Dr. Mumin Alper Erdogan
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Dr. Mumin Alper Erdogan

Assistant Professor
Department of Physiology, Faculty of Medicine, Katip Celebi University, Izmir, Turkiye

Highest Degree
PostDoc Fellow in Medicine from Izmir Katip Celebi University, Turkiye

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Dr. Mumin Alper Erdogan is working as an Assistant Professor in Izmir Katip Çelebi Uni. in department. of Medical Physiology. He started his Ph.D. in department of Veterinary Physiology in 2009 and graduated from Adnan Menderes University faculty of Veterinary Medicine. For his Ph.D. research project, he worked with Dr. Bulent Ozpolat in MD Anderson Cancer Center at the department of experimental therapeutics about 2 years. His research subjects are focused on studying the role of ion channels, eEF2-kinase (eEF2K) signaling and development of novel therapeutic agents (siRNA-based nano-therapeutics) that target these pathways with his collaboration group at UT MD Anderson Cancer Center. He won two “Young Basic Cancer Investigator” awards from MOKAD and EACR in 2014 and 2016.

Area of Interest:

Animal and Veterinary Sciences
Veterinary Medicine
Veterinary Advances
Veterinary Physiology
Animal Handling

Research Publications in Numbers


Selected Publications

  1. Zorbozan, O., M. Harman, V. Evren, M.A. Erdogan and A. Kilavuz et al., 2018. Infecting glial cells with antimony resistant Leishmania tropica: A new ex-vivo model. Mikrobiyoloji Bulteni, 52: 49-55.
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  2. Uner, A.G., C. Unsal, H. Unsal, M.A. Erdogan and E. Koc et al., 2018. Mice with diet-induced obesity demonstrate a relative prothrombotic factor profile and a thicker aorta with reduced ex-vivo function. Blood Coagulation Fibrinolysis, 29: 257-266.
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  3. Sarikaya, G., G. Coban, S. Parlar, A.H. Tarikogullari and G. Armagan et al., 2018. Multifunctional cholinesterase inhibitors for Alzheimer's disease: Synthesis, biological evaluations and docking studies of o/p‐propoxyphenylsubstituted‐1H‐benzimidazole derivatives. Archiv der Pharmazie, Vol. 351. 10.1002/ardp.201800076.
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  4. Loubidi, M., J. Jouha, Z. Tber, M. Khouili and F. Suzenet et al., 2018. Efficient synthesis and first regioselective C-6 direct arylation of imidazo [2, 1-c][1, 2, 4] triazine scaffold and their evaluation in H2O2-induced oxidative stress. Eur. J. Med. Chem., 145: 113-123.
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  5. Erdogan, M.A., D. Yusuf, J. Christy, V. Solmaz, A. Erdogan, E. Taskiran and O. Erbas, 2018. Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy. BMC Neurol., Vol. 18. 10.1186/s12883-018-1086-4.
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  6. Erdogan, M.A., B.P. Cinar, K.D. Kiilic, T. Cavusoglu and G. Yigitturk et al., 2018. Demonstration of PTZ-induced convulsive-reducing effect of butamirate citrate. NeuroQuantology, 16: 65-69.
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  7. Erdogan, M.A. and O. Erbas, 2018. Ion channels and cancer. FNG Bilim Tıp Dergisi, 4: 49-62.
  8. Erdogan, M.A. and B. Ozpolat, 2018. Targeted silencing of NaV1. 5 channel suppresses cell proliferation and invasion in ovarian cancer cells through inhibition of PI3K/AKT and Integrinβ-1/FAK/Src axis. Cancer Res., Vol. 78. 10.1158/1538-7445.AM2018-1950.
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  9. Erbas, O., M.A. Erdogan, A. Khalilnezhad, V. Solmaz and F.T. Gurkan et al., 2018. Evaluation of long‐term effects of artificial sweeteners on rat brain: A biochemical, behavioral and histological study. J. Biochem. Mol. Toxicol., Vol. 32. 10.1002/jbt.22053.
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  10. Erbas, O., M.A. Erdogan, A. Khalilnezhad, F.T. Gurkan, G. Yigitturk, A. Meral and D. Taskiran, 2018. Neurobehavioral effects of long-term maternal fructose intake in rat offspring. Int. J. Dev. Neurosci., 69: 68-79.
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  11. Bora, S., M.A. Erdogan, G. Yigitturk, O. Erbas and I. Parlak, 2018. The effects of lipid emulsion, magnesium sulphate and metoprolol in amitriptyline-induced cardiovascular toxicity in rats. Cardiovascular Toxicol., 18: 547-556.
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  12. Bora, E.S., M.A. Erdogan and O. Erbas, 2018. Electrophys iological evaluation of oxytocin's effects on bas olateral amygdala. Istanbul Bilim Univ. Florence Nightingale Tip Dergisi, 4: 79-85.
  13. Bircan, H.A., N. Gurbuz, A. Pataer, A. Caner and N. Kahraman et al., 2018. Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer. Lung Cancer, 124: 31-39.
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  14. Taskin, B., M.A. Erdogan, G. Yigitturk, D. Gunenc and O. Erbas, 2017. Antifibrotic effect of lactulose on a methotrexate-induced liver injury model. Gastroenterol. Res. Pract., Vol. 2017. 10.1155/2017/7942531.
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  15. Erdogan, M.A. and O.A. Yilmaz, 2017. Rottlerin and genistein suppress cell proliferation, invasion, cell cycle and induce apoptosis in neuroblastoma cells. Acta Physiol., 221: 49-125.
  16. Erdogan, M.A. and O.A. Yilmaz, 2017. Effects of rottlerin and genistein on proliferation, invas ion and cell death in neuroblastoma cells. Anatomy, 11: S1-S86.
  17. Erdogan, M.A. and O.A. Yilmaz, 2017. 64PEffects of rottlerin and genistein through EF2K on proliferation, invasion and cell cycle/death in neuroblastoma cells. Ann. Oncol., Vol. 28. 10.1093/annonc/mdx361.059.
    CrossRef  |  
  18. Erdogan, M.A. and B. Ozpolat, 2017. Targeting of NaV1. 5 channel in metastatic breast cancer models in vitro and in vivo mice as a novel therapy. Eur. J. Cancer, Vol. 72. 10.1016/S0959-8049(17)30221-6.
    CrossRef  |  
  19. Erdogan, M.A. and B. Ozpolat, 2017. Targeted silencing of elongation factor 2 kinase (EF2K) suppresses invasion, cell proliferation and growth in an orthotopic model of ovarian cancer. Cancer Res., Vol. 77. 10.1158/1538-7445.AM2017-1154.
    CrossRef  |  
  20. Erdogan, M.A., O. Erbas, A. Khalilnezhad, F.T. Gurkan, G. Yigitturk and D. Taskiran, 2016. Induction of behavioral and histological alterations in rats by chronic consuming of artificial sweeteners: A comparative study. Acta Physiol., 218: 20-21.
  21. Bora, S., M.A. Erdogan, G. Armagan, E. Sevgili and T. Dagci, 2016. Vinpocetine and vasoactive intestinal peptide attenuate manganese-induced toxicity in NE-4C cells. Biol. Trace Element Res., 174: 410-418.
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  22. Ashour, A., A. Erdogan, S.N. Alpay, N. Kahraman, E. Yuka, G. Lopez-Berestein and B. Ozpolat, 2015. EF2-kinase (EF2K): A novel molecular target in ovarian and pancreatic cancers. Cancer Res., Vol. 75. 10.1158/1538-7445.AM2015-2642.
    CrossRef  |  
  23. Gonzalez-Villasana, V., C. Rodriguez-Aguayo, T. Arumugam, Z. Cruz-Monserrate and E. Fuentes-Mattei et al., 2014. Bisphosphonates inhibit stellate cell activity and enhance antitumor effects of nanoparticle albumin bound-paclitaxel in pancreatic ductal adenocarcinoma. Mol. Cancer Therapeutics. 10.1158/1535-7163.MCT-14-0028.
    CrossRef  |  
  24. Erdogan, M.A. and B. Ozpolat, 2013. Abstract 514: Targeting of Voltage-gated sodium channel NaV1.5 inhibits cell proliferation and colony formation in breast and ovarian cancer cells. Cancer Res., Vol. 73. 10.1158/1538-7445.AM2013-514.
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