Dr. Shaoyong  Ke
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Dr. Shaoyong Ke

Research Scientist
Hubei Academy of Agricultural Sciences, China

Highest Degree
Ph.D. in Applied Chemistry from East China University of Science & Technology, China

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Area of Interest:

Applied Chemistry
Drug Discovery
Multicomponents Reaction
Organic Chemistry

Research Publications in Numbers


Selected Publications

  1. Li, S., H. Li, C. Chen, X. Yue, X. Cao and S. Ke, 2013. Novel aroylhydrazine-amide derivatives bearing pyridine core: synthesis, characterisations and selective colorimetric recognition properties. Supramol. Chem., 25: 384-392.
    CrossRef  |  
  2. Ke, S., Z.G. Zhang, T. Long, Y. Liang and Z.W. Yang, 2013. Novel salicylamide derivatives incorporating neonicotinoid pharmacophore: Design, synthesis, characterization and biological evaluation. Med. Chem. Res., 22: 3621-3628.
    CrossRef  |  
  3. Ke, S., Y. Wei, Z. Yang, K. Wang, Y. Liang and L. Shi, 2013. Novel cycloalkylthiophene-imine derivatives bearing benzothiazole scaffold: Synthesis, characterization and antiviral activity evaluation. Bioorg. Med. Chem. Lett., 23: 5131-5134.
    CrossRef  |  
  4. Ke, S., Y. Wei, L. Shi and Yang Q., Z. Yang, 2013. Synthesis of novel steroid derivatives derived from dehydroepiandrosterone as potential anticancer agents. Anticancer Agents Med. Chem., 13: 1291-1298.
    PubMed  |  
  5. Shi, L., R. Hu, Y. Wei, Y. Liang, Z. Yang and S. Ke, 2012. Anthranilic acid-based diamides derivatives incorporating aryl-isoxazoline pharmacophore as potential anticancer agents: Design, synthesis and biological evaluation. Eur. J. Med. Chem., 54: 549-556.
    CrossRef  |  
  6. Li, S., X. Cao, C. Chen and S. Ke, 2012. Novel salicylic acid-oriented thiourea-type receptors as colorimetric chemosensor: Synthesis, characterizations and selective naked-eye recognition properties. Spectrochim. Acta Part A: Mol. Biomol. Spectrosc., 96: 18-23.
    CrossRef  |  
  7. Ke, S., L. Shi, X. Cao, Q. Yang, Y. Liang and Z. Yang, 2012. Heterocycle-functional gramine analogues: Solvent-and catalyst-free synthesis and their inhibition activities against cell proliferation. Eur. J. Med. Chem., 54: 248-254.
    CrossRef  |  
  8. Ke, S., Y.N. Zhang, W. Shu, Z. Zhang and L. Shi et al., 2011. Structural diversity-guided convenient construction of functionalized polysubstituted butenolides and lactam derivatives. C. R. Chim., 14: 1071-1079.
    CrossRef  |  
  9. Ke, S., X. Cao, Y. Liang, K. Wang and Z. Yang, 2011. Synthesis and biological properties of dihydro-oxadiazine-based heterocyclic derivatives. Mini Rev. Med. Chem., 11: 642-657.
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  10. Cao, X., C. Chen, W. Lu and S. Ke, 2011. Chiralβ-arylalkyl-1 H-1, 2, 4-triazoles as demethylase inhibitors: Biological evaluation and its stereoselective interaction with sterol 14α-demethylase from Penicillium digitatum. Pestic. Biochem. Phys., 99: 189-193.
    CrossRef  |  
  11. Ke, S., T.T. Sun, Z.G. Zhang, Y.N. Zhang, Y. Liang, K. Wang and Z. Yang, 2010. Spirodiclofen analogues as potential lipid biosynthesis inhibitors: A convenient synthesis, biological evaluation and structure-activity relationship. Bull. Korean Chem. Soc., 31: 2315-2321.
    Direct Link  |  
  12. Cao, X.F., T.T. Sun and S. Ke, 2010. Progress in the studies on synthesis and biological properties of butenolide and its derivatives. 30 Chin. J. Org. Chem.,: 1113-1125.
  13. Ke, S.Y., X.H. Qian, F.Y. Liu, N. Wang, Q. Yang and Z. Li, 2009. Novel 4 H-1, 3, 4-oxadiazin-5 (6 H)-ones with hydrophobic and long alkyl chains: Design, synthesis and bioactive diversity on inhibition of monoamine oxidase, chitin biosynthesis and tumor cell. Eur. J. Med. Chem., 44: 2113-2121.
    CrossRef  |  
  14. Ke, S., X. Qian, F. Liu, N. Wang, F. Fan, Z. Li and Q. Yang, 2009. Diacylhydrazine derivatives as novel potential chitin biosynthesis inhibitors: Design, synthesis and structure-activity relationship. Eur. J. Med. Chem., 44: 2985-2993.
    CrossRef  |  
  15. Ke, S., F. Liu, N. Wang, Q. Yang and X. Qian, 2009. 1, 3, 4-Oxadiazoline derivatives as novel potential inhibitors targeting chitin biosynthesis: Design, synthesis and biological evaluation. Bioorg. Med. Chem. Lett., 19: 332-335.
    CrossRef  |  
  16. Ke, S., Z. Li and X. Qian, 2008. 1, 3, 4-Oxadiazole-3 (2 H)-carboxamide derivatives as potential novel class of monoamine oxidase (MAO) inhibitors: Synthesis, evaluation and role of urea moiety. Bioorg. Med. Chem., 16: 7565-7572.
    CrossRef  |  
  17. Ke, S.Y. and S.J. Xue, 2006. Synthesis and herbicidal activity of N-(o-fluorophenoxyacetyl) thioureas derivatives and related fused heterocyclic compounds. Arkivoc, 10: 63-68.
    Direct Link  |  
  18. Xue, S., S. Ke, L. Yan, Z. Cai and Y. Wei, 2005. A trifluoromethyl substituted organoimido derivative of the hexametalate cluster: Synthesis, crystal structure and bioactivity of [Mo 6 O 17(NAr) 2] 2−(Ar= o-CF 3 C 6 H 4). J. Inorg. Biochem., 99: 2276-2281.
    CrossRef  |