Dr. Seema  Rai
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Dr. Seema Rai

Associate Professor
Guru Ghasidas Vishwavidyalaya, India

Highest Degree
Ph.D. in Zoology from Banaras Hindu University, India

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Dr. seema Rai is working as Associate professor in Department of Zoology, Guru Ghasidas Central University, Bilaspur Chhattisgarh. She has published more than 30 Research papers in journals of repute. She is a member of various Associations and socities like • Society for reproductive Biology and Endocrinology (SRBCE Life Member
• Indian Pineal Group Studies (IPSH) Life Member
• Indian Society for Reproduction and Fertility (ISSRF) Life Member
• Asia Oceania Society on Photobiology, Japan. She is a member of various expert committies of the Universities.

Area of Interest:

Animal and Veterinary Sciences
Reproductive Physiology
Fish Biology

Research Publications in Numbers


Selected Publications

  1. Singroul, S., Y.A. Hajam, H. Ghosh, S. Rai and M. Basheer, 2018. Nephroprotective effect of exogenous melatonin and plant extract of Costus igneous Nak. Res. Rev.: J. Drug Formulation Dev. Prod., 5: 16-24.
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  2. Purohit, A., S. Rai, Y.A. Hajam, H. Ghosh and M. Basheer, 2018. Hepatoprotective role of exogenous melatonin and insulin plant (Costus igneous Nak.) extract against the streptozotocin induced diabetes in rats. Res. Rev.: J. Drug Design Discovery, 5: 25-36.
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  3. Hajam, Y.A., S. Rai, S. Shree, M. Basheer and H. Ghosh, 2018. Retrieval of reproductive complications by exogenous melatonin treatment in streptozotocin induced diabetic rat model. Res. Rev. J. Zool. Sci., 5: 96-104.
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  4. Hajam, Y.A., S. Rai, M. Basheer, H. Ghosh and S. Singh, 2018. Protective role of melatonin in streptozotocin induced pancreatic damages in diabetic wistar rat. Pak. J. Biol. Sci., 21: 423-431.
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  5. Hajam, Y.A., S. Rai, H. Ghosh, M. Basheer and N. Dewangan, 2018. Reversal in thyroid gland impairments by exogenous melatonin in streptozotocin induced diabetic male rat. Int. J. Theor. Applied Sci., 10: 61-67.
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  6. Gupta, D., S. Rai, Y.A. Hajam, H. Ghosh and M. Basheer, 2018. Neuroprotective role of exogenous melatonin and insulin plant (Costus igneus Nak.) extract on brain in streptozotocin-induced diabetes in female rat. Res. Rev. J. Pharm., 5: 33-41.
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  7. Ghosh, H., S. Rai, Y.A. Hajam and M. Basheer, 2018. Existence of reciprocal expression of melatonin receptor MT1, MT2 on thyroid and ovary modulates metabolic and reproductive physiology via ERα, Dio2 and TRα receptor cross talk during PCO rats. Int. J. Theor. Applied Sci., 10: 253-263.
  8. Ghosh, H., S. Rai, M. Basheer and Y.A. Hajam, 2018. Receptor cross talk and interplay between melatonin and ovarian thyroid axis in a letrozole induced polycystic (Pco) rat. J. Clin. Cell. Immunol., Vol. 9. 10.4172/2155-9899.1000552.
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  9. Basheer, M., S. Rai, H. Ghosh and Y.A. Hajam, 2018. Therapeutic efficacy of melatonin against polycystic ovary syndrome (PCOS) induced by letrozole in Wistar rat. Pak. J. Biol. Sci., 21: 340-347.
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  10. Basheer, M., S. Rai, H. Ghosh and Y.A. Hajam, 2018. Protective role of seed extract of Tephrosia purpurea in letrozole induced polycystic ovary syndrome in wistar rats. J. Biol. Sci., 18: 458-467.
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  11. Basheer, M., S. Rai, H. Ghosh and Y.A. Hajam, 2018. Phytochemical estimation of Tephrosia purpurea seed extract. Int. J. Theor. Applied Sci., 10: 51-53.
  12. Hajam, Y.A., S. Rai, A. Roy, M. Basheer and H. Ghosh, 2017. Repossession of brain complications in a streptozotocin induced diabetic rat by exogenous melatonin administration. Int. J. Zool. Res., 13: 64-73.
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  13. Rai, S., Y.A. Hajam, M. Basheer and H. Ghosh, 2016. Biochemical and histopathological inflections in hepato-renal tissues of streptozotocin (STZ) induced diabetic male rats: Impact of exogenous melatonin administration. J. Clin. Res. Bioeth., Vol. 7. 10.4172/2155-9627.1000290.
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  14. Rai, S., H. Ghosh and M. Basheer, 2016. Phytochemical characterization and antioxidative property of ocimum canum: Effect of ethanolic extract of leaves and seeds on basic immunologic and metabolic status of male rats. J. Immunobiol., 10.4172/jib.1000108.
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  15. Basheer, M and S. Rai, 2016. Melatonin vs. phytomelatonin: Therapeutic uses with special reference to polycystic ovarian syndrome (PCOS). Cogent Biol., 10.1080/23312025.2015.1136257.
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  16. Rai, S., M. Basheer, H. Ghosh, D. Acharya and Y.A. Hajam, 2015. Melatonin attenuates free radical load and reverses histologic architect and hormone profile alteration in female rat: An in vivo study of pathogenesis of letrozole induced poly cystic ovary. J. Clin. Cell. Immunol., Vol. 6. 10.4172/2155-9899.1000384.
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  17. Rai, S., M. Basheer, D. Acharya, H. Ghosh and P. Bhattacharya, 2015. Impairment of ovarian and uterine cellular architecture, total protein content: A consequence of lead nitrate induced increased free radical load. Adv. Bisci. Bioeng., 3: 49-55.
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  18. Rai, S., C. Haldar, D. Acharaya and M. Basheer, 2015. Biological significance of reproductive phase-dependent adjustment of metabolic, energetic and immunologic adaptations in a male seasonal tropical breeder F. Pennanti: role of melatonin and thyroxin. Int. J. Multidiscipl. Appr. Stud., 2: 148-164.
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  19. Turkowska, E., S. Rai, P. Majewski and K. Skwarlo-Sonta, 2013. Pineal oscillator functioning in the chicken - Effect of photoperiod and melatonin. Chronobiol. Int., 31: 134-143.
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  20. Turkowska, E., S. Rai, P. Majewski and K. Skwarlo-Sonta, 2013. Melatonin impact into the diurnal and seasonal changes in IL-6 and IL-18 gene expression in blood leukocytes of male Gallus domesticus with experimental peritonitis. J. Anim. Feed Sci., 22: 79-87.
  21. Haldar, C., R. Ahmad, S. Rai, S. Lahiri, S. Sharma and S. Gupta, 2012. Seasonal And Experimental Day Length In Regulation Of Melatonin And Immunity In Indian Tropical Mammal. In: Treatise On Photophysiology. Haldar, C and P. Basu (Ed.). Imagination Publisher, India., pp: 173-191.
  22. Rai, S., 2011. Neuroendocrine Network and Immuneregulation. LAP LAMBERT Academic Publishing, Germany, ISBN-13: 978-3- 8443-1762-6, Pages: 136.
  23. Rai, S and C. Haldar, 2011. Melatonin ameliorates oxidative stress and induces cellular proliferation of lymphoid tissues of a tropical rodent, Funambulus pennanti, during reproductively active phase. Protoplasma, 250: 21-32.
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  24. Haldar, C., S. Gupta, S. Rai, R. Ahmad and R. Yadav, 2010. Pineal Gland And Circulatory Melatonin In Regulation Of Immune Status Of Seasonally Breeding Mammals In “Eco-immunology”. In: “Eco-Immunology” Nelson, R and G. Demas (Ed.). Oxford Univ Press, USA., pp: 326-359.
  25. Rai, S., C. Haldar and R. Singh, 2009. Modulation of immunity in young-adult and aged squirrel, Funambulus pennanti by melatonin and p-chlorophenylalanine. Immun. Ageing, Vol. 6. 10.1186/1742-4933-6-5.
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  26. Haldar, C., S.S. Singh, S. Rai, K. Skwarlo-Sonta, J. Pawlak and M. Singaravel, 2008. Melatonin and immune modulation: Involvement of Neuroendocrine Network. In: Experimental Endocrinology and Reproductive Biology, Haldar, C., M. Singaravel, S.R. Pandi-Perumal and D.P. Cardinelli (Eds.). Taylor & Francis Inc., USA., ISBN: 9781578085187, pp: 297-314.
  27. Singh, S.S., C. Haldar and S. Rai, 2006. Melatonin and differential effect of L-thyroxine on immune system of Indian tropical bird Perdicula asiatica. Gen. Comp. Endocrinol., 145: 215-221.
    PubMed  |  Direct Link  |  
  28. Seema, R and C. Haldar, 2006. Adaptive significance of annual variation in immune parameters and endogenous hormones (melatonin and thyroxine) of tropical rodent Funambulus pennanti. J. Endocrinol. Res., 2: 111-116.
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  29. Lahiri, S., R. Seema and H. Chandana, 2006. Trade off relation between melatonin and gonadal steroid on melatonin receptor (Mel 1a R) expression on lymphoid tissue. J. Endoc. Res., 1: 1-4.
  30. Haldar, C. and S. Rai, 2006. Immunomodulatory role of melatonin: Relationship with bone marrow macrophages and lymphocyte. Proc. Zool. Soc. Calcutta, 59: 87-104.
  31. Haldar, C and S. Rai, 2006. Melatonin And Immunomodulation In Seasonally Breeding Mammals. In: Hormone Biotecnology. Maitra, S.K. (Ed.). Daya Publishing House, India., pp: 189-211.
  32. Rai, S., H. Chandana and S.S. Singh, 2005. Trade-Off between L-Thyroxin and melatonin in immune regulation of the indian palm squirrel, Funambulus pennanti during the reproductively inactive phase. Neuroendocrinol., 82: 103-110.
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  33. Haldar, C., S. Rai and R. Singh, 2004. Melatonin blocks dexamethasone-induced immunosuppression in a seasonally breeding rodent Indian palm squirrel, Funambulus pennanti. Steroids, 69: 367-377.
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  34. Seema, R. and C. Haldar, 2003. Pineal control of immune status and hematological changes in blood and bone marrow of male squirrels (Funambulus pennanti) during their reproductively active phase. Comp. Biochem. Physiol. Part C: Toxicol. Pharmacol., 136: 319-328.
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