Dr. Hsueh-Wei  Chang
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Dr. Hsueh-Wei Chang

Professor
Kaohsiung Medical University, Taiwan


Highest Degree
Ph.D. in Molecular & Cellular Biology from National Tsing Hua University, Taiwan

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Area of Interest:

Biomedical Sciences
100%
Bioinformatics
62%
Genomics
90%
Genetic Diversity
75%
Natural Products
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Yang, C.H., Y.S. Lin, S.H. Moi, L.Y. Chuang and H.W. Chang, 2017. A particle swarm optimization-based approach with local search for predicting protein folding. J. Comput. Biol., 24: 981-994.
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  2. Yang, C.H., S.H. Moi, L.Y. Chuang, S.S.F. Yuan, M.F. Hou, Y.C. Lee and H.W. Chang, 2017. Interaction of MRE11 and clinicopathologic characteristics in recurrence of breast cancer: Individual and cumulated receiver operating characteristic analyses. BioMed Res. Int. 10.1155/2017/2563910.
    CrossRef  |  Direct Link  |  
  3. Yang, C.H., K.C. Wu, H.U. Dahms, L.Y. Chuang and H.W. Chang, 2017. Single nucleotide polymorphism barcoding of cytochrome c oxidase I sequences for discriminating 17 species of Columbidae by decision tree algorithm. Ecol. Evol., 7: 4717-4725.
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  4. Wang, H.M., H.L. Yang, V. Thiyagarajan, T.H. Huang and P.J. Huang et al., 2017. Coenzyme Q0 enhances ultraviolet B-induced apoptosis in human estrogen receptor-positive breast (MCF-7) cancer cells. Integr. Cancer Ther., 16: 385-396.
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  5. Liu, S.Y., I.J. Feng, Y.W. Wu, C.Y. Chen and C.N. Hsiung et al., 2017. Implication for second primary cancer from visible oral and oropharyngeal premalignant lesions in betel‐nut chewing related oral cancer. Head Neck, 39: 1428-1435.
    CrossRef  |  Direct Link  |  
  6. Huang, P.C., C.C. Chiu, H.W. Chang, Y.S. Wang and H.H. Syue et al., 2017. Prdx1-encoded peroxiredoxin is important for vascular development in zebrafish. FEBS Lett., 591: 889-902.
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  7. Farooqi, A.A., C.W. Shu, H.W. Huang, H.R. Wang and Y.T. Chang et al., 2017. TRAIL, Wnt, Sonic Hedgehog, TGFβ and miRNA signalings are potential targets for oral cancer therapy. Int. J. Mol. Sci., Vol. 18. 10.3390/ijms18071523.
    CrossRef  |  Direct Link  |  
  8. Chen, C.J., H.W. Chang, C.H. Yang, H.Y. Chuang and H.S. Yu, 2017. Use of genetic algorithm combinational single-nucleotide polymorphisms could modify the association of blood lead levels and bone matrix density. Epidemiology, 28: S121-S125.
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  9. Chang, Y.T., C.Y. Wu, J.Y. Tang, C.Y. Huang and C.C. Liaw et al., 2017. Sinularin induces oxidative stress-mediated G2/M arrest and apoptosis in oral cancer cells. Environ. Toxicol., 32: 2124-2132.
    CrossRef  |  Direct Link  |  
  10. Chang, Y.T., C.Y. Huang, J.Y. Tang, C.C. Liaw and R.N. Li et al., 2017. Reactive oxygen species mediate soft corals-derived sinuleptolide-induced antiproliferation and DNA damage in oral cancer cells. OncoTargets Ther., 10: 3289-3297.
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  11. Chang, H.W., W.D. Wang, C.C. Chiu, C.H. Chen and Y.S. Wang et al., 2017. Ftr82 is critical for vascular patterning during zebrafish development. Int. J. Mol. Sci., Vol. 18. 10.3390/ijms18010156.
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  12. Chang, H.W., R.N. Li, H.R. Wang, J.R. Liu and J.Y. Tang et al., 2017. Withaferin A induces oxidative stress-mediated apoptosis and DNA damage in oral cancer cells. Front. Physiol., Vol. 8. 10.3389/fphys.2017.00634.
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  13. Yen, C.Y., H.W. Huang, C.W. Shu, M.F. Hou and S.S.F. Yuan et al., 2016. DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers. Cancer Lett., 373: 185-192.
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  14. Yeh, C.C., K.T. Li, J.Y. Tang, H.R. Wang and J.R. Liu et al., 2016. Butanol-partitioned extraction from aqueous extract of Gracilaria tenuistipitata inhibits cell proliferation of oral cancer cells involving apoptosis and oxidative stress. DNA Cell Biol., 35: 210-216.
    CrossRef  |  Direct Link  |  
  15. Yang, J.I., J.Y. Tang, Y.S. Liu, H.R. Wang, S.Y. Lee, C.Y. Yen and H.W. Chang, 2016. Roe protein hydrolysates of giant grouper (Epinephelus lanceolatus) inhibit cell proliferation of oral cancer cells involving apoptosis and oxidative stress. BioMed Res. Int. 10.1155/2016/8305073.
    CrossRef  |  Direct Link  |  
  16. Yang, C.H., Y.S. Lin, L.Y. Chuang and H.W. Chang, 2016. Rooted tree optimization algorithm for protein folding prediction. J. Life Sci. Technol., 4: 89-93.
    CrossRef  |  Direct Link  |  
  17. Yang, C.H., Y.D. Lin, L.Y. Chuang and H.W. Chang, 2016. Analysis of high-order SNP barcodes in mitochondrial D-loop for chronic dialysis susceptibility. J. Biomed. Inform., 63: 112-119.
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  18. Shu, C.W., H.T. Chang, C.S. Wu, C.H. Chen and S. Wu et al., 2016. RelA-mediated BECN1 expression is required for reactive oxygen species-induced autophagy in oral cancer cells exposed to low-power laser irradiation. PLoS ONE, Vol. 11. 10.1371/journal.pone.0160586.
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  19. Lin, S.D., S.H. Huang, Y.N. Lin, S.H. Wu and H.W. Chang et al., 2016. Injected implant of uncultured stromal vascular fraction loaded onto a collagen gel: In vivo study of adipogenesis and long-term outcomes. Ann. Plast. Surg., 76: S108-S116.
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  20. Lee, W.C., C.H. Chiu, J.B. Chen, C.H. Chen and H.W. Chang, 2016. Mitochondrial fission increases apoptosis and decreases autophagy in renal proximal tubular epithelial cells treated with high glucose. DNA Cell Biol., 35: 657-665.
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  21. Fu, O.Y., H.W. Chang, Y.D. Lin, L.Y. Chuang, M.F. Hou and C.H. Yang, 2016. Breast cancer-associated high-order SNP-SNP interaction of CXCL12/CXCR4-related genes by an improved Multifactor Dimensionality Reduction (MDR-ER). Oncol. Rep., 36: 1739-1747.
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  22. Chen, C.Y., C.Y. Yen, H.R. Wang, H.P. Yang and J.Y. Tang et al., 2016. Tenuifolide B from Cinnamomum tenuifolium stem selectively inhibits proliferation of oral cancer cells via apoptosis, ROS generation, mitochondrial depolarization and DNA damage. Toxins, Vol. 8. 10.3390/toxins8110319.
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  23. Chang, Y.T., C.Y. Huang, K.T. Li, R.N. Li and C.C. Liaw et al., 2016. Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress and DNA damage. Arch. Oral Biol., 66: 147-154.
    CrossRef  |  Direct Link  |  
  24. Chang, H.W., J.Y. Tang, C.Y. Yen, H.S. Chang and H.W. Huang et al., 2016. Synergistic anti-oral cancer effects of UVC and methanolic extracts of Cryptocarya concinna roots via apoptosis, oxidative stress and DNA damage. Int. J. Radiat. Biol., 92: 263-272.
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  25. Chang, H.W., 2016. Selective killing natural products and drugs in oral cancer treatments. Dent. Res. Manage., Vol. 1, No. 1. .
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  26. Chang, H.S., J.Y. Tang, C.Y. Yen, H.W. Huang and C.Y. Wu et al., 2016. Antiproliferation of Cryptocarya concinna-derived cryptocaryone against oral cancer cells involving apoptosis, oxidative stress and DNA damage. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-1073-5.
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  27. Yen, C.Y., M.F. Hou, Z.W. Yang, J.Y. Tang and K.T. Li et al., 2015. Concentration effects of grape seed extracts in anti-oral cancer cells involving differential apoptosis, oxidative stress and DNA damage. BMC Complement. Altern. Med., Vol. 15. 10.1186/s12906-015-0621-8.
    Direct Link  |  
  28. Yeh, C.C., H.W. Huang, Y.C. Wu, C.C. Chung, S.S.F. Yuan, F.R. Chang and H.W. Chang, 2015. Antioxidant potential of solvent partitioned extraction from aqueous extract of Gracilaria tenuistipitata. Curr. Org. Chem., 19: 39-44.
    CrossRef  |  Direct Link  |  
  29. Yang, C.H., Y.D. Lin, S.J. Wu, L.Y. Chuang and H.W. Chang, 2015. High order gene-gene interactions in eight single nucleotide polymorphisms of Renin-Angiotensin system genes for hypertension association study. BioMed Res. Int. 10.1155/2015/454091.
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  30. Yang, C.H., Y.D. Lin, C.Y. Yen, L.Y. Chuang and H.W. Chang, 2015. A systematic gene-gene and gene-environment interaction analysis of DNA repair genes XRCC1, XRCC2, XRCC3, XRCC4 and oral cancer risk. OMICS: J. Integr. Biol., 19: 238-247.
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  31. Tang, J.Y., R.N. Li, P.H. Chen, H.W. Huang, M.F. Hou and H.W. Chang, 2015. Alternative splicing, DNA damage and modulating drugs in radiation therapy for cancer. Anti-Cancer Agents Med. Chem., 15: 674-680.
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  32. Tang, J.Y., E. Hsi, Y.C. Huang, N.C.H. Hsu and W.C. Yang et al., 2015. Overexpression of autophagy-related 16-Like 1 in patients with oral squamous cell carcinoma. Pathol. Oncol. Res., 21: 301-305.
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  33. Ou-Yang, F., Y.D. Lin, L.Y. Chuang, H.W. Chang, C.H. Yang and M.F. Hou, 2015. The combinational polymorphisms of ORAI1 gene are associated with preventive models of breast cancer in the Taiwanese. BioMed Res. Int. 10.1155/2015/281263.
    CrossRef  |  Direct Link  |  
  34. Lee, W.C., L.C. Li, J.B. Chen and H.W. Chang, 2015. Indoxyl sulfate-induced oxidative stress, mitochondrial dysfunction, and impaired biogenesis are partly protected by vitamin C and N-acetylcysteine. Scient. World J. 10.1155/2015/620826.
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  35. Huang, S.H., Y.N. Lin, S.S. Lee, C.Y. Chai and H.W. Chang et al., 2015. New adipose tissue formation by human adipose-derived stem cells with hyaluronic acid gel in immunodeficient mice. Int. J. Med. Sci., 12: 154-162.
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  36. Huang, I.F., I.C. Lin, P.F. Liu, M.F. Cheng and Y.C. Liu et al., 2015. Lactobacillus acidophilus attenuates Salmonella-induced intestinal inflammation via TGF-β signaling. BMC Microbiol., Vol. 15. 10.1186/s12866-015-0546-x.
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  37. Farooqi, A.A., S.J. Wu, Y.T. Chang, J.Y. Tang and K.T. Li et al., 2015. Activation and inhibition of ATM by phytochemicals: Awakening and sleeping the guardian angel naturally. Arch. Immunol. Ther. Exp., 63: 357-366.
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  38. Farooqi, A.A., R.N. Li, H.W. Huang, M. Ismail and S.F. Yuan et al., 2015. Natural products mediated regulation of oxidative stress and DNA damage in ultraviolet exposed skin cells. Curr. Pharmaceut. Biotechnol., 16: 1078-1084.
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  39. Farooqi, A.A., K.T. Li, S. Fayyaz, Y.T. Chang and M. Ismail et al., 2015. Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress. Tumor Biol., 36: 5743-5752.
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  40. Farooqi, A.A., J.Y. Tang, R.N. Li, M. Ismail and Y.T. Chang et al., 2015. Epigenetic mechanisms in cancer: Push and pull between kneaded erasers and fate writers. Int. J. Nanomed., 10: 3183-3191.
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  41. Chiu, C.C., H.L. Chou, B.H. Chen, K.F. Chang and C.H. Tseng et al., 2015. BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model. BMC Cancer, Vol. 15. 10.1186/s12885-015-1970-x.
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  42. Chang, H.W., S.Y. Chen, L.Y. Chuang and S. Guleria, 2015. Toxicology and disease/cancer therapy in reactive oxygen species-mediated drugs and treatments. Scient. World J. 10.1155/2015/860563.
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  43. Yen, Y.H., A.A. Farooqi, K.T. Li, G. Butt and J.Y. Tang et al., 2014. Methanolic extracts of Solieria robusta inhibits proliferation of oral cancer Ca9-22 cells via apoptosis and oxidative stress. Molecules, 19: 18721-18732.
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  44. Yang, C.H., Y.D. Lin, L.Y. Chuang and H.W. Chang, 2014. Double-bottom chaotic map particle swarm optimization based on chi-square test to determine gene-gene interactions. BioMed Res. Int. 10.1155/2014/172049.
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  45. Yang, C.H., Y.D. Lin, L.Y. Chuang and H.W. Chang, 2014. DBM-PSO-based SNP-SNP interaction of DNA repair genes in simulated breast cancer association study. J. Bioinform. Res. Stud., Vol. 1. .
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  46. Wu, B.J., C.C. Chiu, C.L. Chen, W.D. Wang and J.H. Wang et al., 2014. Nuclear receptor subfamily 2 group F member 1a (nr2f1a) is required for vascular development in zebrafish. PLoS ONE, Vol. 9. 10.1371/journal.pone.0105939.
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  47. Tseng, C.N., Y.T. Chang, H.T. Chiu, Y.C. Chou and H.W. Huang et al., 2014. High-throughput gender identification of penguin species using melting curve analysis. Anim. Biotechnol., 25: 119-127.
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  48. Tseng, C.N., Y.R. Hong, H.W. Chang, T.J. Yu and T.W. Hung et al., 2014. Brefeldin A reduces anchorage-independent survival, cancer stem cell potential and migration of MDA-MB-231 human breast cancer cells. Molecules, 19: 17464-17477.
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  49. Tseng, C.K., C.K. Lin, H.W. Chang, Y.H. Wu and F.L. Yen et al., 2014. Aqueous extract of Gracilaria tenuistipitata suppresses LPS-induced NF-κB and MAPK activation in RAW 264.7 and rat peritoneal macrophages and exerts hepatoprotective effects on carbon tetrachloride-treated rat. PLoS ONE, Vol. 9. 10.1371/journal.pone.0086557.
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  50. Li, R.N., C.J. Wu, Z.J. Yu, H.W. Chang and S.S. Liang, 2014. Networks development between nicotinic chemical probes and Ca9-22 oral cancer cells by general proteomics analyses. Electrophoresis, 35: 2213-2221.
    CrossRef  |  Direct Link  |  
  51. Huang, H.W., Y.A. Chung, H.S. Chang, J.Y. Tang, I.S. Chen and H.W. Chang, 2014. Antiproliferative effects of methanolic extracts of Cryptocarya concinna Hance roots on oral cancer Ca9-22 and CAL 27 cell lines involving apoptosis, ROS induction and mitochondrial depolarization. Scient. World J. 10.1155/2014/180462.
    CrossRef  |  Direct Link  |  
  52. Huang, C.J., S.L. Lian, M.F. Hou, C.Y. Chai, Y.H. Yang, S.F. Lin and H.W. Chang, 2014. SNP 1772 C > T of HIF-1α gene associates with breast cancer risk in a Taiwanese population. Cancer Cell Int., Vol. 14. 10.1186/s12935-014-0087-7.
    CrossRef  |  Direct Link  |  
  53. Farooqi, A.A., S. Fayyaz, M.F. Hou, K.T. Li, J.Y. Tang and H.W. Chang, 2014. Reactive oxygen species and autophagy modulation in non-marine drugs and marine drugs. Mar. Drugs, 12: 5408-5424.
    CrossRef  |  Direct Link  |  
  54. Farooqi, A.A., M.F. Hou, C.C. Chen, C.L. Wang and H.W. Chang, 2014. Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells. Cancer Cell Int., Vol. 14. 10.1186/1475-2867-14-34.
    CrossRef  |  Direct Link  |  
  55. Chuang, L.Y., H.Y. Lane, Y.D. Lin, M.T. Lin, C.H. Yang and H.W. Chang, 2014. Identification of SNP barcode biomarkers for genes associated with facial emotion perception using particle swarm optimization algorithm. Ann. Gen. Psychiatry, Vol. 13. 10.1186/1744-859X-13-15.
    CrossRef  |  Direct Link  |  
  56. Cheng, Y.H., L.Y. Chuang, H.W. Chang and C.H. Yang, 2014. Improved candidate drug mining for Alzheimer's disease. BioMed Res. Int. 10.1155/2014/897653.
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  57. Chen, J.B., L.Y. Chuang, Y.D. Lin, C.W. Liou and T.K. Lin et al., 2014. Genetic algorithm-generated SNP barcodes of the mitochondrial D-loop for chronic dialysis susceptibility. Mitochondrial DNA, 25: 231-237.
    CrossRef  |  Direct Link  |  
  58. Chang, W.C., Y.Y. Fang, H.W. Chang, L.Y. Chuang, Y.D. Lin, M.F. Hou and C.H. Yang, 2014. Identifying association model for single-nucleotide polymorphisms of ORAI1 gene for breast cancer. Cancer Cell Int., Vol. 14. 10.1186/1475-2867-14-29.
    CrossRef  |  Direct Link  |  
  59. Chang, H.W., H.C. Wang, C.Y. Chen, T.W. Hung and M.F. Hou et al., 2014. 5-azacytidine induces anoikis, inhibits mammosphere formation and reduces metalloproteinase 9 activity in MCF-7 human breast cancer cells. Molecules, 19: 3149-3159.
    CrossRef  |  Direct Link  |  
  60. Yen, C.Y., C.Y. Huang, M.F. Hou, Y.H. Yang and C.H. Chang et al., 2013. Evaluating the performance of fibronectin 1 (FN1), integrin α4β1 (ITGA4), syndecan-2 (SDC2), and glycoprotein CD44 as the potential biomarkers of oral squamous cell carcinoma (OSCC). Biomarkers, 18: 63-72.
    CrossRef  |  PubMed  |  Direct Link  |  
  61. Yang, H.P., T.C. Wang, S.J. Wang, S.P. Chen and E. Wu et al., 2013. Recombinant chimeric vaccine composed of PRRSV antigens and truncated Pseudomonas exotoxin A (PE-K13). Res. Vet. Sci., 95: 742-751.
    CrossRef  |  PubMed  |  Direct Link  |  
  62. Yang, C.H., Y.H. Cheng, L.Y. Chuang and H.W. Chang, 2013. Drug-SNPing: An integrated drug-based, protein interaction-based tagSNP-based pharmacogenomics platform for SNP genotyping. Bioinformatics, 29: 758-764.
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  63. Yang, C.H., Y.D. Lin, L.Y. Chuang, J.B. Chen and H.W. Chang, 2013. MDR-ER: Balancing functions for adjusting the ratio in risk classes and classification errors for imbalanced cases and controls using multifactor-dimensionality reduction. PloS One, Vol. 8. 10.1371/journal.pone.0079387.
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  64. Yang, C.H., H.W. Chang, H.Y. Lin and L.Y. Chuang, 2013. Evaluation of antioxidant and antimicrobial activities from 28 Chinese herbal medicines. J. Pharm. Phytochem., 2: 294-305.
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  65. Yang, C., Y. Lin, L. Chaung and H. Chang, 2013. Evaluation of breast cancer susceptibility using improved genetic algorithms to generate genotype SNP barcodes. IEEE/ACM Trans. Comput. Biol. Bioinformat., 10: 361-371.
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  66. Wu, S.J., L.Y. Chuang, Y.D. Lin, W.H. Ho, F.T. Chiang, C.H. Yang and H.W. Chang, 2013. Particle swarm optimization algorithm for analyzing SNP-SNP interaction of renin-angiotensin system genes against hypertension. Mol. Biol. Rep., 40: 4227-4233.
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  67. Tseng, C.N., H.W. Chang, J. Stocker, H.C. Wang and C.C. Lu et al., 2013. A method to identify RNA A-to-I editing targets using I-specific cleavage and exon array analysis. Mol. Cell. Probes, 27: 38-45.
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  68. Tseng, C.N., C.F. Huang, C.L. Cho, H.W. Chang and C.W. Huang et al., 2013. Brefeldin a effectively inhibits cancer stem cell-like properties and mmp-9 activity in human colorectal cancer colo 205 cells. Molecules, 18: 10242-10253.
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  69. Tang, J.Y., L.Y. Chuang, E. Hsi, Y.D. Lin, C.H. Yang and H.W. Chang, 2013. Identifying the association rules between clinicopathologic factors and higher survival performance in operation-centric oral cancer patients using the apriori algorithm. BioMed Res. Int., 10.1155/2013/359634.
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  70. Tang, J.Y., J.C. Lee, Y.T. Chang, M.F. Hou, C.C. Liaw and H.W. Chang, 2013. Long noncoding RNAs-related diseases, cancers, and drugs. Sci. World J., 10.1155/2013/943539.
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  71. Tang, J.Y., J.C. Lee, M.F. Hou, C.L. Wang, C.C. Chen, H.W. Huang and H.W. Chang, 2013. Alternative splicing for diseases, cancers, drugs, and databases. Sci. World J., 10.1155/2013/703568.
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  72. Tang, J.Y., H.W. Chang and J.G. Chang, 2013. Modulating roles of amiloride in irradiation-induced antiproliferative effects in glioblastoma multiforme cells involving akt phosphorylation and the alternative splicing of apoptotic genes. DNA Cell Biol., 32: 504-510.
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  73. Stocker, J., H.W. Huang, H.M. Wang, H.W. Chang and C.C. Chiu, C.L. Cho and C.N. Tseng, 2013. Reduction of RNA A-to-I editing in Drosophila acclimated to heat shock. Kaohsiung J. Med. Sci., 29: 478-483.
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  74. Lee, J.C., M.F. Hou and H.W. Huang, F.R. Chang, C.C. Yeh, J.Y. Tang and H.W. Chang, 2013. Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties. Cancer Cell Int., Vol. 13. 10.1186/1475-2867-13-55.
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  75. Huang, W.H., C.N. Tseng, J.Y. Tang, C.H. Yang, S.S. Liang and H.W. Chang, 2013. RNA editing and drug discovery for cancer therapy. Sci. World J., 10.1155/2013/804505.
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  76. Chuang, L.Y., H.W. Chang, M.C. Lin and C.H. Yang, 2013. Improved branch and bound algorithm for detecting SNP-SNP interactions in breast cancer. J. Clin. Bioinformat., Vol. 3. 10.1186/2043-9113-3-4.
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  77. Chiu, C.C., J.W. Haung, F.R. Chang, K.J. Huang and H.M. Huang et al., 2013. Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways. PloS One, Vol. 8. 10.1371/journal.pone.0064739.
    CrossRef  |  PubMed  |  Direct Link  |  
  78. Chen, K.J., C.K. Tseng, F.R. Chang, J.I. Yang and C.C. Yeh et al., 2013. Aqueous extract of the edible Gracilaria tenuistipitata inhibits hepatitis C viral replication via cyclooxygenase-2 suppression and reduces virus-induced inflammation. PloS One, Vol. 8. 10.1371/journal.pone.0057704.
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  79. Chen, J.B., L.Y. Chuang, Y.D. Lin, C.W. Liou and T.K. Lin et al., 2013. Preventive SNP-SNP interactions in the mitochondrial displacement loop (D-loop) from chronic dialysis patients. Mitochondrion, 13: 698-704.
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  80. Chen, J.B., L.Y. Chuang, Y.D. Lin, C.W. Liou and T.K. Lin et al., 2013. Genetic algorithm-generated SNP barcodes of the mitochondrial D-loop for chronic dialysis susceptibility. Mitochondrial DNA, 10.3109/19401736.2013.796513.
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  81. Chang, H.W., Y.H. Chiu, H.Y. Kao, C.H. Yang and W.H. Ho, 2013. Comparison of classification algorithms with wrapper-based feature selection for predicting osteoporosis outcome based on genetic factors in a Taiwanese women population. Int. J. Endocrinol., 10.1155/2013/850735.
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  82. Chang, H.W., L.Y. Chuang, S. Guleria and S. Yasmin, 2013. Natural products: Bioactivity, biochemistry, and biological effects in cancer and disease therapy. Sci. World J., 10.1155/2013/713480.
    CrossRef  |  Direct Link  |  
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  165. Chang, H.W. and I.M. Shih, 2005. Digital Single-Nucleotide Polymorphism analysis for Allelic Imbalance. In: Pancreatic Cancer: Methods and Protocols, Su, G.H. (Ed.). Springer, USA., pp: 137-141.
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  166. Singer, G., R.J. Kurman, H.W. Chang, S.K. Cho and I.M. Shih, 2002. Diverse tumorigenic pathways in ovarian serous carcinoma. Am. J. Pathol., 160: 1223-1228.
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  167. Chang, Y.C., H.W. Chang, C.B. Liao and Y.C. Liu, 2002. The roles of p53, DNA repair, and oxidative stress in ultraviolet C induction of proliferating cell nuclear antigen expression. Ann. N. Y. Acad. Sci., 973: 384-391.
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  168. Chang, H.W., S.M. Lee, S.N. Goodman, G. Singer and S.K. Cho et al., 2002. Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer. J. Nat. Cancer Inst., 94: 1697-1703.
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  169. Chang, H.W., S. Ali, R.J. Kurman and I.M. Shih, 2002. Detection of allelic imbalance in ascites fluids correlates with cancer status. Clin. Cancer Res., 8: 2580-2585.
  170. Chang, H.W., C.Y. Yen, S.Y. Liu, G. Singer and I.M. Shih, 2002. Genotype analysis using human hair shaft. Cancer Epidemiol. Biomarkers Prev., 11: 925-929.
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  171. Tzang, B.S., Y.C. Lai, M. Hsu, H.W. Chang, C.C. Chang, P.C. Huang and Y.C. Liu, 1999. Function and sequence analyses of tumor suppressor gene p53 of CHO.K1 cells. DNA Cell Biol., 18: 315-321.
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  172. Chang, H.W., Y.C. Lai, C.Y. Cheng, J.L. Ho, S.T. Ding and Y.C. Liu, 1999. UV inducibility of rat proliferating cell nuclear antigen gene promoter. J. Cell. Biochem., 73: 423-432.
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  173. Liu, Y.C., H.W. Chang, Y.C. Lai, S.T. Ding and J.L. Ho, 1998. Serum responsiveness of the rat PCNA promoter involves the proximal ATF and AP-1 sites. FEBS Lett., 441: 200-204.
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