Dr. Rekha  Khandia

Dr. Rekha Khandia

Assistant Professor
Barkatullah University, India


Highest Degree
Ph.D. in Biotechnology from Barkatullah University, India

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Biography

Dr. Rekha Khandia is currently working as Assistant Professor (Genetics) in Department of Biochemistry and Genetics, Barkatullah University, Bhopal, India. The area of interest is development of molecular diagnostics and vaccine development through reverse genetics and also involved in finding biomolecules having angiogenesis modulation potential. She has completed her Ph.D. in Biotechnology from Barkatullaha University, Bhopal, Madhya Pradesh, India. She is having 11 years of research experience. She has 22 publications in journals contributed as author/co-author. Dr. Rekha is member of Society for Biosafety, and India and International society for infectious Diseases, USA. She is also serving as Principal Investigator in DST funded project under women Scientist scheme on project titled Development of reverse genetics backbone for type A Influenza virus at High Security Animal Disease Laboratory.

Area of Interest:

Animal and Veterinary Sciences
100%
Molecular Diagnostics
62%
Vaccine Development
90%
Reverse Genetics
75%
Biomolecules
55%

Selected Publications

  1. Kumar, U., R. Khandia, S. Singhal, N. Puranik and M. Tripathi et al., 2021. Insight into codon utilization pattern of tumor suppressor gene EPB41L3 from different mammalian species indicates dominant role of selection force. Cancers, Vol. 13. 10.3390/cancers13112739.
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  2. Klionsky, D.J., A.K. Abdel-Aziz, S. Abdelfatah, M. Abdellatif and A. Abdoli et al., 2021. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17: 1-382.
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  3. Khandia, R., T. Alqahtani and A.M. Alqahtani, 2021. Genes common in primary immunodeficiencies and cancer display overrepresentation of codon CTG and dominant role of selection pressure in shaping codon usage. Biomedicines, Vol. 9. 10.3390/biomedicines9081001.
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  4. Munjal, A. and R. Khandia, 2020. Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition. Adv. Protein Chem. Struct. Biol., 120: 85-122.
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  5. Khandia, R. and A. Munjal, 2020. Interplay between inflammation and cancer. Inflammatory Disord., Part A, 119: 199-245.
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  6. Khandia, R., S. Singhal, U. Kumar, A. Ansari and R. Tiwari et al., 2019. Analysis of nipah virus codon usage and adaptation to hosts. Front. Microbiol., Vol. 10. 10.3389/fmicb.2019.00886.
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  7. Khandia, R., M. Dadar, A. Munjal, K. Dhama and K. Karthik et al., 2019. A comprehensive review of autophagy and its various roles in infectious, non-infectious, and lifestyle diseases: current knowledge and prospects for disease prevention, novel drug design, and therapy. Cells, Vol. 8. 10.3390/cells8070674.
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  8. Dhama, K., S.K. Latheef, M. Dadar, H.A. Samad and A. Munjal et al., 2019. Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values. Front. Mol. Biosci., Vol. 6. 10.3389/fmolb.2019.00091.
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  9. Sood, R., N. Kumar, S. Bhatia, K.V. Chanu and C.L. Gupta et al., 2018. Neuraminidase inhibitors susceptibility profiles of highly pathogenic influenza a (H5N1) viruses isolated from avian species in India (2006–2015). Antiviral Res., 158: 143-146.
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  10. Singh, R.K., K. Dhama, R. Khandia, A. Munjal and K. Karthik et al., 2018. Prevention and control strategies to counter zika virus, a special focus on intervention approaches against vector mosquitoes—current updates. Front. Microbiol., Vol. 9. 10.3389/fmicb.2018.00087.
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  11. Singh, R.K., K. Dhama, K. Karthik, R. Tiwari and R. Khandia et al., 2018. Advances in diagnosis, surveillance and monitoring of Zika virus: An update. Front. Microbiol., Vol. 8. 10.3389/fmicb.2017.02677.
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  12. Singh, R.K., K. Dhama, K. Karthik, R. Khandia and A. Munjal et al., 2018. A comprehensive review on equine influenza virus: etiology, epidemiology, pathobiology, advances in developing diagnostics, vaccines, and control strategies. Front. Microbiol., 10.3389/fmicb.2018.01941.
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  13. Khandia, R., A. Munjal, K. Dhama, K. Karthik and R. Tiwari et al., 2018. Modulation of dengue/zika virus pathogenicity by antibody-dependent enhancement and strategies to protect against enhancement in zika virus infection. Front. Immunol., Vol. 9. 10.3389/fimmu.2018.00597.
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  14. Dhama, K., K. Karthik, R. Khandia, S. Chakraborty and A. Munjal et al., 2018. Advances in designing and developing vaccines, drugs and therapies to counter Ebola virus. Front. Immunol., Vol. 9. 10.3389/fimmu.2018.01803.
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  15. Yatoo, M.I., U. Dimri, A. Gopalakrishnan, K. Karthik and M. Gopi et al., 2017. Beneficial health applications and medicinal values of Pedicularis plants: A review. Biomed. Pharm., 95: 1301-1313.
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  16. Saeed, M., M. Naveed, M. Arif, M.U. Kakar and R. Manzoor et al., 2017. Green tea (Camellia sinensis) and l-theanine: Medicinal values and beneficial applications in humans. A comprehensive review. Biomed. Pharmacother., 95: 1260-1275.
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  17. Munjal, A., R. Khandia, K. Dhama, S. Sachan and K. Karthik et al., 2017. Advances in developing therapies to combat Zika virus: Current knowledge and future perspectives. Front. Microbiol., Vol. 8. 10.3389/fmicb.2017.01469.
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  18. Mishra, N., V.L. Tandonn, K. Dhama, R. Khandia and A. Munjal, 2016. Does Bougainvillea spectabilis protect swiss albino mice from aflatoxin-induced hepatotoxicity. Adv. Anim. Vet. Sci., 4: 250-257.
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  19. Mehra, R., A.N. Tikle, A. Saxena, A. Munjal, R. Khandia and M. Singh, 2016. Correlation-path-coefficient-and Genetic-diversity-in-blackgram-[viginamungo-l-hepper] correlation, path-coefficient and genetic diversity in blackgram [viginamungo (l) hepper]. Int. Res. J. Plant Sci., 7: 1-11.
  20. Jacob, A., R. Sood, K.V. Chanu, S. Bhatia and R. Khandia et al., 2016. Amantadine resistance among highly pathogenic avian influenza viruses (H5N1) isolated from India. Microb. Pathogenesis, 91: 35-40.
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  21. Bhatia, S., R. Khandia, R. Sood, S. Bhat and A. Siddiqui et al., 2016. Reverse genetics based rgH5N2 vaccine provides protection against high dose challenge of H5N1 avian influenza virus in chicken. Microb. Pathogenesis, 97: 172-177.
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  22. Premkrishnan, G.N., R. Sood, D. Hemadri, K.V. Chanu and R. Khandia et al., 2015. Cross-sectional study indicates nearly a quarter of sheep population in Karnataka state of India is infected with ovine herpesvirus 2. VirusDisease, 26: 180-188.
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  23. Khandia, R., A. Munjal, R.S. Bangrey, R. Mehra, K. Dhama and N.C. Sharma, 2015. Evaluation of silver nanoparticle mediated reduction of neovascularisation (angiogenesis) in chicken model. Adv. Anim. Vet. Sci., 3: 372-376.
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  24. Sood, R., R. Khandia, S. Bhatia, D. Hemadri and M. Kumar et al., 2014. Detection and molecular characterization of naturally transmitted sheep associated malignant catarrhal fever in cattle in India. Trop. Animal Health Prod., 46: 1037-1043.
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  25. Sengupta, D., A. Shaikh, S. Bhatia, A.K. Pateriya and R. Khandia et al., 2014. Development of single-chain Fv against the nucleoprotein of type A influenza virus and its use in Elisa. J. Virol. Methods, 208: 129-137.
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  26. Khandia, R., S. Bhatia, K.V. Chanu, R. Sood and K. Dhama, 2014. Anthrax toxin receptors, functions and their possible use in therapeutics: A review. Asian J. Anim. Vet. Adv., 9: 599-609.
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  27. Khandia, R., K. Rajukumar, A. Pateriya, S. Bhatia and H. Murugkar et al., 2014. In vitro evaluation of effect of B. anthracis lethal toxin on primary mammary tumor cells. Am. J. Infect. Dis., 10: 132-137.
  28. Khandia, R., B. Pattnaik, K. Rajukumar, A.K. Pateriya and H.V. Murugkar et al., 2013. Evaluation of a protective antigen gene based SYBR green I real time PCR for detection of Bacillus anthracis in field samples. Ind. J. Anim. Sci., 83: 118-123.
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  29. Bhatia, S., A. Kunal, R. Khandia, A. Siddiqui, A.K. Pateriya and R. Sood, 2013. Genetic and antigenic analysis of H5N1 viruses for selection of HA-donor virus for vaccine strains. Indian J. Virol., 24: 357-364.
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  30. Sood, R., M. Kumar, S. Bhatia, A.K. Pateriya and R. Khandia et al., 2012. Ovine herpesvirus type 2 infection in captive bison in India. Vet. Record, 170: 654-654.
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  31. Nagarajan, S., H.V. Murugkar, C. Tosh, P. Behera and R. Khandia et al., 2012. Comparison of a nucleoprotein gene based RT-PCR with real time RT-PCR for diagnosis of avian influenza in clinical specimens. Res. Vet. Sci., 93: 504-507.
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  32. Nagarajan, S., C. Tosh, D.K. Smith, J.S.M. Peiris and H.V. Murugkar et al., 2012. Avian influenza (H5N1) virus of clade 2.3. 2 in domestic poultry in India. Plos One, Vol. 7. 10.1371/journal.pone.0031844.
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  33. Dubey, S.C., N. Dahal, S. Nagarajan, C. Tosh and H.V. Murugkar et al., 2012. Isolation and characterization of influenza A virus (subtype H5N1) that caused the first highly pathogenic avian influenza outbreak in chicken in Bhutan. Vet. Microbiol., 155: 100-105.
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  34. Tosh, C., H.V. Murugkar, S. Nagarajan, S. Tripathi and M. Katare et al., 2011. Emergence of amantadine-resistant avian influenza H5N1 virus in India. Virus Genes, 42: 10-15.
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  35. Nagarajan, S., C. Tosh, H.V. Murugkar, G. Venkatesh and M. Katare et al., 2010. Isolation and molecular characterization of a H5N1 virus isolated from a Jungle crow (Corvus macrohynchos) in India. Virus Genes, 41: 30-36.
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  36. Nagarajan, S., H.V. Murugkar, C. Tosh, P. Behera and R. Jain et al., 2009. Avian influenza virus (H5N1) in chickens in India. Vet. Rec., 164: 128-128.
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  37. Murugkar, H.V., S. Nagarajan, C. Tosh, S. Bhatia and G. Venkatesh et al., 2008. H5N1 virus outbreaks in poultry in India. Vet. Rec., Vol. 162, .
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  38. Tosh, C., H.V. Murugkar, S. Nagarajan, S. Bhatia and A.K. Pateriya et al., 2007. Outbreak of avian influenza virus H5N1 in India. Vet. Rec., 161: 279-279.
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  39. Pattnaik, B., A.K. Pateriya, R. Khandia, C. Tosh and S. Nagarajan et al. 2006. Phylogenetic analysis revealed genetic similarity of the H5N1 avian influenza viruses isolated from HPAI outbreaks in chickens in Maharashtra, India with those isolated from swan in Italy and Iran in 2006. Current Sci., 91: 77-81.
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