Dr. Haseeb  Zubair
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Dr. Haseeb Zubair

Post-doctoral Fellow
USA Mitchell Cancer Institute, USA


Highest Degree
Ph.D. in Biochemistry from Aligarh Muslim University, Aligarh, India

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Area of Interest:

Molecular Sciences
100%
Biochemistry
62%
Molecular Microbiology
90%
Bioinformatics
75%
Cancer
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zubair, H., S. Azim, S.K. Srivastava, A. Bhardwaj and S. Marimuthu et al., 2016. Cancer Stem Cells: Concept, Significance and Management. In: Stem Cells in Toxicology and Medicine. Sahu, S.C. (Ed.). John Wiley and Sons Ltd., Chichester, UK., ISBN: 9781119135418, pp: 375-413..
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  2. Zubair, H., S. Azim, S.K. Srivastava, A. Ahmad, A. Bhardwaj, M.A. Khan, G.K. Patel, S. Arora, J.E. Carter, S. Singh, A.P. Singh, 2016. Glucose metabolism reprogrammed by overexpression of IKK-epsilon promotes pancreatic tumor growth. Cancer Res., .
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  3. Zubair, H., S. Azim, H.Y. Khan, M.F. Ullah, A.P. Singh, S.M. Hadi, A. Ahmad, 2016. Mobilization of intracellular copper by gossypol and apogossypolone leads to reactive oxygen species-mediated cell death: putative anticancer mechanism. Int J. Mol. Sci., 17: 973-973.
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  4. Ullah, M.F., A. Ahmad, S.H. Bhat, H.Y. Khan, H. Zubair, S.M. Hadi, 2016. Simulating hypoxia-induced acidic environment in cancer cells facilitates mobilization and redox-cycling of genomic copper by daidzein leading to pro-oxidant cell death: implications for the sensitization of resistant hypoxic cancer cells to therapeutic challenges. Biometals 29: 299-310.
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  5. Patton M.C., H. Zubair, G.K. Patel, S. Singh, A.P. Singh, 2016. Exosomes from hypoxic pancreatic cancer cells confer resistance to subsequent hypoxia insult. Cancer Res., 76: 2799-2799.
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  6. Azim, S., H. Zubair, S.K. Srivastava, A. Bhardwaj, A. Ahmad, A. Zubair, S. Singh, M. Khushman, A.P. Singh, 2016. Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer. Sci. Rep., 29: 28446-28446.
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  7. Rehman, S.U., H. Zubair, T. Sarwar, M.A. Husain, H.M. Ishqi, S. Nehar, M. Tabish, 2015. Redox cycling of Cu(II) by 6-mercaptopurine leads to ROS generation and DNA breakage: possible mechanism of anticancer activity. Tumor Biol., 36: 1237-1244.
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  8. Khan, M.A., S.K. Srivastava, A. Bhardwaj, S. Singh, S. Arora, , H. Zubair, J.E. Carter, A.P. Singh, 2015. Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications. Oncotarget 6: 39140-39150.
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  9. Khan, M.A., H. Zubair, S.K. Srivastava, S. Singh and A.P. Singh, 2015. Insights into the Role of microRNAs in Pancreatic Cancer Pathogenesis: Potential for Diagnosis, Prognosis and Therapy. In: microRNA: Cancer. Santulli, G. (Ed.). Springer International Publishing, Switzerland., ISBN: 978-3-319-23729-9, pp: 71-87..
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  10. Zaidi, Y., F. Arjmand, N. Zaidi, J.A. Usmani, H. Zubair, K. Akhtar, M. Hossain, G.G.H.A. Shadab, 2014. A comprehensive biological insight of trinuclear copper(ii)-tin(iv) chemotherapeutic anticancer drug entity: in vitro cytotoxicity and in vivo systemic toxicity studies. Metallomics, 6: 1469-1479.
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  11. Khan, H.Y., H. Zubair, M. Faisal, M.F. Ullah, M. Farhan, F.H. Sarkar, A. Ahmad , S.M. Hadi, 2014. Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action. Mol. Nutr. Food Res., 58: 437-446.
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  12. Zubair, H., H.Y. Khan, A. Sohail, S. Azim, M.F. Ullah, A. Ahmad, F.H. Sarkar, S.M. Hadi, 2013. Redox cycling of endogenous copper by thymoquinone leads to ROS mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants. Cell Death Dis., 6: e660-e660.
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  13. Ahmad, M.K., H. Zubair, R. Mahmood, 2013. DNA damage and DNA-protein cross linking induced in rat intestine by the water disinfection by product potassium bromate. Chemosphere 91: 1221-1224.
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  14. Zubair, H., M.F. Ullah, A. Ahmad, H.Y. Khan and S.M. Hadi, 2012. Soy Isoflavone Genistein in Cancer Chemoprevention: Role of Endogenous Copper and Involvement of Reactive Oxygen Species. In: Soy: Nutrition, Consumption and Health. Ahmad, A. (Ed.). Nova Science, New York, USA., ISBN: 978-1-62081-847-3, pp: 333-344..
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  15. Zubair, H., H.Y. Khan, M.F. Ullah, A. Ahmad, Wu. Daocheng, S.M. Hadi, 2012. Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage. Eur. J. Pharm. Sci., 47: 280-286.
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  16. Khan, H.Y., H. Zubair, M.F. Ullah, A. Ahmad, S.M. Hadi, 2012. A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols. Cur. Drug Targets, 13: 1738-1749.
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  17. Zubair, H., H.Y. Khan, M.F. Ullah, S.M. Hadi, 2011. A prooxidant based anticancer mechanism of plant derived polyphenolic nutraceuticals. The FASEB J., 25: 979.1-979.1.
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  18. Ullah, M.F., H.Y. Khan, H. Zubair, U. Shamim, S.M. Hadi, 2011. The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer. Cancer Chem. Pharm., 67: 103-110.
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  19. Ullah, M.F., A. Ahmad, H.Y. Khan, H. Zubair, F.H. Sarkar, S.M. Hadi, 2011. The prooxidant action of dietary antioxidants leading to cellular DNA breakage and anticancer effects: implications for chemotherapeutic action against cancer Cell Biochem. Biophys., 67: 103-110.
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  20. Ullah, M.F., A. Ahmad, H. Zubair, H.Y. Khan, Z. Wang, F.H. Sarkar, S.M. Hadi, 2011. Soy isoflavone genistein induces cell death in breast cancer cells through mobilization of endogenous copper ions and generation of reactive oxygen species Mol. Nutr. Food Res., 55: 553-559.
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  21. Khan, H.Y., H. Zubair, M.F. Ullah, A. Ahmad, S.M. Hadi, 2011. Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism. biometals 24: 1169-1178.
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  22. Khan, M.W., A. Naqshbandi, H. Zubair, H. Ahsan, S.A Khan and F.H. Khan, 2010. Nitrite, a reactive nitrogen species, protects human alpha-2-macroglobulin from halogenated oxidant, HOCl. Protein J., 29: 276-282.
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  23. Khan, H.Y., H. Zubair, M.F. Ullah and S.M. Hadi, 2010. A prooxidant mechanism of dietary polyphenols in cancer chemoprevention. Polyphenols Commun., 1: 28-29.
  24. Hadi, S.M., M.F. Ullah, A.S. Azmi, A. Ahmad, U. Shamim, H. Zubair and H.Y. Khan, 2010. Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer. Pharmaceutical Res., 27: 979-988.
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  25. Ullah, M.F., H. Zubair, H.Y. Khan and S.M. Hadi, 2009. Soy Isoflavone Genistein in Cancer Chemoprevention. In: Isoflavones Biosynthesis, Occurrence and Health Effects. Thompson, M.J. (Ed.). Nova Science, New York, USA., ISBN: 978-1-61728-113-6, pp: 271-284..
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