Ri-lasmid transformed plants (I). China Trad. Herb. Drug, 29: 705-707.
  407. Chang, Z.Z. and D.A. Guo, R.A. Norton and J.H. Zheng, 1998. Sterol composition and biosynthesis in hairy root cultures of Cassia obtusifolia. China Trad. Herb. Drug, 29: 723-726.
    Direct Link  |  
  408. An, F., S. Yue, D. Guo and J. Zheng, 1998. Determination of salidroside in eight Rhodiola species by TLC-UV spectrometry. China J. Chin. Mat. Med., 23: 43-44.
    PubMed  |  
  409. Tong, Y.S., B.S. McCourt, D.A. Guo, A.T. Mangla and W.X. Zhou et al., 1997. Stereochemical features of C-methylations on the path to Δ24(28)-methylene and Δ24(28)-ethylidene sterols: studies on the recombinant phytosterol methyl transferase from Arabidopsis thaliana. Tetrahedron Lett., 38: 6115-6118.
  410. Nes, W.D., M. Lopez, W. Zhou and D.A. Guo, 1997. Sterol utilization and metabolism by Heliothis zea. Lipids, 32: 1317-1323.
    CrossRef  |  Direct Link  |  
  411. Nes, W.D., D.A. Guo and W. Zhou, 1997. Substrate-based inhibitors of the S-adenosyl-L-methione: Δ24(25)-sterol methyl transferase from Saccharomyces cerevisiae. Arch. Biochem. Biophys., 342: 68-81.
    CrossRef  |  PubMed  |  Direct Link  |  
  412. Lu, K.K., Z.Z. Chang, B.W. Chen, D.A. Guo, J.H. Zheng and K. Wang, 1997. The hormone-like effect of rare earth elements on plant. J. Beij. Med. Univ., 29: 289-291.
  413. Hu, J., P.F. Tu, D.A. Guo and J.H. Zheng, 1997. Studies on the chemical constituents from Rheum qinlingense. Northwest Pharm. J., 12: 153-155.
  414. Guo, D.A., Z.G. Zhang, G.Q. Ye and Z.C. Lou, 1997. Studies on liposoluble constituents from the aerial parts of Siegesbeckia orientalis L. Acta Pharm. Sin., 32: 282-285.
    PubMed  |  
  415. Guo, D.A., Y.J. Cui, H.Z. Guo, J.H. Zheng and W.D. Nes, 1997. The biosynthesis of 24,25-epiminozymosterol and its inhibitory effect on 24,25-sterol methyl transterase. Northwest Pharm. J., 12: 132-133.
  416. Guo, D.A., J. Hu, Y.J. Cui, H.Z. Guo, J.H. Zheng and W.D. Nes, 1997. Biotransformation of 24-methylenecholesterol and sitosterol by yeast mutant GL-7. Northwest Pharm. J., 12: 174-176.
    Direct Link  |  
  417. Guo, D.A., J. Hu, J.H. Zheng, S.A. Ross and W.D. Nes, 1997. Synthesis and characterization of 3-nitrogen substituted inhibitors of (S)-adenosyl-L-methionine: 24(25)-sterol methyl-transferase. J. China Pharm. Sci., 6: 133-137.
  418. Guo, D.A., D. Nichols, W. Zhou, Lopez, Z. Jia, A.T. Mangla and W.D. Nes, 1997. Antifungal Sterol Biosynthesis Inhibitors. In: Subcellular Biochemistry, Volume 28: Cholesterol: Its Metabolism and Function in Biology and Medicine, Brittman, R. (Ed.). Plenum Press, New York, USA., ISBN 978-0-306-45478-3, pp: 89-122.
  419. Fu, H.Z., Z.C. Lou, X.W. Yang, S.Q. Caiv and D.A. Guo, 1997. Studies of chemical constituents from Siegesbeckia pubescens Makino (I). China Trad. Herb. Drug, 5: 259-262.
  420. Zhou, W., D.A. Guo and W.D. Nes, 1996. Stereochemistry of hydrogen migration from C-24 to C-25 during biomethylation in ergosterol biosynthesis. Tetrahedron Lett., 37: 1339-1342.
    CrossRef  |  
  421. Venkatramesh, M., D.A. Guo, Z. Jia, W.D. Nes, 1996. Mechanism and structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine: δ24(25)-sterol methyl transferase from Saccharomyces cerevisiae. Biochim. Biophys. Acta, 1299: 313-324.
    PubMed  |  
  422. Venkatramesh, M., D.A. Guo, J.G. Harman and W.D. Nes, 1996. Sterol specificity of the Saccharomyces cerevisiae ERG6 gene product expressed in Escherichia coli. Lipids, 31: 373-377.
    PubMed  |  
  423. Short, J.D., D.A. Guo, J.A. Svoboda and W.D. Nes, 1996. Mechanistic and metabolic studies of sterol 24, 25-double bond reduction in Manduca sexta. Arch. Insect Biochem. Physiol., 31: 1-22.
    CrossRef  |  
  424. Nes, W.D. and D.A. Guo, 1996. Rational design of antifungal agents. Information, 7: 866-868.
  425. Jia, Z.H., W. Zhou, D.A. Guo and W.D. Nes, 1996. Synthesis of rationally designed mechanism-based inactivators of the (S)-adenosyl-L-methionine: Δ24(25)-sterol methyl transferase. Syn. Commun., 26: 2758-2765.
    CrossRef  |  Direct Link  |  
  426. Guo, D.A., Z.H. Jia and W.D. Nes, 1996. Phytosterol biosynthesis: Isotope effects associated with biomethylation formation to 24-alkene sterol isomers. Tetrahedron Lett., 37: 6823-6826.
    CrossRef  |  Direct Link  |  
  427. Guo, D.A., Z.H. Jia and W.D. Nes, 1996. Mechanism of hydrogen migration from C-24 to C-25 during phytosterol biomethylation. J. Amer. Chem. Soc., 118: 8507-8508.
  428. Chang, Z.Z., K.K. Lu, D.A. Guo, J.H. Zheng and K. Wan, 1996. Hairy root cultures of Rheum palmatum and Cassia obtussifolia. J. Beij. Med. Univ., 28: 326-330.
  429. Lou, Z.C., D.A. Guo, S.H. Li and L.W. Shi, 1995. Studies on Loulu Crude Drugs. In: Species Systematization and Quality Evaluation of Commonly used Traditional Chinese Crude Drug, Lou, Z.C., B. Qin and D.A. Guo (Eds.). Beijing University of Medical Sciences and Peking Union Medical College Press, Beijing, China, pp: 639-709.
  430. Lou, Z.C., B. Qin and D.A. Guo, 1995. Species Systematization and Quality Evaluation of Commonly Used Traditional Chinese Crude Drugs. Beijing University of Medical Sciences and Peking Union Medical College Press, Beijing, China.
  431. Guo, D.A., M. Venkatramesh and W.D. Nes, 1995. Developmental regulation of sterol biosynthesis in Zea mays. Lipids, 30: 203-219.
    CrossRef  |  
  432. Guo, D.A. and W.D. Nes, 1995. Synthesis of rationally designed inhibitors of the S-adenosyl-L-methione: Δ24(25) -sterol methyl transferase. Syn. Commun., 25: 2623-2630.
  433. Ba, A.S., D.A. Guo, R.A. Norton, S.A. Phillips and W.D. Nes, 1995. Developmental differences in the sterol composition of Solenopsis invicta. Arch. Insect Biochem. Physiol., 29: 1-9.
    CrossRef  |  
  434. Guo, D.A., Z.C. Lou and Z.A. Liu, 1994. Studies on the volatile oil from the roots of Echinops grijisii, China. J. Chin. Mat. Med., 19: 100-100.
  435. Guo, D.A., S.H. Li and Z.C. Lou, 1994. Morphological and histilogical studies on Chinese crude drug Loulu. J. Chin. Pharm. Sci., 3: 18-30.
  436. Guo, D.A., X.Y Zhao and Z.C. Lou, 1993. The determination of scopolamine in zhichuangling injection. Chin Patent Med., 15: 44-44.
  437. An, F., S.J. Yue, D.A. Guo and Z.C. Lou, 1993. Resource investigation of Rhodiola plants in Sichuan Province China. J. Chin. Mat. Med., 18: 455-455.
  438. Guo, D.A., Z.C. Lou, C.Y. Gao, D. Wang and H.Y. Zhang, 1992. Studies on the lipophilic constituents of Rhaponticum uniflorum. Chin Trad Herb Drug, 23: 176-178.
  439. Guo, D.A., Z.C. Lou, C.Y. Gao and D. Wang, 1992. Studies on the chemical constituents of Echinops grijisii. Chin Trad Herb Drug, 23: 512-514.
  440. Guo, D.A., Z.A. Liu and Z.C. Lou, 1992. Constituents of Chinese drug fangfeng, the root of Saposhnikovia divaricata. J. China Pharm. Sci., 1: 81-83.
  441. Guo, D.A., Y.J. Cui, Z.C. Lou, C.Y. Gao and L.R. Huang, 1992. Studies on the chemical constituents of Echinops grijisii. Chin Trad Herb Drug, 23: 3-5.
  442. Guo, D.A., X.Y. Liu, L. Qiao, C.Y. Gao and Z.C. Lou, 1992. Chemical constituents of Echinops talassicus roots. J. Chinies Pharma. Sci., 1: 82-84.
    Direct Link  |  
  443. Guo, D.A. and Z.C. Lou, 1992. Herbalogical study on Chinese drug Loulu. China J. Mat. Med., 17: 579-581.
  444. Guo, D.A., Z.C. Lou, C.Y. Gao, L. Qiao and J.R. Peng, 1991. Phytoecdysteroids of Rhaponticum uniflorum. Yao Xue Xue Bao, 26: 442-446.
    PubMed  |  
  445. Guo, D.A. and Z.C. Lou, 1991. Separation and quantitative determination of three phytoecdysteroids in rhaponticum uniflorum by high performance liquid chromatograghy. J. Chin. Pharm. Sci., 1: 60-66.
    Direct Link  |  
  446. Gao, C.Y., D.A. Guo, L. Qiao, W.Y. He and Z.C. Lou, 1991. NMR study on the structure of a new phytosteroid. China J. Spectro, 8: 379-380.