Dr. Mohd. Nazam Ansari
My Social Links

Dr. Mohd. Nazam Ansari

Professor
Department of Pharmacology and Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia

Highest Degree
Ph.D. in Pharmacology from Jamia Hamdard, New Delhi, India

Share this Profile

Biography

Dr. Mohd Nazam Ansari is currently working as Assistant Professor at Department of Pharmacology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, (Al-Kharj), Kingdom of Saudi Arabia. He has completed his Ph.D. in Pharmacology from Jamia Hamdard, New Delhi, India. During 2005 to 2007 he worked as Project Associate under Major Research Project Funded by University Grants Commission (UGC), Government of India. He is life member of Indian Pharmacological Society, India, and member of Indian Society for Technical Education, New Delhi, India. He is also serving as reviewer for Journal of Cardiovascular Pharmacology, Immunobiology, Toxicology Mechanisms and Methods, Pakistan Journal of Pharmaceutical Sciences, The Journal of the Renin-Angiotensin-Aldosterone System, Journal of Pharmacy Research and many others. Dr. Nazam received honors includes Travel Grant for Young Pharmacologists was awarded by Indian Pharmacological Society, recipient of University Grants Commission (UGC) Scholarship, and Registered Pharmacist-Delhi Pharmacy Council. He has completed 5 research projects as principal investigator and co-principal investigator. He has published 40 research articles in journals as well as 2 abstracts in scientific journals contributed as author/co-author. He also presented 8 abstract in scientific meeting. He also participated in number of workshop and training courses.

Area of Interest:

Pharmacology and Toxicology
100%
Diabetes
62%
Wound Healing
90%
Hepatotoxicity
75%
Anti-Inflammatory
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
103
Abstracts
7

Selected Publications

  1. Usmani, J., H. Kausar, S. Akbar, A. Sartaj and S.R. Mir, et al., 2023. Molecular docking of bacterial protein modulators and pharmacotherapeutics of Carica papaya leaves as a promising therapy for sepsis: synchronising in silico and in vitro studies. Molecules, Vol. 28. 10.3390/molecules28020574.
    CrossRef  |  Direct Link  |  
  2. Upadhyay, J., M.N. Ansari, A. Samad and A. Sayana, 2022. Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy. Exp. Biol. Med., 247: 779-787.
    CrossRef  |  Direct Link  |  
  3. Soliman, G.A., M.N. Ansari, M.H. Alqarni, A.I. Foudah, A. Alam, M.A. Salkini and H.S. Yusufoglu, 2022. Analgesic, antipyretic, anti-inflammatory, and hepatoprotective activities of Pulicaria crispa (Forssk.) Oliv. (Asteraceae). Braz. J. Pharm. Sci., Vol. 58. 10.1590/s2175-97902022e18851.
    CrossRef  |  Direct Link  |  
  4. Rehman, N.U., M.N. Ansari, A.H. Palla, A. Karim and F. Imam et al., 2022. Myrica salicifolia Hochst. ex A. Rich. suppress acetic acid-induced ulcerative colitis in rats by reducing TNF-alpha and interleukin-6, oxidative stress parameters and improving mucosal protection Hum. Exp. Toxicol., Vol. 41. 10.1177/09603271221102518.
    CrossRef  |  Direct Link  |  
  5. Najeeb Ur Rehman, M.N. Ansari, W. Ahmad and S.R. Ahamad, 2022. Dual inhibition of phosphodiesterase and Ca++ channels explains the medicinal use of Balanites aegyptiaca (L.) in hyperactive gut disorders. Plants, Vol. 11. 10.3390/plants11091183.
    CrossRef  |  Direct Link  |  
  6. Najeeb Ur Rehman, M.N. Ansari, W. Ahmad and M. Amir, 2022. The detailed pharmacodynamics of the gut relaxant effect and GC-MS analysis of the Grewia tenax fruit extract: In vivo and ex vivo approach. Molecules, Vol. 27. 10.3390/molecules27248880.
    CrossRef  |  Direct Link  |  
  7. Najeeb Ur Rehman, M.N. Ansari, W. Ahmad and M. Amir, 2022. GC–MS analysis and in vivo and ex vivo antidiarrheal and antispasmodic effects of the methanolic extract of Acacia nilotica. Molecules, Vol. 27. 10.3390/molecules27072107.
    CrossRef  |  Direct Link  |  
  8. Najeeb Ur Rehman, M.N. Ansari, A. Samad and W. Ahmad, 2022. In silico and ex vivo studies on the spasmolytic activities of fenchone using isolated guinea pig trachea. Molecules, Vol. 27. 10.3390/molecules27041360.
    CrossRef  |  Direct Link  |  
  9. Miglani, R., N. Parveen, A. Kumar, M.A. Ansari and S. Khanna et al., 2022. Degradation of xenobiotic pollutants: An environmentally sustainable approach. Metabolites, Vol. 12. 10.3390/metabo12090818.
    CrossRef  |  Direct Link  |  
  10. Kaur, T., J. Upadhyay, S. Pukale, A. Mathur and M.N. Ansari, 2022. Investigation of trends in the research on transferrin receptor-mediated drug delivery via a bibliometric and thematic analysis. Pharmaceutics, Vol. 14. 10.3390/pharmaceutics14122574.
    CrossRef  |  Direct Link  |  
  11. Anwer, M.K., E.A. Ali, M. Iqbal, M.M. Ahmed and M.F. Aldawsari et al., 2022. Development of sustained release baricitinib loaded lipid-polymer hybrid nanoparticles with improved oral bioavailability. Molecules, Vol. 27. 10.3390/molecules27010168.
    CrossRef  |  Direct Link  |  
  12. Ansari, M.N., G.A. Soliman, Najeeb Ur Rehman and M.K. Anwer, 2022. Crisaborole loaded nanoemulsion based chitosan gel: Formulation, physicochemical characterization and wound healing studies. Gels, Vol. 8. 10.3390/gels8050318.
    CrossRef  |  Direct Link  |  
  13. Althurwi, H.N., M.A.A. Salkini, G.A. Soliman, M.N. Ansari, E.O. Ibnouf and M.S. Abdel-Kader, 2022. Wound healing potential of Commiphora gileadensis stems essential oil and chloroform extract. Separations, Vol. 9. 10.3390/separations9090254.
    CrossRef  |  Direct Link  |  
  14. Upadhyay, J., J. Patra, N. Tiwari, N. Salankar, M.N. Ansari and W. Ahmad, 2021. Dysregulation of multiple signaling neurodevelopmental pathways during embryogenesis: a possible cause of autism spectrum disorder. Cells, Vol. 10. 10.3390/cells10040958.
    CrossRef  |  Direct Link  |  
  15. Upadhyay, G., N. Tiwari, H. Maurya, J. Upadhyay, R. Joshi and M.N. Ansari, 2021. In vivo wound-healing and antioxidant activity of aqueous extract of Roylea elegans leaves against physically induced burn model in wistar albino rats. 3 Biotech, Vol. 11. 10.1007/s13205-021-02993-4.
    CrossRef  |  Direct Link  |  
  16. Tiwari, N., J. Upadhyay, M.N. Ansari, S.S. Raza, W. Ahmad and M.A. Ansari, 2021. Experimental rodent models of vascular dementia: a systematic review. CNS Neurol. Disord. Drug Targets, Vol. 19. 10.2174/1871527319666210108123438.
    CrossRef  |  Direct Link  |  
  17. Singh, L., S. Roy, A. Kumar, S. Rastogi and D. Kumar et al., 2021. Repurposing combination therapy of voacamine with vincristine for downregulation of hypoxia-inducible factor-1α/fatty acid synthase co-axis and prolyl hydroxylase-2 activation in ER+ mammary neoplasia. Front. Cell Dev. Biol., Vol. 9. 10.3389/fcell.2021.736910.
    CrossRef  |  Direct Link  |  
  18. Singh, L., S. Bajaj, M. Gadewar, N. Verma and M.N. Ansari et al., 2021. Modulation of Host Immune Response Is an Alternative Strategy to Combat SARS-CoV-2 Pathogenesis. Front. Immunol., Vol. 12. 10.3389/fimmu.2021.660632.
    CrossRef  |  Direct Link  |  
  19. Singh, L., M. Singh, S. Rastogi, A. Choudhary and D. Kumar et al. 2021. Effect of Voacamine Upon Inhibition of Hypoxia Induced Fatty Acid Synthesis in a Rat Model of Methyln-Nitrosourea Induced Mammary Gland Carcinoma. BMC Mol. Cell Biol. 10.1186/s12860-021-00371-9.
    CrossRef  |  Direct Link  |  
  20. Rehman, N.U., M.N. Ansari, T. Haile, A. Karim, K.Y. Abujheisha, S.R. Ahamad and F. Imam, 2021. Possible tracheal relaxant and antimicrobial effects of the essential oil of Ethiopian thyme species (Thymus serrulatus hochst. ex benth.): a multiple mechanistic approach. Front. Pharmacol., Vol. 12. 10.3389/fphar.2021.615228.
    CrossRef  |  Direct Link  |  
  21. Mukerjee, S., A.S. Saeedan, M.N. Ansari and M. Singh 2021. Polyunsaturated Fatty Acids Mediated Regulation of Membrane Biochemistry and Tumor Cell Membrane Integrity. Membr. 10.3390/membranes11070479.
    CrossRef  |  Direct Link  |  
  22. Anwer, Md.K., M. Iqbal, M.M. Ahmed, M.F. Aldawsari and M.N. Ansari et al. 2021. Improving the Solubilization and Bioavailability of Arbidol Hydrochloride by the Preparation of Binary and Ternary β-Cyclodextrin Complexes with Poloxamer 188. Pharm. 10.3390/ph14050411.
    CrossRef  |  Direct Link  |  
  23. Ansari, M.N., N.U. Rehman, A. Karim, G.A. Soliman, M.A. Ganaie, M. Raish and A.M. Hamad, 2021. Role of oxidative stress and inflammatory cytokines (TNF-? and IL-6) in acetic acid-induced ulcerative colitis in rats: ameliorated by Otostegia fruticosa. Life, Vol. 11 10.3390/life11030195.
    CrossRef  |  Direct Link  |  
  24. Ansari, M.N., N.U. Rehman, A. Karim, F. Imam and A.M. Hamad, 2021. Protective effect of Thymus serrulatus essential oil on cadmium-induced nephrotoxicity in rats, through suppression of oxidative stress and downregulation of NF-?B, iNOS, and Smad2 mRN expression. Molecules, Vol. 26. 10.3390/molecules26051252.
    CrossRef  |  Direct Link  |  
  25. Ansari, M.N., A.S. Saeedan, S. Bajaj and L. Singh, 2021. Evaluation of antidiabetic and hypolipidemic activity of Barleria cristata linn. leaves in alloxan-induced diabetic rats. 3 Biotech, Vol. 11. 10.1007/s13205-021-02728-5.
    CrossRef  |  Direct Link  |  
  26. Alam, A., N.Ur Rehman, M.N. Ansari and A.H. Palla 2021. Effects of Essential Oils of Elettaria cardamomum Grown in India and Guatemala on Gram-Negative Bacteria and Gastrointestinal Disorders. Mol. 10.3390/molecules26092546.
    CrossRef  |  Direct Link  |  
  27. Ahmad, W., M.A. Khan, K. Ashraf, A. Ahmad and M.D. Ali et al., 2021. Pharmacological evaluation of safoof-e-pathar phori- a polyherbal unani formulation for urolithiasis. Front. Pharmacol., Vol. 12. 10.3389/fphar.2021.597990.
    CrossRef  |  Direct Link  |  
  28. Madkhali, H.A., M.A. Ganaie and M.N. Ansari, 2021. Red yeast rice mitigates high-fat diet induced-obesity related vascular dysfunction in wistar albino rats. Biointer. Res. Applied Chem., 11: 14290-14303.
    CrossRef  |  Direct Link  |  
  29. Yadav, R.K., M. Singh, S. Roy, S. Gautam and J.K. Rawat et al., 2020. Evaluation of α-linolenic acid-based intramammary nanosuspension for treatment of subclinical mastitis. J. Dairy Sci., 103: 2701-2706.
    CrossRef  |  Direct Link  |  
  30. Upadhyay, J., N. Tiwari and M.N. Ansari, 2020. Role of inflammatory markers in corona virus disease (COVID-19) patients: a review. Exp. Biol. Med., 245: 1368-1375.
    CrossRef  |  Direct Link  |  
  31. Upadhyay, J., N. Tiwari and M.N. Ansari, 2020. Cerebral palsy: aetiology, pathophysiology and therapeutic interventions. Clin. Exp. Pharmacol. Physiol., 47: 1891-1901.
    CrossRef  |  Direct Link  |  
  32. Upadhyay, J., M. Rana, N. Tiwari and M.N. Ansari, 2020. Teratogenic effect of chlorpyrifos and glyphosate on pregnant rats: biochemical and morphological evaluations. J. Pharm. Res. Int., 32: 133-145.
    CrossRef  |  Direct Link  |  
  33. Tiwari, N., J. Upadhyay, M.N. Ansari and R. Joshi, 2020. Novel ?-coronavirus (SARS-CoV-2): current and future aspects of pharmacological treatments. Saudi Pharm. J., 28: 1243-1252.
    CrossRef  |  Direct Link  |  
  34. Soliman, G.A., 2020. The potential cardioprotective effect of Matricaria chamomilla extract against diabetes-induced oxidative stress in rats. FARMACIA, 68: 269-279.
    CrossRef  |  Direct Link  |  
  35. Saeedan, A.S., M.A. Ganaie, B.L. Jan, H. Madhkali and M.N. Ansari et al., 2020. Brucine prevents DMH induced colon carcinogenesis in wistar rats. Int. J. Pharmacol., 16: 319-329.
    CrossRef  |  Direct Link  |  
  36. Saeedan, A., S. Rastogi and M. Ansari, 2020. Roflumilast counteracts dmh-induced preneoplastic colon damage in albino wistar rats. Hum. Exp. Toxicol., 39: 1545-1555.
    CrossRef  |  Direct Link  |  
  37. Rehman, N.U., M.N. Ansari and A. Samad, 2020. In silico, Ex vivo and in vivo studies of roflumilast as a potential antidiarrheal and antispasmodic agent: Inhibition of the PDE-4 enzyme and voltage-gated Ca++ ion channels. Molecules, Vol. 25. 10.3390/molecules25041008.
    CrossRef  |  Direct Link  |  
  38. Imam, F., N.U. Rehman, M.N. Ansari, W. Qamar, M. Afzal and K.S. Alharbi, 2020. Effect of roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca2+-channel. Saudi Pharm. J., 28: 698-702.
    CrossRef  |  Direct Link  |  
  39. Anwer, M.K., M.M. Ahmed, M.F. Aldawsari, S. Alshahrani and F. Fatima et al., 2020. Eluxadoline loaded solid lipid nanoparticles for improved colon targeting in rat model of ulcerative colitis. Pharmaceuticals, Vol. 13. 10.3390/ph13090255.
    CrossRef  |  Direct Link  |  
  40. Anwer, M.K., M.M. Ahmed, A. Alshetaili, B.K. Almutairy and A. Alalaiwe et al., 2020. Preparation of spray dried amorphous solid dispersion of diosmin in soluplus with improved hepato-renoprotective activity: in vitro anti-oxidant and In-vivo safety studies. J. Drug Delivery Sci. Technol., Vol. 60. 10.1016/j.jddst.2020.102101.
    CrossRef  |  Direct Link  |  
  41. Anwer, M.K., M. Mohammad, M. Iqbal, M.N. Ansari and E. Ezzeldin et al., 2020. Sustained release and enhanced oral bioavailability of rivaroxaban by PLGA nanoparticles with no food effect. J. Thrombosis Thrombolysis, 10.1007/s11239-019-02022-5.
    CrossRef  |  Direct Link  |  
  42. Ansari, M.N., N.U. Rehman, A. Karim, T. Bahta, K.Y. Abujheisha, S.R. Ahamad and F. Imam, 2020. Evaluation of bronchodialatory and antimicrobial activities of Otostegia fruticosa: A multi-mechanistic approach. Saudi Pharm. J., 28: 281-289.
    CrossRef  |  Direct Link  |  
  43. Ansari, M.N., 2020. Assessment of antidiarrheal, antispasmodic and antimicrobial activities of methanolic seeds extract of Peganum harmala L. (nitrariaceae). J. Pharm. Res. Int., 32: 74-82.
    CrossRef  |  Direct Link  |  
  44. Ansari, M.J., A. Alshetaili, I.A. Aldayel, F.M. Alablan and B. Alsulays et al., 2020. Formulation, characterization, in vitro and in vivo evaluations of self-nanoemulsifying drug delivery system of luteolin. J. Taibah Uni. Sci., 14: 1386-1401.
    CrossRef  |  Direct Link  |  
  45. Al-Omar, M.S., M. Naz, S.A.A. Mohammed, M. Mansha and M.N. Ansari et al., 2020. Pyrethroid-induced organ toxicity and anti-oxidant-supplemented amelioration of toxicity and organ damage: the protective roles of ascorbic acid and ?-tocopherol. Int. J. Environ. Res. Public Health, Vol. 17. 10.3390/ijerph17176177.
    CrossRef  |  Direct Link  |  
  46. Yadav, R.K., C.B. Tripathi, S.A. Saraf, M.N. Ansari and A.S. Saeedan et al., 2019. Alpha-linolenic acid based nano-suspension protect against lipopolysaccharides induced mastitis by inhibiting NFκBp65, HIF-1α and mitochondria-mediated apoptotic pathway in albino Wistar rats. Toxicol. Applied Pharmacol., Vol. 377. 10.1016/j.taap.2019.114628.
    CrossRef  |  Direct Link  |  
  47. Singh, M., S. Kasna, S. Roy, S. Aldosary, A.S. Saeedan, M.N. Ansari and G. Kaithwas, 2019. Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling. BMC Cancer, Vol. 19. 10.1186/s12885-019-6152-9.
    CrossRef  |  Direct Link  |  
  48. Naz, M., N. Rehman, M.N. Ansari, M. Kamal, M.A. Ganaie, A.S. Awaad and S.I. Alqasoumi, 2019. Comparative study of subchronic toxicities of mosquito repellents (coils, mats and liquids) on vital organs in Swiss albino mice. Saudi Pharm. J., 27: 348-353.
    CrossRef  |  Direct Link  |  
  49. Madkhali, H.A., K.M. Alharthy, M.A. Asiri, M.A. Ganaie, M.N. Ansari, N.U. Rehman and A.M. Hamad, 2019. Moringa oleifera Lam. (family Moringaceae) leaf extract attenuates high-fat diet-induced dyslipidemia and vascular endothelium dysfunction in Wistar albino rats. Trop. J. Pharm. Res., 18: 2597-2604.
  50. Kaithwas, G., J.K. Rawat, S. Roy, M. Singh and S. Gautam et al., 2019. Transcutaneous vagus nerve stimulation regulates the cholinergic anti-inflammatory pathway to counteract 1, 2-dimethyl hydrazine induced colon carcinogenesis in Albino wistar rats. Front. Pharmacol., Vol. 10. 10.3389/fphar.2019.00353.
    CrossRef  |  Direct Link  |  
  51. Devi, U., M. Singh, S. Roy, P.S. Gupta, M.N. Ansari, A.S. Saeedan and G. Kaithwas, 2019. Activation of prolyl hydroxylase‐2 for stabilization of mitochondrial stress along with simultaneous downregulation of HIF‐1α/FASN in ER+ breast cancer subtype. Cell Biochem. Funct., 37: 216-227.
    CrossRef  |  Direct Link  |  
  52. Devi, U., M. Singh, S. Roy, A.C. Tripathi and P.S. Gupta et al., 2019. PHD-2 activation: A novel strategy to control HIF-1α and mitochondrial stress to modulate mammary gland pathophysiology in ER+ subtype. Naunyn-Schmiedeberg's Arch. Pharmacol., 392: 1239-1256.
    CrossRef  |  Direct Link  |  
  53. Ansari, M.N., R.I. Aloliet, M.A. Ganaie, T.H. Khan, Najeeb-ur-Rehman, F. Imam and A.M. Hamad, 2019. Roflumilast, a phosphodiesterase 4 inhibitor, attenuates cadmium-induced renal toxicity via modulation of NF-κB activation and induction of NQO1 in rats. Hum. Exp. Toxicol., 38: 588-597.
    CrossRef  |  Direct Link  |  
  54. Ansari, M.N., M.A. Ganaie, N.U. Rehman, K.M. Alharthy and T.H. Khan et al., 2019. Protective role of Roflumilast against cadmium-induced cardiotoxicity through inhibition of oxidative stress and NF-κB signaling in rats. Saudi Pharm. J., 27: 673-681.
    CrossRef  |  Direct Link  |  
  55. Yusufoglu, H.S., M.N. Ansari, G.A. Soliman, A.I. Foudah, M.H. Alqarni, A. Alam and M.A. Salkini, 2018. Cardioprotective and nephroprotective actions of methanolic extract of Pulicaria somalensis herbs against carbon tetrachloride induced toxicity in rats. Indo Am. J. Pharm. Sci., 5: 2811-2823.
    Direct Link  |  
  56. Yusufoglu, H.S., G.A. Soliman, A.I. Foudah, M.S. Abdulkader, M.N. Ansari, A. Alam and M.A. Salkini, 2018. Protective role of aerial parts of Silene villosa alcoholic extract against CCl4-induced cardiac and renal toxicity in rats. Int. J. Pharmacol., 14: 1001-1009.
    CrossRef  |  Direct Link  |  
  57. Yadav, R.K., M. Singh, S. Roy, M.N. Ansari, A.S. Saeedan and G. Kaithwas, 2018. Modulation of oxidative stress response by flaxseed oil: Role of lipid peroxidation and underlying mechanisms. Prostaglandins Other Lipid Mediat., 135: 21-26.
    CrossRef  |  Direct Link  |  
  58. Yadav, R.K., J.K. Rawat, S. Gautam, M. Singh and M. Kumar et al., 2018. Antidiabetic activity of mefloquine via GLP-1 receptor modulation against STZ-NA-induced diabetes in albino wistar rats. 3 Biotech, Vol. 8. 10.1007/s13205-018-1250-y.
    CrossRef  |  Direct Link  |  
  59. Wani, T.A., A.H. Bakheit, M.N. Ansari, A.R.A. Al-Majed, B.M. Al-Qahtani and S. Zargar, 2018. Spectroscopic and molecular modeling studies of binding interaction between bovine serum albumin and roflumilast. Drug Des. Dev. Ther., 12: 2627-2634.
    CrossRef  |  Direct Link  |  
  60. Singh, L., S. Aldosary, A.S. Saeedan, M.N. Ansari and G. Kaithwas, 2018. Prolyl hydroxylase 2: A promising target to inhibit hypoxia-induced cellular metabolism in cancer cells. Drug Discov. Today, 23: 1873-1882.
    CrossRef  |  Direct Link  |  
  61. Saeedan, A.S., I. Singh, M.N. Ansari, M. Singh and J.K. Rawat et al., 2018. Effect of early natal supplementation of paracetamol on attenuation of exotoxin/endotoxin induced pyrexia and precipitation of autistic like features in albino rats. Inflammopharmacology, 26: 951-961.
    CrossRef  |  Direct Link  |  
  62. Roy, S., M. Singh, A. Rawat, U. Devi and S. Gautam et al., 2018. GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma. Int. J. Biochem. Cell Biol., 96: 51-62.
    CrossRef  |  Direct Link  |  
  63. Imam, F., N.O. Al-Harbi, M.M. Al-Harbi, M.A. Ansari and A.F. Al-Asmari et al., 2018. Apremilast prevent doxorubicin-induced apoptosis and inflammation in heart through inhibition of oxidative stress mediated activation of NF-κB signaling pathways. Pharmacol. Rep., 70: 993-1000.
    CrossRef  |  Direct Link  |  
  64. Gautam, S., S. Rani, S.A. Aldossary, A.S. Saeedan, M.N. Ansari and G. Kaithwas, 2018. Effects of phenidone (DuCLOX-2/5 inhibitor) against N-methyl-N-nitrosourea induced mammary gland carcinoma in albino rats. Toxicol. Applied Pharmacol., 351: 57-63.
    CrossRef  |  Direct Link  |  
  65. Gautam, S., A.K. Rawat, S.R. Sammi, S. Roy and M. Singh et al., 2018. DuCLOX-2/5 inhibition attenuates inflammatory response and induces mitochondrial apoptosis for mammary gland chemoprevention. Front. Pharmacol., Vol. 9. 10.3389/fphar.2018.00314.
    CrossRef  |  Direct Link  |  
  66. Ansari, M.N., M.A. Ganaie, T.H. Khan, A. Samad, H.A. Madkhali and S.R. Ahamad, 2018. Evaluation of the diuretic potentials of naringenin in hypercholesterolemic rats. Trop. J. Pharm. Res., 17: 239-244.
    Direct Link  |  
  67. Al-Saeedan, A.S., V. Gautam, M.N. Ansari, M. Singh and R.K. Yadav et al., 2018. Revisiting the systemic lipopolysaccharide mediated neuroinflammation: Appraising the effect of L-cysteine mediated hydrogen sulphide on it. Saudi Pharm. J., 26: 520-527.
    CrossRef  |  Direct Link  |  
  68. Yadav, S., V. Tiwari, M. Singh, R.K. Yadav and S. Roy et al., 2017. Comparative efficacy of alpha-linolenic acid and gamma-linolenic acid to attenuate valproic acid-induced autism-like features. J. Physiol. Biochem., 73: 187-198.
    CrossRef  |  Direct Link  |  
  69. Roy, S., A.K. Rawat, S.R. Sammi, U. Devi and M. Singh et al., 2017. Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention. Oncotarget, 8: 70049-70071.
    CrossRef  |  Direct Link  |  
  70. Gautam, S., S. Roy, M.N. Ansari, A.S. Saeedan, S.A. Saraf and G. Kaithwas, 2017. DuCLOX-2/5 inhibition: A promising target for cancer 3 chemoprevention. Breast Cancer, 24: 180-190.
    Direct Link  |  
  71. Ganaie, M.A., A. Samad, M.N. Ansari, T.H. Khan, P. Alam and S.R. Ahamad, 2017. Phytochemical screening and in-silico investigation of crocin and safranal, constituents of saffron for their cytochrome P450 2C9 enzyme activity. Int. J. Pharm. Res. Allied Sci., 6: 1-14.
  72. Tiwari, V., M. Singh, J.K. Rawat, U. Devi and R.K. Yadav et al., 2016. Redefining the role of peripheral LPS as a neuroinflammatory agent and evaluating the role of hydrogen sulphide through metformin intervention. Inflammopharmacology, 24: 253-264.
    CrossRef  |  Direct Link  |  
  73. Soliman, G.A., G.A. Gabr, F.I. Al-Saikhan, M.N. Ansari and T.H. Khan et al., 2016. Protective effects of two Astragalus species on ulcerative colitis in rats. Trop. J. Pharm. Res., 15: 2155-2163.
    CrossRef  |  Direct Link  |  
  74. Rani, A., S. Roy, M. Singh, U. Devi and R.K. Yadav et al., 2016. α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats. Inflammopharmacology, 24: 277-286.
    CrossRef  |  Direct Link  |  
  75. Mishra, R.K., S.R. Sammi, J.K. Rawat, S. Roy and M. Singh et al., 2016. Palonosetron attenuates 1, 2-dimethyl hydrazine induced preneoplastic colon damage through downregulating acetylcholinesterase expression and up-regulating synaptic acetylcholine concentration. RSC Adv., 6: 40527-40538.
    CrossRef  |  Direct Link  |  
  76. Manral, C., S. Roy, M. Singh, S. Gautam and R.K. Yadav et al., 2016. Effect of β-sitosterol against methyl nitrosourea-induced mammary gland carcinoma in albino rats. BMC Complement. Alternat. Med., Vol. 16. 10.1186/s12906-016-1243-5.
    CrossRef  |  Direct Link  |  
  77. Imam, F., N.O. Al-Harbi, M.M. Al-Harbi, M.A. Ansari and M.M. Almutairi et al., 2016. Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats. Toxicol. Mech. Methods, 26: 700-708.
    CrossRef  |  Direct Link  |  
  78. Devi, U., S. Dubey, V. Kumar, M. Singh and S. Gautum et al., 2016. Experimental models for autistic spectrum disorder-follow up for the validity. Rev. J. Autism Dev. Disorders, 3: 358-376.
    Direct Link  |  
  79. Anwer, M.K., M.A. Al-Mansoor, S. Jamil, R. Al-Shdefat, M.N. Ansari, F. Shakeel, 2016. Development and evaluation of PLGA polymer based nanoparticles of quercetin. Int. J. Biol. Macromol., 92: 213-219.
    CrossRef  |  Direct Link  |  
  80. Ansari, M.J., M.K. Anwer, S. Jamil, R. Al-Shdefata, B.E. Ali, M.M. Ahmad and M.N. Ansari, 2016. Enhanced oral bioavailability of insulin-loaded solid lipid nanoparticles: Pharmacokinetic bioavailability of insulin-loaded solid lipid nanoparticles in diabetic rats. Drug. Deliv., 23: 1972-1979.
    CrossRef  |  Direct Link  |  
  81. Al-Saikhan, F.I. and M.N. Ansari, 2016. Evaluation of the diuretic and urinary electrolyte effects of methanolic extract of Peganum harmala L. in Wistar albino rats. Saudi J. Biol. Sci., 23: 749-753.
    CrossRef  |  Direct Link  |  
  82. Abdulaziz, S.S., G.A. Gabr, G.A. Soliman, M.H. Fayed and M.N. Ansari, 2016. The potential anti-inflammatory and wound healing activities of Chitosan in rats. Adv. Biores., 7: 1-7.
    Direct Link  |  
  83. Ganaie, M.A., T.H. Khan, N.A. Siddiqui and M.N. Ansari, 2015. Ameliorative effect of methanol extract of Rumex vesicarius on CCl4-induced liver damage in Wistar albino rats. Pharm. Biol., 53: 1163-1167.
    CrossRef  |  PubMed  |  Direct Link  |  
  84. Gabr, G.A., G.A. Soliman, M.N. Ansari and N.M.M. Hassan, 2015. Ameliorative effect of Rumex pictus extract on paracetamol induced hepatotoxicity in rats. Adv. Biores., 6: 9-15.
    Direct Link  |  
  85. Donia, A.E.R.M., G.A. Soliman, F.I. Al-Saikhan, G.A. Gabr, M.A. Ganaie, M.N. Ansari and A.M. Radwan, 2015. The potential anti-inflammatory activity of essential oils of Pituranthos triradiatus and Anthemis deserti in rats. Bull. Environ. Pharmacol. Life Sci., 4: 28-31.
  86. Ansari, M.N., S.S. Al-Qahtani, M.A. Ganaie, T.H. Khan, F.I. Al-Saikhan, G.A. Gabr and G.A. Soliman, 2015. Evaluation of diuretic activity of methanolic extracts of mustard species in normal mice. Int. J. Biol. Pharm. Allied Sci., 4: 5722-5730.
    Direct Link  |  
  87. Ansari, M.N., 2015. Influence of dietary rocket leaveson diuresis and urinary electrolytes excretion in high fat diet-induced obese rats. Bull. Environ. Pharmacol. Life Sci., 4: 9-13.
  88. Ansari, M.J., M.K. Anwer, S. Jamil, R. Al-Shdefat, B.E. Ali, M.M. Ahmad and M.N. Ansari, 2015. Enhanced oral bioavailability of insulin-loaded solid lipid nanoparticles: pharmacokinetic bioavailability of insulin-loaded solid lipid nanoparticles in diabetic rats. Drug delivery, 10.3109/10717544.2015.1039666.
    CrossRef  |  Direct Link  |  
  89. Alafeefy, A.M., M.A. Bakht, M.A. Ganaie, M.N. Ansarie, N.N. El-Sayed and A.S. Awaad, 2015. Synthesis, analgesic, anti-inflammatory and anti-ulcerogenic activities of certain novel Schiff's bases as fenamate isosteres. Bioorg. Med. Chem. Lett., 25: 179-183.
    CrossRef  |  Direct Link  |  
  90. Khan, T.H., M.A. Ganaie, N.A. Siddiqui, A. Alam and M.N. Ansari, 2014. Antioxidant potential of Rumex vesicarius L.: In vitro approach. Asian Pac. J. Trop. Biomed., 4: 538-544.
    CrossRef  |  Direct Link  |  
  91. Ansari, M.N., M.A. Ganaie, T.H. Khan and G.A. Soliman, 2014. Protective role of Eruca sativa extract against testicular damage in streptozotocin-diabetic rats. Int. J. Biol. Pharm. Allied Sci., 3: 1067-1083.
    Direct Link  |  
  92. Ansari, M.N., 2014. Ameliorative effect of Eruca sativa extracts on glucose and urinary volume in streptozotocin-induced diabetic rats. Int. J. Biol. Pharm. Allied Sci., 3: 1092-1100.
  93. Ansari, M.N. and M.A. Ganaie, 2014. Ameliorative effect of rocket leaves on fertility in streptozotocin-induced diabetic rats. Int. Res. J. Biol. Sci., 3: 89-97.
    Direct Link  |  
  94. Khan, T.H., M. Ahmad, N.A. Siddiqui, A. Alam and M.N. Ansari, 2013. Anti-oxidant potential of Achyranthes aspera L.: In-vitro approach. World J. Pharm. Pharmaceut. Sci., 2: 6538-6547.
    Direct Link  |  
  95. Anwer, M.K., S. Jamil, M. Ahmad, M.N. Ansari and T.H. Khan, 2013. Inclusion complex of solid state aspirin with fulvic acid: dissolution, permeability, stability and preliminary pharmacological studies. J. Biol. Sci., 13: 302-312.
    CrossRef  |  Direct Link  |  
  96. Ahmad, M., M.N. Ansari, A. Alam and T.H. Khan, 2013. Oral dose of citrus peel extracts promotes wound repair in diabetic rats. Pak. J. Biol. Sci., 16: 1086-1094.
    CrossRef  |  Direct Link  |  
  97. Abdel Raheim, M.D., G.A. Soliman, M.H. Khataibeh, S.I. Alqasoumi and M.N. Ansari, 2013. Effect of Atriplexfarinosa, Atriplexnummularia and Ficusingenson ulcerative colitis in rats. Int. J. Biol. Pharm. Allied Sci., 2: 1247-1259.
  98. Bhandari, U., M.N. Ansari, V. Kumar, N. Khanna, F. Islam, C.D. Tripathi and G. Khanna, 2011. Attenuation of ischemia reperfusion-induced myocardial injuries by aqueous Embelia ribes Burm. extract in albino rats. Hamdard Medicus, 54: 33-41.
  99. Al-Dosari, M., S. Alqasoumi, M. Ahmad, M. Al-Yahya, M.N. Ansari and S. Rafatullah, 2011. Effect of Beta vulgaris L. on cholesterol rich diet-induced hypercholesterolemia in rats. Farmacia, 59: 669-678.
    Direct Link  |  
  100. Bhandari, U. and M.N. Ansari, 2009. Ameliorative effect of an ethanol extract of Embelia ribes fruits on isoproterenol-induced cardiotoxicity in diabetic rats. Pharm. Biol., 47: 669-674.
    CrossRef  |  Direct Link  |  
  101. Ansari, M.N., U. Bhandari, F. Islam and C.D. Tripathi, 2009. Effect of ethanol extract of Embelia ribes fruits on cardiac changes in rats subjected to ischemic reperfusion injury. Pharm. Biol., 47: 1180-1186.
    Direct Link  |  
  102. Ansari, M.N., G.K. Nigam and U. Bhandari, 2009. Effect of folic acid on hematological changes in methionine-induced hyperhomocysteinemia in rats. Indian J. Pharm. Sci., 71: 270-275.
    CrossRef  |  PubMed  |  Direct Link  |  
  103. Nigam, G.K., M.N. Ansari and U. Bhandari, 2008. Effect of rosuvastatin on methionine-induced hyperhomocysteinaemia and haematological changes in rats. Basic Clin. Pharmacol. Toxicol., 103: 287-292.
    CrossRef  |  PubMed  |  Direct Link  |  
  104. Kapoor, P., M.N. Ansari and U. Bhandari, 2008. Modulatory effect of curcumin on methionine-induced hyperlipidemia and hyperhomocysteinemia in albino rats. Indian J. Exp. Biol., 46: 534-540.
    PubMed  |  
  105. Bhandari, U., N. Jain, M.N. Ansari and K.K. Pillai, 2008. Beneficial effect of Embelia ribes ethanolic extract on blood pressure and glycosylated hemoglobin in streptozotocin-induced diabetes in rats. Fitoterapia, 79: 351-355.
    CrossRef  |  PubMed  |  Direct Link  |  
  106. Bhandari, U., M.N. Ansari, F. Islam and C.D. Tripathi, 2008. The effect of aqueous extract of Embelia ribes burm on serum homocysteine, lipids and oxidative enzymes in methionine induced hyperhomocysteinemia. Indian J. Pharmacol., 40: 152-157.
    CrossRef  |  Direct Link  |  
  107. Bhandari, U., M.N. Ansari and F. Islam, 2008. Cardioprotective effect of aqueous extract of Embelia ribes Burm fruits against isoproterenol-induced myocardial infarction in albino rats. Indian J. Exp. Biol., 46: 35-40.
    PubMed  |  Direct Link  |  
  108. Bhandari, U. and M.N. Ansari, 2008. Protective effect of aqueous extract of Embelia ribes burm fruits in middle cerebral artery occlusion-induced focal cerebral ischemia in rats. Indian J. Pharmacol., 40: 215-220.
    CrossRef  |  Direct Link  |  
  109. Bhandari, U. and M.N. Ansari, 2008. Potent antihyperglycaemic activity of the aqueous extract of Embelia ribes in streptozotocin-induced diabetic rats. Indian J. Exp. Biol., 46: 607-613.
    Direct Link  |  
  110. Bhandari, U. and M.N. Ansari, 2008. Effect of an ethanol extract of Embelia ribes fruits on isoproterenol-induced myocardial infarction in albino rats. Pharm. Biol., 46: 928-932.
  111. Ansari, M.N., U. Bhandari, F. Islam and C.D. Tripathi, 2008. Evaluation of antioxidant and neuroprotective effect of ethanolic extract of Embelia ribes Burm in focal cerebral ischemia/reperfusion-induced oxidative stress in rats. Fundam. Clin. Pharmacol., 22: 305-314.
    CrossRef  |  PubMed  |  Direct Link  |  
  112. Ansari, M.N. and U. Bhandari, 2008. Protective effect of Embelia ribes burm on methionine-induced hyperhomocysteinemia and oxidative stress in rat brain. Indian J. Exp. Biol., 46: 521-527.
  113. Ansari, M.N. and U. Bhandari, 2008. High performance thin layer chromatographic method for quantification of embelin from embelia ribes burm fruits. Indian Drugs, 45: 908-910.
  114. Ansari, M.N. and U. Bhandari, 2008. Cardioprotective activity of zingiber officinale roscoe in rats. Hamdard Medicus, 51: 26-29.
  115. Ansari, M.N. and U. Bhandari, 2008. Antihyperhomocysteinemic activity of an ethanol extract from Embelia ribes. in albino rats. Pharm. Biol., 46: 283-287.
    CrossRef  |  Direct Link  |  
  116. Ansari, M.N., U. Bhandari and K.K. Pillai, 2007. Protective role of curcumin in myocardial oxidative damage induced by isoproterenol in rats. Human Exp. Toxicol., 26: 933-938.
    CrossRef  |  Direct Link  |  
  117. Ansari, M.N., U. Bhandari and K.K. Pillai, 2006. Ethanolic zingiber officinale R. Extract pretreatment alleviates isoproternol-induced oxidative myocardial necrosis in rats. Indian J. Exp. Biol., 44: 892-897.
    PubMed  |