Dr. Kameswaran  Ravichandran

Dr. Kameswaran Ravichandran

Research Scientist
University of Colorado Boulder, USA

Highest Degree
Ph.D. in Pharmacology and Toxicology from University Of Colorado, USA

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Area of Interest:

Pharmacology and Toxicology
Cancer Biology

Selected Publications

  1. Ravichandran, K., I. Zafar, Z. He, R.B. Doctor, R. Moldovan, A.E. Mullick and C.L. Edelstein, 2014. An mTOR anti-sense oligonucleotide decreases polycystic kidney disease in mice with a targeted mutation in Pkd2. Hum. Mol. Genet., 23: 4919-4931.
    CrossRef  |  PubMed  |  
  2. Ravichandran, K., I. Zafar, A. Ozkok and C.L. Edelstein, 2014. An mTOR kinase inhibitor slows disease progression in a rat model of polycystic kidney disease. Nephrol. Dial. Transplantat., 10.1093/ndt/gfu296.
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  3. Ravichandran, K., A. Ozkok, Q. Wang, A.E. Mullick and C.L. Edelstein, 2014. Antisense-mediated angiotensinogen inhibition slows polycystic kidney disease in mice with a targeted mutation in Pkd2. Am. J. Physiol.-Renal Physiol., 10.1152/ajprenal.00478.2014.
    CrossRef  |  
  4. Ravichandran, K. and C.L. Edelstein, 2014. Polycystic kidney disease: A case of suppressed autophagy? Seminars Nephrol., 34: 27-33.
    CrossRef  |  PubMed  |  
  5. Kim, H.J., K. Ravichandran, A. Ozkok, Q. Wang and Z. He et al., 2014. The Water-soluble triptolide derivative PG490-88 protects against Cisplatin-induced acute kidney injury. J. Pharmacol. Exp. Therapeut., 349: 518-525.
    CrossRef  |  PubMed  |  
  6. Ravichandran, K., T.B. Huber, C.L. Edelstein, B. Hartleben and K. Inoki et al., 2012. Emerging role of autophagy in kidney diseases function, diseases and ageing. Autophagy, Vol. 8, .
  7. Raina, K., K. Ravichandran, S. Rajamanickam, K. Hasebroock, N.J. Sarkova and R. Agarwal, 2012. Energy deprivation by inositol hexaphosphate inhibits prostate tumor growth and progression in TRAMP mice. Cancer Prev. Res. (In Press) .
  8. Turkmen, K., J. Martin, A. Akcay, Q. Nguyen and K. Ravichandran, 2011. Apoptosis and autophagy in cold preservation ischemia. Transplantation, 15: 1192-1197.
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  9. Ravichandran, K., F. Belibi, I. Zafar, Z. He and C.L. Edelstein, 2011. mTORC1/2 and rapamycin in female Han: SPRD rats with Polycystic Kidney Disease (PKD).mTORC1/2 and rapamycin in female Han: SPRD rats with Polycystic Kidney Disease (PKD). Am. J. Physiol. Renal. Physiol., 300: 236-244.
  10. Ravichandran, K., A. Tyagi, G. Deep, C. Agarwal and R. Agarwal, 2011. Interleukin-1β induced iNOS expression in human lung carcinoma A549 cells. Involvement of STAT and MAPK pathways. Indian J. Exp. Biol., 49: 840-847.
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  11. Jani, A., M. Zimmerman, J. Martin, L. Lu and K. Ravichandran et al., 2011. Pulsatile perfusion reduces apoptosis in a porcine kidney model of donation after cardiac death (DCD). Transplantation, 91: 169-175.
  12. Belibi, F., I. Zafar, K. Ravichandran, A.B. Segvic, A. Jani, D.A. Ljubanovic and C.L. Edelstein, 2011. Hypoxia-inducible factor 1 α (HIF-1 α) and autophagy in Polycystic Kidney Disease (PKD). Am. J. Physiol. Renal. Physiol., 300: 1235-1243.
  13. Zafar, I., K. Ravichandran, F.A. Belibi, R.B. Doctor and C.L. Edelstein, 2010. Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease. Kidney Int., 78: 754-761.
  14. Ravichandran, K., B. Velmurugan, M. Gu, R.P. Singh and R. Agarwal, 2010. Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice. Clin. Cancer Res., 15-16: 4595-4606.
    PubMed  |  Direct Link  |  
  15. Ravichandran, K., A. Pal and R. Ravichandran, 2010. Effect of indirubin-3-monoxime against lung cancer as evaluated by histological and transmission electron microscopic studies. Microsc. Res. Tech., 73: 1053-1058.
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  16. Ravichandran, K. and R. Ravichandran, 2009. Indirubin-3-monoxime induced cell cycle arrest and apoptosis in Hep2 human laryngeal carcinoma cells. Biomed. Pharmacoth., 63: 146-154.