Dr. Arumugam  Sudha

Dr. Arumugam Sudha

Teaching Assistant
Alagappa University, India


Highest Degree
Ph.D. in Bioinformatics from Alagappa University, India

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Area of Interest:

Molecular Sciences
100%
Molecular Modeling
62%
Spectroscopy
90%
Cancer Biology
75%
Phytochemistry
55%

Selected Publications

  1. Sudha, A., P. Srinivasan, V. Kanimozhi, K. Palanivel and B. Kadalmani, 2018. Antiproliferative and apoptosis-induction studies of 5-hydroxy 3′,4′,7-trimethoxyflavone in human breast cancer cells MCF-7: An in vitro and in silico approach. J. Receptors Signal Transduction, 38: 179-190.
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  2. Alharbi, N.S., M. Govindarajan, S. Kadaikunnan, J.M. Khaled and T.N. Almanaa et al., 2018. Nanosilver crystals capped with Bauhinia acuminate phytochemicals as new antimicrobials and mosquito larvicides. J. Trace Elem. Med. Biol., 50: 146-153.
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  3. Sudha, A., J. Jeyakanthan and P. Srinivasan, 2017. Green synthesis of silver nanoparticles using Lippia nodiflora aerial extract and evaluation of their antioxidant, antibacterial and cytotoxic effects. Resour. Efficient Technol., 3: 506-515.
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  4. Thamilarasan, V., N. Sengottuvelan, A. Sudha, P. Srinivasan and G. Chakkaravarthi, 2016. Cobalt (III) complexes as potential anticancer agents: Physicochemical, structural, cytotoxic activity and DNA/Protein interactions. J. Photochem. Photobiol. Biol., 162: 558-569.
    CrossRef  |  Direct Link  |  

  5. Sudha, A., P. Srinivasan, V. Thamilarasan and N. Sengottuvelan, 2016. Exploring the binding mechanism of 5-hydroxy- 3`,4`,7- trimethoxyflavone with bovine serum albumin: Spectroscopic and computational approach. Spectrochim. Acta Part Mol. Biomol. Spectrosc., 157: 170-181.
    CrossRef  |  Direct Link  |  

  6. Sudha, A., J. Jeyakanthan and P. Srinivasan, 2016. Protective effect of 5-hydroxy-3′,4′,7-trimethoxyflavone against inflammation induced by lipopolysaccharide in RAW 264.7 macrophage: in vitro study and in silico validation. Med. Chem. Res., 25: 1754-1767.
    CrossRef  |  Direct Link  |  

  7. Gopinath, K., M. Chinnadurai, N.P. Devi, K. Bhakyaraj and S. Kumaraguru et al., 2016. One-pot synthesis of dysprosium oxide nano-sheets: Antimicrobial potential and cyotoxicity on A549 lung cancer cells. J. Cluster Sci., 28: 621-635.
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  8. Bhakyaraj, K., S. Kumaraguru, K. Gopinath, V. Sabitha and P.R. Kaleeswarran et al., 2016. Eco-Friendly synthesis of palladium nanoparticles using Melia azedarach leaf extract and their evaluation for antimicrobial and larvicidal activities. J. Cluster Sci., 10.1007/s10876-016-1114-8.
    CrossRef  |  Direct Link  |  

  9. Bhakyaraj, K., S. Kumaraguru, K. Gopinath, V. Sabitha and P.R. Kaleeswarran et al., 2016. Eco-friendly synthesis of palladium nanoparticles using Melia azedarach leaf extract and their evaluation for antimicrobial and larvicidal activities. J. Cluster Sci., 28: 463-476.

  10. Thamilarasan, V., N. Sengottuvelan, A. Sudha, P. Srinivasan and A. Siva, 2015. Synthesis, molecular structure, theoretical calculation, DNA/protein interaction and cytotoxic activity of manganese (III) complex with 8-hydroxyquinoline. J. Photochem. Photobiol. Biol., 142: 220-231.
    CrossRef  |  Direct Link  |  

  11. Sudha, A. and P. Srinivasan, 2015. In vitro, Fluorescence quenching and Computational studies on the interaction between lipoxygenase and 5-hydroxy- 3`,4`,7- trimethoxyflavone from Lippia nodiflora L. J. Recept. Signal Transduction, 35: 569-577.
    CrossRef  |  Direct Link  |  

  12. Sudha, A., P. Srinivasan anjd P. Rameshthangam, 2014. Exploration of potential EGFR inhibitors: a combination of Pharmacophore-based virtual screening, atom-based 3D-QSAR and molecular docking analysis. J. Recept. Signal Transduction, 35: 137-148.
    CrossRef  |  Direct Link  |  

  13. Sudha, A. and P. Srinivasan, 2014. Bioassay-guided isolation, identification and molecular ligand-target insight of lipoxygenase inhibitors from leaves of Anisomeles malabarica R.Br. Pharmacogn. Mag., 10: 596-605.
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  14. Sudha, A. and P. Srinivasan, 2014. Bioassay-guided isolation and antioxidant evaluation of flavonoid compound from aerial parts of Lippia nodiflora L. Biomed. Res. Int., 10.1155/2014/549836.
    CrossRef  |  Direct Link  |  

  15. Srinivasan, P., P. Chellaperumal and A. Sudha, 2014. Discovery of novel inhibitors for Nek6 protein through homology model assisted structure based virtual screening and molecular docking approaches. Sci. World J., 10.1155/2014/967873.
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  16. Suryanarayanan, V., A. Sudha, S. Rajamanikandan, R. Vanajothi and P. Srinivasan, 2013. Atom-based 3D QSAR studies on novel N-B-D-Xylosylindole derivatives as SGLT2 inhibitors. Med. Chem. Res., 22: 615-624.
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  17. Sudha, A., K. Sumathi, S. Manikandaselvi, N.M. Prabhu and P. Srinivasan, 2013. Anti-hepatotoxic activity of crude flavanoid fraction of Lippia nodiflora L. on ethanol induced liver injury in rats. Asian J. Anim. Sci., 7: 1-13.

  18. Sudha, A. and P. Srinivasan, 2013. Physicochemical and Phytochemical profiles of aerial parts of Lippia nodiflora L. Int. J. Pharma. Sci. Res., 4: 4263-4271.
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  19. Vanajothi, R., S. Rajamanikandan, A. Sudha and P. Srinivasan, 2012. Structural and functional analysis of KIT gene encoding receptor tyrosine kinase and its interaction with sunitinib and HDAC inhibitors: An in silico approach. Pakistan J. Biol. Sci., 15: 121-131.
    PubMed  |  

  20. Vanajothi, R., A. Sudha, R. Manikandan, P. Rameshthangam and P. Srinivasan, 2012. Luffa acutangula and Lippia nodiflora leaf extract induces growth inhibitory effect through induction of apoptosis on human lung cancer cell line. Biomed. Preventive Nutr., 2: 287-293.
    CrossRef  |  

  21. Sudha, A., P. Srinivasan, N.S. Manikandaselvi and R. Thinagarbabu, 2012. Protective effect and antioxidant role of Achyranthus aspera L. against ethanol-induced oxidative stress in rats. Inter. J. Pharm. Pharm. Sci., 4: 280-284.

  22. Srinivasan, P., A. Sudha, N. Umamaheswari, R. Vanajothi and P. Rameshthangam, 2012. Modeling of quorum sensing regulatory protein of Vibrio harveyi from shrimp aquaculture system and in silico prediction of active drugs. Inter. J. Curr. Sci., 2: 5-13.

  23. Rajamanikandan, S., R. Vanajothi, A. Sudha, P. Rameshthangam and P. Srinivasan, 2012. In silico analysis of deleterious SNPs of the FGFR2 gene. J. Biol. Sci., 12: 83-90.

  24. Srinivasan, P., A. Sudha, R. Manikandan and C. Arulvasu, 2011. Molecular docking studies of 1, 2 disubstituted Idopyranose from Vitex negundo with anti-diabetic activity of type 2 diabetes. Int. J. Pharma. Bio. Sci., 2: 68-83.
    Direct Link  |  

  25. Srinivasan, P., A. Sudha, A.S. Hameed, S.P. Kumar and M. Karthikeyan, 2011. Screening of medicinal plants for inhibitors of NS5B polymerase of hepatitis C virus (HCV) using molecular docking studies. J. Pharm. Res., 4: 136-140.

  26. Sudha, A., P. Srinivasan, N. Rameshkannan and R. Vanajothi, 2010. Protective effects of Achras zapota Linn. seed extract in carbon tetrachloride induced hepatotoxicity in rats. Inventi. Impact Ethnopharmacol., 1: 1-3.
    Direct Link  |  

  27. Srinivasan, P., A. Sudha, P. Bharathajothi, K. Rajaguru, P. Rameshthangam, R. Manikandan and C. Arulvasu, 2010. Effects of anti-inflammatory and antipyretic activity of Anisomeles malabarica R.Br. J. Pharm. Res., 3: 1598-1601.
    Direct Link  |