Dr. Jaya Prasanthi Rantham Prabhakara
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Dr. Jaya Prasanthi Rantham Prabhakara

Post-doctoral Fellow
University of North Dakota, North Dakota

Highest Degree
Ph.D. in Neurophysiology from Sri Venkarteswara University, Tirupati, India

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Area of Interest:

Biomedical Sciences
100%
Neurosciences
62%
Alzheimer`s Disease
90%
Neurobiology
75%
Neurochemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
18
Abstracts
0

Selected Publications

  1. Marwarha, G., J.R.P. Prasanthi, J. Schommer, B. Dasari and O. Ghribi, 2011. Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus. Mol. Neurodegener., 6: 41-41.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Prasanthi, R.P.J., D.C. Basha and G.R. Reddy, 2010. Protective effects of calcium and zinc on lead induced perturbations in brain acetylcholinesterase activity. Curr. Trends Biotechnol. Pharmacy, 4: 648-659.
    Direct Link  |  
  3. Prasanthi, R.P.J., C.B. Devi, D.C. Basha, N.S. Reddy and G.R. Reddy, 2010. Calcium and zinc supplementation protects lead (Pb)-induced perturbations in antioxidant enzymes and lipid peroxidation in developing mouse brain. Int. J. Dev. Neurosci., 28: 161-167.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Prasanthi, J.R., B. Dasari, G. Marwarha, T. Larson, X. Chen, J.D. Geiger and O. Ghribi, 2010. Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet. Free Radic. Biol. Med., 49: 1212-1220.
    CrossRef  |  PubMed  |  
  5. Marwarha, G., B. Dasari, J.R.P. Prasanthi, J. Schommer and O. Ghribi, 2010. Leptin reduces the accumulation of Aβ and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices. J. Alzheimer's Dis., 19: 1007-1019.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Marwarha, G., B. Dasari, J.P.R. Prabhakara, J. Schommer and O. Ghribi, 2010. β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway. J. Neurochem., 115: 373-384.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Prasanthi, J.R.P., A. Huls, S. Thomasson, A. Thompson, E. Schommer and O. Ghribi, 2009. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on β-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. Mol. Neurodegeneration, 4: 1-1.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Ghribi, O., E. Schommer and J.R.P. Prasanthi, 2009. 27-hydroxycholestrol as the missing link between circulating cholesterol and AD-like pathology. Alzheimer's Dementia, 5: 180-180.
    CrossRef  |  Direct Link  |  
  9. Sharma, S., J.R.P. Prasanthi, E. Schommer, G. Feist and O. Ghribi, 2008. Hypercholesterolemia-induced Aβ accumulation in rabbit brain is associated with alteration in IGF-1 signaling. Neurobiol. Dis., 32: 426-432.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Prasanthi, R.P.J., E. Schommer, S. Thomasson, A. Thompson, G. Feist and O. Ghribi, 2008. Regulation of β-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer`s disease. Mechanisms Ageing Dev., 129: 649-655.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Prabhakara, J.P.R., G. Feist, S. Thomasson, A. Thompson, E. Schommer and O. Ghribi, 2008. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and α-synuclein in human neuroblastoma SH-SY5Y cells. J. Neurochem., 107: 1722-1729.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Ghribi, O., G. Feist and J. Prasanthi, 2008. P4-247: Oxysterols induce Alzheimer's disease-like pathological hallmarks. J. Alzheimer's Assoc., 4: T744-T744.
    CrossRef  |  Direct Link  |  
  13. Prasanthi, R.P.J., G.H. Reddy, C.S. Chetty and G.R. Reddy, 2006. Influence of calcium and zinc on lead-induced alterations in ATPases in the developing mouse brain. J. Pharmacol. Toxicol., 1: 245-252.
  14. Prasanthi, R.P.J., G.H. Reddy and G.R. Reddy, 2006. Calcium or zinc supplementation reduces lead toxicity: Assessment of behavioral dysfunction in young and adult mice. Nutr. Res., 26: 537-545.
    CrossRef  |  Direct Link  |  
  15. Prasanthi, R.P.J., G.H. Reddy, C.B. Devi and G.R. Reddy, 2005. Zinc and calcium reduce lead induced perturbations in the aminergic system of developing brain. BioMetals, 18: 615-626.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. Devi, C.B., G.H. Reddy, R.P.J. Prasanthi, C.S. Chetty and G.R. Reddy, 2005. Developmental lead exposure alters mitochondrial monoamine oxidase and synaptosomal catecholamine levels in rat brain. Int. J. Dev. Neurosci., 23: 375-381.
    CrossRef  |  PubMed  |  Direct Link  |  
  17. Shafeek, A., R.P.J. Prasanthi, G.H. Reddy, C.S. Chetty and G.R. Reddy, 2004. Alterations in acetylcholinesterase and electrical activity in the nervous system of cockroach exposed to the neem derivative, azadirachtin. Ecotoxicol. Environ. Safety, 59: 205-208.
    CrossRef  |  PubMed  |  Direct Link  |  
  18. Shafeek, A., D.A. Kumari, K.S. Sajwan, R.P.J. Prasanthi and G.R. Reddy, 2003. Azadirachtin and fenvalerate induced alterations in the neuronal activity of the cockroach, Periplanata americana. Indian J. Comp. Anim. Physiol., 21: 1-4.