Dr. Kameswaran  Ravichandran

Dr. Kameswaran Ravichandran

Research Scientist
University of Colorado Boulder, USA


Highest Degree
Ph.D. in Pharmacology and Toxicology from University Of Colorado, USA

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Area of Interest:

Pharmacology and Toxicology
100%
Nephrology
62%
Cancer Biology
90%
Adaptogenic
75%
Pharmacy
55%

Education

2011

Ph.D.

University Of Colorado, USA

Pharmacology and Toxicology

Selected Publications

  1. Ravichandran, K., I. Zafar, Z. He, R.B. Doctor, R. Moldovan, A.E. Mullick and C.L. Edelstein, 2014. An mTOR anti-sense oligonucleotide decreases polycystic kidney disease in mice with a targeted mutation in Pkd2. Hum. Mol. Genet., 23: 4919-4931.
    CrossRef  |  PubMed  |  

  2. Ravichandran, K., I. Zafar, A. Ozkok and C.L. Edelstein, 2014. An mTOR kinase inhibitor slows disease progression in a rat model of polycystic kidney disease. Nephrol. Dial. Transplantat., 10.1093/ndt/gfu296.
    CrossRef  |  Direct Link  |  

  3. Ravichandran, K., A. Ozkok, Q. Wang, A.E. Mullick and C.L. Edelstein, 2014. Antisense-mediated angiotensinogen inhibition slows polycystic kidney disease in mice with a targeted mutation in Pkd2. Am. J. Physiol.-Renal Physiol., 10.1152/ajprenal.00478.2014.
    CrossRef  |  

  4. Ravichandran, K. and C.L. Edelstein, 2014. Polycystic kidney disease: A case of suppressed autophagy? Seminars Nephrol., 34: 27-33.
    CrossRef  |  PubMed  |  

  5. Kim, H.J., K. Ravichandran, A. Ozkok, Q. Wang and Z. He et al., 2014. The Water-soluble triptolide derivative PG490-88 protects against Cisplatin-induced acute kidney injury. J. Pharmacol. Exp. Therapeut., 349: 518-525.
    CrossRef  |  PubMed  |  

  6. Ravichandran, K., T.B. Huber, C.L. Edelstein, B. Hartleben and K. Inoki et al., 2012. Emerging role of autophagy in kidney diseases function, diseases and ageing. Autophagy, Vol. 8, .

  7. Raina, K., K. Ravichandran, S. Rajamanickam, K. Hasebroock, N.J. Sarkova and R. Agarwal, 2012. Energy deprivation by inositol hexaphosphate inhibits prostate tumor growth and progression in TRAMP mice. Cancer Prev. Res. (In Press) .

  8. Turkmen, K., J. Martin, A. Akcay, Q. Nguyen and K. Ravichandran, 2011. Apoptosis and autophagy in cold preservation ischemia. Transplantation, 15: 1192-1197.
    Direct Link  |  

  9. Ravichandran, K., F. Belibi, I. Zafar, Z. He and C.L. Edelstein, 2011. mTORC1/2 and rapamycin in female Han: SPRD rats with Polycystic Kidney Disease (PKD).mTORC1/2 and rapamycin in female Han: SPRD rats with Polycystic Kidney Disease (PKD). Am. J. Physiol. Renal. Physiol., 300: 236-244.

  10. Ravichandran, K., A. Tyagi, G. Deep, C. Agarwal and R. Agarwal, 2011. Interleukin-1β induced iNOS expression in human lung carcinoma A549 cells. Involvement of STAT and MAPK pathways. Indian J. Exp. Biol., 49: 840-847.
    Direct Link  |  

  11. Jani, A., M. Zimmerman, J. Martin, L. Lu and K. Ravichandran et al., 2011. Pulsatile perfusion reduces apoptosis in a porcine kidney model of donation after cardiac death (DCD). Transplantation, 91: 169-175.

  12. Belibi, F., I. Zafar, K. Ravichandran, A.B. Segvic, A. Jani, D.A. Ljubanovic and C.L. Edelstein, 2011. Hypoxia-inducible factor 1 α (HIF-1 α) and autophagy in Polycystic Kidney Disease (PKD). Am. J. Physiol. Renal. Physiol., 300: 1235-1243.

  13. Zafar, I., K. Ravichandran, F.A. Belibi, R.B. Doctor and C.L. Edelstein, 2010. Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease. Kidney Int., 78: 754-761.

  14. Ravichandran, K., B. Velmurugan, M. Gu, R.P. Singh and R. Agarwal, 2010. Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice. Clin. Cancer Res., 15-16: 4595-4606.
    PubMed  |  Direct Link  |  

  15. Ravichandran, K., A. Pal and R. Ravichandran, 2010. Effect of indirubin-3-monoxime against lung cancer as evaluated by histological and transmission electron microscopic studies. Microsc. Res. Tech., 73: 1053-1058.
    CrossRef  |  Direct Link  |  

  16. Ravichandran, K. and R. Ravichandran, 2009. Indirubin-3-monoxime induced cell cycle arrest and apoptosis in Hep2 human laryngeal carcinoma cells. Biomed. Pharmacoth., 63: 146-154.