Dr. Janendra Kumar Batra
My Social Links

Dr. Janendra Kumar Batra

Professor
Department of Biochemistry, Jamia Hamdard University, New Delhi, India

Highest Degree
Ph.D. in Medical Biochemistry from University of Delhi, Delhi, India

Share this Profile

Area of Interest:

Molecular Sciences
100%
Macromolecules
62%
Structural Dynamics
90%
Cellular Biochemistry
75%
Cell Biology
55%

Research Publications in Numbers

Books
0
Chapters
4
Articles
88
Abstracts
3

Selected Publications

  1. Attery, A. and J.K. Batra, 2017. Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities. Int. J. Biol. Macromol., 94: 445-450.
    Direct Link  |  
  2. Zaidi, S., M.A. Haque, S. Ubaid ullah, A. Prakash and M.I. Hassan, et al., 2016. Denatured states of yeast cytochrome c induced by heat and guanidinium chloride are structurally and thermodynamically different. J. Biomol. Struct. Dyn., 2016: 1-16.
    Direct Link  |  
  3. Singh, A., S. Ubaid ullah and J.K. Batra, 2016. Functional role of putative critical residues in mycobacterium tuberculosis RNase P protein. Int. J. Biochem. Cell Biol., 78: 141-148.
    Direct Link  |  
  4. Singh, A., S. Ubaid Ullah, A.K. Ramteke and J.K. Batra, 2016. Influence of conformation of M. Tuberculosis RNase P protein subunit on its function. PloS one, .
    Direct Link  |  
  5. Singh, A., A.K. Ramteke, T. Afroz and J.K. Batra, 2016. Insight into the role of histidine in RNR motif of protein component of RNase P of M. tuberculosis in catalysis. IUBMB Life, 68: 178-189.
    Direct Link  |  
  6. Choudhary, S., A. Pardo, R. Rosinke, J.K. Batra, S. Barth and R.S. Verma, 2016. Targeting c-kit receptor in neuroblastomas and colorectal cancers using stem cell factor (SCF)-based recombinant bacterial toxins. Appl. Microbiol. Biotechnol., 100: 263-277.
    Direct Link  |  
  7. Yadav, S.K. and J.K. Batra, 2015. Ribotoxin restrictocin manifests anti-HIV-1 activity through its specific ribonuclease activity. Int. J. Biol. Macromol., 76: 58-62.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Yadav, K.S. and J.K. Batra, 2015. Mechanism of anti-HIV activity of ribosome inactivating protein, saporin. Protein Pept. Lett., 22: 497-503.
    Direct Link  |  
  9. Parijat, P. and J.K. Batra, 2015. Role of DnaK in HspR-HAIR interaction of mycobacterium tuberculosis. IUBMB Life, 67: 816-827.
    Direct Link  |  
  10. Haque, M.A., S. Ubaid Ullah, S. Zaidi, M.I. Hassan, A. Islam, J.K. Batra and F. Ahmad, 2015. Characterization of pre-molten globule state of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25° C. Int. J. Biol. Macromol., 72: 1406-1418.
    Direct Link  |  
  11. Ubaid-ullah, S., M.A. Haque, S. Zaidi, M.I. Hassan and A. Islam, et al., 2014. Effect of sequential deletion of extra N-terminal residues on the structure and stability of yeast iso-1-cytochrome-c. J. Biomol. Struct. Dyn., 32: 2005-2016.
    Direct Link  |  
  12. Haque, M.A., S. Zaidi, U. Shah, A. Prakash, M.I. Hassan, A. Islam, J.K. Batra and F. Ahmad, 2014. In vitro and in silico studies of urea-induced denaturation of yeast iso-1- cytochrome c and its deletants at pH 6.0 and 25°C. J. Biomol. Struct. Dyn., 23: 1-10.
  13. Chopra, A. and J.K. Batra, 2014. Antimicrobial activity of human eosinophil granule proteins. In: Eosinophils: Methods and Protocols. Walsh, Garry, M. (Ed.)., Springer, Newyork, pp: 267-281.
  14. Sikriwal, D., D. Seth, S. Parveen, A. Malik, S. Broor and J.K. Batra, 2012. An insertion in loop L7 of human eosinophil-derived neurotoxin is crucial for its antiviral activity. J. Cell. Biochem., 113: 3104-3112.
    Direct Link  |  
  15. Rath, P., P.K. Singh and J.K. Batra, 2012. Functional and structural characterization of helicobacter pylori ClpX: a molecular chaperone of Hsp100 family. Protein Pept. Lett., 19: 1263-1271.
    Direct Link  |  
  16. Malik, A. and J.K. Batra, 2012. Antimicrobial activity of human eosinophil granule proteins: involvement in host defence against pathogens. Crit. Rev. Microbiol., 38: 168-181.
    Direct Link  |  
  17. Kaur, I., S.K. Yadav, G. Hariprasad, R.C. Gupta, A. Srinivasan, J.K. Batra and M. Puri, 2012. Balsamin, a novel ribosome-inactivating protein from the seeds of Balsam apple Momordica balsamina. Amino Acids, 43: 973-981.
    Direct Link  |  
  18. Bajaj, D. and J.K. Batra, 2012. The C-terminus of ClpC1 of Mycobacterium tuberculosis is crucial for its oligomerization and function. PloS one, .
    Direct Link  |  
  19. Bajaj, D. and J.K. Batra, 2012. Heat shock proteins in Mycobacterium tuberculosis: Involvement in survival and virulence of the pathogen. In: Understanding tuberculosis: Deciphering the secret life of the bacilli. Pere Joan C., (Ed.)., In Tech Open Science Open Minds, Croatia, pp: 257-276.
  20. Singh, A. and J.K. Batra, 2011. Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein. Biol. Chem., 392: 337-346.
    Direct Link  |  
  21. Rehman, M.T., P. Dey, M.I. Hassan, F. Ahmad and J.K. Batra, 2011. Functional role of glutamine 28 and arginine 39 in double stranded RNA cleavage by human pancreatic ribonuclease. PloS one, .
    Direct Link  |  
  22. Tapryal, S., L. Krishnan, J.K. Batra, K.J. Kaur and D.M. Salunke, 2010. Cloning, expression and efficient refolding of carbohydrate-peptide mimicry recognizing single chain antibody 2D10. Protein Expression Purif., 72: 162-168.
    Direct Link  |  
  23. Sikriwal, D. and J.K. Batra, 2010. Ribosome inactivating proteins and apoptosis. In: Toxic Plant Proteins, Plant Cell Monograph. Lord, J.M. and M.R. Hartley, (Ed.)., Springer-Verlag Berlin Heidelberg, New York, pp: 167-190.
  24. Sikriwal, D., D. Seth and J.K. Batra, 2009. Role of catalytic and non-catalytic subsite residues in ribonuclease activity of human eosinophil-derived neurotoxin. Biol. Chem., 390: 225-234.
    CrossRef  |  PubMed  |  Direct Link  |  
  25. Choudhary, R.K. and J.K. Batra, 2009. Engineering antibodies for cancer therapy. Curr. Sci., 96: 1592-1600.
  26. Sikriwal, D., P. Ghosh and J.K. Batra, 2008. Ribosome inactivating protein saporin induces apoptosis through mitochondrial cascade, independent of translation inhibition. Int. J. Biochem. Cell Biol., 40: 2880-2888.
    Direct Link  |  
  27. Kar, N.P., D. Sikriwal, P. Rath, R.K. Choudhary and J.K. Batra, 2008. Mycobacterium tuberculosis ClpC1 characterization and role of the N-terminal domain in its function. FEBS J., 275: 6149-6158.
  28. Sikriwal, D., D. Seth, P. Dey and J.K. Batra, 2007. Human eosinophil-derived neurotoxin: Involvement of a putative non-catalytic phosphate-binding subsite in its catalysis. Mol. Cell Biochem., 303: 175-181.
    CrossRef  |  PubMed  |  Direct Link  |  
  29. Dey, P., M. Tripathi and J.K. Batra, 2007. Involvement of loops L2 and L4 of ribonucleolytic toxin restrictocin in its functional activity. Protein Pept. Lett., 14: 125-129.
    Direct Link  |  
  30. Dey, P., A. Islam, F. Ahmad and J.K. Batra, 2007. Role of unique basic residues of human pancreatic ribonuclease in its catalysis and structural stability. Biochem. Biophys. Res. Commun., 360: 809-814.
    Direct Link  |  
  31. Ghosh, P. and J.K. Batra, 2006. The differential catalytic activity of ribosome-inactivating proteins saporin 5 and 6 is due to a single substitution at position 162. Biochem. J., 400: 99-104.
    Direct Link  |  
  32. Gaur, D. and J.K. Batra, 2005. Role of aspartic acid 121 in human pancreatic ribonuclease catalysis. Mol. Cell. Biochem., 275: 95-101.
    Direct Link  |  
  33. Basu, S.K., J.K.Batra and D.M. Salunke, 2004. Deep roots, open skies: new biology in India. Narosa Publishing House, New Delhi, India, Pages: 200.
  34. Batra, J.K., 2003. The aspergillus ribotoxins. Appl. Genomics Proteomics, 2: 145-159.
  35. Bagga, S., M.V. Hosur and J.K. Batra, 2003. Cytotoxicity of ribosome-inactivating protein saporin is not mediated through α2-macroglobulin receptor. FEBS Lett., 541: 16-20.
    Direct Link  |  
  36. Bagga, S., D. Seth and J.K. Batra, 2003. The cytotoxic activity of ribosome-inactivating protein Saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities. J. Biol. Chem., 278: 4813-4820.
    CrossRef  |  PubMed  |  Direct Link  |  
  37. Goyal, A., D. Seth and J.K. Batra, 2002. Role of cis prolines 112 and 126 in the functional activity of ribonucleolytic toxin restrictocin. Biochem. Biophys. Res. Commun., 295: 812-817.
    Direct Link  |  
  38. Gaur, D., D. Seth and J.K. Batra, 2002. Glycine 38 is crucial for the ribonucleolytic activity of human pancreatic ribonuclease on double-stranded RNA. Biochem. Biophy. Res. Commun., 297: 390-395.
    CrossRef  |  PubMed  |  Direct Link  |  
  39. Nayak, S.K., S. Bagga, D. Gaur, D.T. Nair, D.M. Salunke and J.K. Batra, 2001. Mechanism of specific target recognition and RNA hydrolysis by ribonucleolytic toxin restrictocin. Biochem., 40: 9115-9124.
    Direct Link  |  
  40. Gaur, D., S. Swaminathan and J.K. Batra, 2001. Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor Generation of inhibitor-resistant cytotoxic variants. J. Biol. Chem., 276: 24978-24984.
    Direct Link  |  
  41. Nayak, S.K. and J.K. Batra, 2000. Localization of the catalytic activity in restrictocin molecule by deletion mutagenesis. Eur. J. Biochem., 267: 1777-1783.
    Direct Link  |  
  42. Goyal, A. and J.K. Batra, 2000. Inclusion of a furin-sensitive spacer enhances the cytotoxicity of ribotoxin restrictocin containing recombinant single-chain immunotoxins. Biochem. J., 345: 247-254.
    Direct Link  |