Dr. Vasudevan Mani
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Dr. Vasudevan Mani

Associate Professor
Department of Pharmacology & Toxicology, Qassim University, Buraidah, Kingdom of Saudi Arabia

Highest Degree
Ph.D. in Pharmaceutical Sciences from Guru Jambheshwar University of Science and Technology, India

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Biography

Dr. Vasudevan Mani is currently working as Associate Professor at University Teknologi Mara, Malaysia. He obtained his PhD in Pharmaceutical Sciences from Guru Jambheshwar University of Science & Technology, Hisar, Haryana, India. He is professional member of many Indian socities and associations. His area of interest related to Learning and Memory, Alzheimer’s disease, Anti-cancer, Hepatoprotective and Antioxidant activity, Phytochemistry, Toxicological studies. He also supervised number of PhD and MS students. He has published (17) articles in journals (1) book and (6) chapters in books. He is also member of editor board and also serving as reviewer in number of national and international journals. Dr. Vasudevan Mani received number of honors include Senior Research Fellow, Silver Award at Bio-innovation Award, Gold Medal, Bank Islam Malaysia Special Award and Best Poster Award.

Area of Interest:

Pharmacology and Toxicology
100%
Alzheimer`s Disease
62%
Anti-Cancer
90%
Hepatoprotective Activity
75%
Phytochemistry
55%

Research Publications in Numbers

Books
2
Chapters
7
Articles
138
Abstracts
4

Selected Publications

  1. Prakash, A., J. Kalra, M. Vasudevan, K. Ramasamy and A.B.A. Majeed, 2015. Pharmacological approaches for Alzheimer's disease: Neurotransmitter as drug targets. Expert Rev. Neurotherapeutics, 15: 53-71.
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  2. Prakash, A., A. Kumar, L.C. Ming, M. Vasudevan and A.B.A. Majeed, 2015. Modulation of the nitrergic pathway via activation of PPAR-γ contributes to the neuroprotective effect of pioglitazone against streptozotocin-induced memory dysfunction. J. Mol. Neurosci., (In Press). 10.1007/s12031-015-0508-7.
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  3. Deep, A., P. Kumar, M. Kumar, R. Kalavathy and M. Vasudevan et al., 2015. Synthesis, antimicrobial, anticancer evaluation of 2-(aryl)-4-thiazolidinone derivatives and their QSAR studies. Curr. Topics Med. Chem., 15: 990-1002.
    PubMed  |  
  4. Ahmad, A., K. Ramasamy, A.B.A. Majeed and V. Mani, 2015. Enhancement of β-secretase inhibition and antioxidant activities of tempeh, a fermented soybean cake through enrichment of bioactive aglycones. Pharm. Biol., 53: 758-766.
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  5. Vasudevan, M., A. Aliya, R. Kalavathy, S.M. Lim and B.A.M. Abu, 2014. Murraya koenigii Leaves and Usage in Dementia. In: Diet and Nutrition Dementia in Cognitive Decline, Martin, C.R. and V.R. Preedy (Eds.). Chapter 97, Elsevier, London, ISBN: 9780124078246, pp: 1039-1045.
  6. Siong, M.L., Z.R. Muhammad, A.A.A. Nor, M. Vasudevan, B.A.M. Abu and R. Kalavathy, 2014. Probiotics and Neuroprotection. In: Diet and Nutrition Dementia in Cognitive Decline, Martin, C.R. and V.R. Preedy (Eds.). Chapter 79, Elsevier, London, ISBN: 9780124078246, pp: 859-868.
  7. Saini, M., P. Kumar, M. Kumar, K. Ramasamy and V. Mani et al., 2014. Synthesis, in vitro antimicrobial, anticancer evaluation and QSAR studies of N′-(substituted)-4-(butan-2-lideneamino)benzohydrazides. Arabian J. Chem., 7: 448-460.
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  8. Rohilla, P., A. Deep, M. Kamra, B. Narasimhan and K. Ramasamy et al., 2014. Synthesis, antimicrobial and anticancer evaluation of N′-(substituted benzylidene)-2-(benzo [d] oxazol-3 (2 H)-yl) acetohydrazide derivatives. Drug Res., 64: 505-509.
  9. Muneersha, T.K.M., T.E.F. Habeeba, M. Musambil, P.V. Mirshad, O.M.F. Rahiman and M. Vasudevan, 2014. The effect of polyherbal formulation DIA7 on fasting blood glucose level in alloxan induced diabetic rats. Der Pharmacia Lettre, 6: 215-221.
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  10. Kumar, P., B. Narasimhan, K. Ramasamy, V. Mani, R.K. Mishra and A.B.A. Majeed, 2014. Synthesis, antimicrobial, anticancer evaluation and QSAR studies of 2/3-bromo-N′-(substituted benzylidene/3-phenylallylidene)benzohydrazides. Arabian J. Chem. 10.1016/j.arabjc.2014.05.010.
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  11. Kumar, M., K. Ramasamy, V. Mani, R.K. Mishra, A.B.A. Majeed, E. de Clercq and B. Narasimhan, 2014. Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides. Arabian J. Chem., 7: 396-408.
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  12. Kumar, M., B. Narasimhan, P. Kumar, K. Ramasamy, M. Vasudevan, R.K. Mishra and A.B.A. Majeed, 2014. 4-(1-Aryl-5-chloro-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substitutedbenzene sulfonamides: Synthesis, antimicrobial, anticancer evaluation and QSAR studies. Arabian J. Chem., 7: 436-447.
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  13. Ariffin, S.A., K. Ramasamy, P. Davis, V. Mani and M.A. Abdulla, 2014. Safety of Malaysian marine endophytic fungal extract S2 from a brown seaweed Turbinaria conoides. J. Coastal Life Med., 2: 527-534.
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  14. Ahmad, A., K. Ramasamy, S.M. Jaafar, A.B.A. Majeed and V. Mani, 2014. Total isoflavones from soybean and tempeh reversed Scopolamine-induced amnesia, improved cholinergic activities and reduced neuroinflammation in brain. Food Chem. Toxicol., 65: 120-128.
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  15. Mutalip, S.S.M., G.K.S. Singh, A.M. Shah, M. Mohamad, M. Vasudevan and S.N. Hussin, 2013. Histological changes in testes of rats treated with testosterone, nandrolone and stanozolol. Iran. J. Reprod. Med., 11: 653-658.
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  16. Mani, V., K. Ramasamy, A. Ahmad, S.N. Wahab and S.M. Jaafar et al., 2013. Effects of the total alkaloidal extract of murraya koenigii leaf on oxidative stress and cholinergic transmission in aged mice. Phytother. Res., 27: 46-53.
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  17. Mani, V., K. Ramasamy and A.B.A. Majeed, 2013. Anti-inflammatory, analgesic and Anti-ulcerogenic effect of total alkaloidal extract from Murraya koenigii leaves in animal models. Food Function, 4: 557-567.
  18. Kumar, P., B. Narasimhan, K. Ramasamy, V. Mani, R.K. Mishra, A.B.A. Majeed and E. de Clercq, 2013. N'-[4-[(Substituted imino)methyl]benzylidene]-substituted benzohydrazides: Synthesis, antimicrobial, antiviral and anticancer evaluation and QSAR studies. Monatshefte Chemie-Chem. Monthly, 144: 825-849.
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  19. Kumar, M., B. Narasimhan, K. Ramasamy, V. Mani, R.K. Mishra and A.B.A. Majeed, 2013. Synthesis, antimicrobial and cytotoxic evaluation of 4-(1-aryl-5-halo-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulphonamides. Arabian J. Chem., 10.1016/j.arabjc.2013.11.009.
    CrossRef  |  
  20. Kumar, H., P. Kumar, B. Narasimhan, K. Ramasamy, V. Mani, R.K. Mishra and A.B. Abdul Majeed, 2013. Synthesis, in vitro antimicrobial, antiproliferative and QSAR studies of N-(substituted phenyl)-2/4-(1H-indol-3-ylazo)-benzamides. Med. Chem. Res., 22: 1957-1971.
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  21. Deep, A., B. Narasimhan, K. Ramasamy, M. Vasudevan, R.K. Mishra and A.B.A. Majeed, 2013. Synthesis, antimicrobial, anticancer evaluation and QSAR studies of Thiazolidin-4-ones clubbed with quinazolinone. Curr. Topics Med. Chem., 13: 2034-2046.
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  22. Zakaria, Z.A., E.E. Abdul Hisam, M. Norhafizah, M.S. Rofiee, F. Othman, A.H. Hasiah and M. Vasudevan, 2012. Methanol extract of Bauhinia purpurea leaf possesses Anti-ulcer activity. Med. Principles Pract., 21: 476-482.
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  23. Sigroha, S., B. Narasimhan, P. Kumar, A. Khatkar and K. Ramasamy et al., 2012. Design, synthesis, antimicrobial, anticancer evaluation and QSAR studies of 4-(substituted benzylidene-amino)-1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-ones. Med. Chem. Res., 21: 3863-3875.
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  24. Sharma, S.K., P. Kumar, B. Narasimhan, K. Ramasamy, V. Mani, R.K. Mishra and A.B.A. Majeed, 2012. Synthesis, antimicrobial, anticancer evaluation and QSAR studies of 6-methyl-4-[1-(2-substituted-phenylamino-acetyl)-1H-indol-3-yl]-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl esters. Eur. J. Med. Chem., 48: 16-25.
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  25. Mani, V., K. Ramasamy, A. Ahmad, M. Parle, S.A.A. Shah and A.B.A. Majeed, 2012. Protective effects of total alkaloidal extract from Murraya koenigii leaves on experimentally induced dementia. Food Chem. Toxicol., 50: 1036-1044.
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  26. Mani, V., M. Parle, K. Ramasamy, A. Majeed and A. Bakar, 2011. Reversal of memory deficits by Coriandrum sativum leaves in mice. J. Sci. Food Agric., 91: 186-192.
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  27. Giridharan, V.V., R.A. Thandavarayan, V. Mani, T. Ashok Dundapa, K. Watanabe and T. Konishi, 2011. Ocimum sanctum Linn. leaf extracts inhibit acetylcholinesterase and improve cognition in rats with experimentally induced dementia. J. Med. Food, 14: 912-919.
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  28. Vasudevan, M., M. Parle, R. Kalavathy and A.M. Abu Bakar, 2010. Anti-dementia potential of Daucus carota seed extract in rats. Pharmacologyonline, 1: 552-565.
  29. Vasudevan, M. and M. Parle, 2009. Antiamnesic potential of Murraya koenigii leaves. Phytother. Res., 23: 308-316.
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  30. SivaKumar, T., K. Srinivasan, R. Rajavel, M. Vasudevan, M. Ganesh, K. Kamalakannan and P. Mallika, 2009. Isolation of chemical constituents from Prosopis juliflora bark and Anti-inflammatory activity of its methanolic extracts. J. Pharmacy Res., 2: 551-556.
  31. Saravanakumar, A., K. Venkateshwaran, J. Vanitha, M. Ganesh, M. Vasudevan and T. Sivakumar, 2009. Evaluation of antibacterial activity, phenol and flavonoid contents of Thespesia populnea flower extracts. Pak. J. Pharm. Sci., 23: 282-286.
    PubMed  |  
  32. Nandhakumar, J., S. Sengottuvelu, M.G. Tyagi, P.P. Sethumathi and D. Karthikeyan et al., 2009. Efficacy, tolerability and safety of a multicomponent antiinflammatory with glucosamine hydrochloride vs glucosamine sulfate vs an NSAID in the treatment of knee osteoarthritis-A randomized, prospective, double-blind, comparative study. Integrative Med.: Clin. J., 8: 32-38.
  33. Mani, V. and M. Parle, 2009. Memory-enhancing activity of Coriandrum sativum in rats. Pharmacologyonline, 2: 827-839.
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  34. Kumar, A.S., K. Venkateshwaran, J. Vanitha, V.S. Saravanan, M. Ganesh, M. Vasudevan and T. Sivakumar, 2009. Synergistic activity of methanolic extract of Thespesia populnea (Malvaceae) flowers with oxytetracycline. Bangladesh J. Pharmacol., 4: 13-16.
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  35. Vasudevan, M., M. Parle, S. Sengottuvelu and T. Shanmugapriya, 2008. Nootropic potential of Murraya koenigii leaves in rats. Oriental Pharm. Exp. Med., 8: 365-373.
  36. Vasudevan, M. and M. Parle, 2008. Evidence of Anti-demential potential of Abana, an Indian ayurvedic Poly-herbal formulation in rats. Pharmacologyonline, 1: 439-454.
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  37. Sengottuvelu, S., S. Duraisami, R. Duraisami, J. Nandhakumar, M. Vasudevan and T. Sivakumar, 2008. Hepatoprotectiive activity of Trianthema decandra on carbon Tetrachloride-induced hepatotoxicity in rats. Int. J. Green Pharmacy, 2: 122-125.
  38. Sengottuvelu, S., S. Duraisami, J. Nandhakumar, R. Duraisami and M. Vasudevan, 2008. Hepatoprotective activity of Camellia sinensis and its possible mechanism of action. Iran. J. Pharmacol. Therapeut., 7: 9-14.
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  39. Kumar, A.S., K. Venkateshwaran, S. Vanitha, M. Ganesh, M. Vasudevan and T. Sivakumar, 2008. Synergism between methanolic extract of Sesbania grandiflora (fabaceae) flowers and oxytetracycline. Pharmacologyonline, 3: 6-11.
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  40. Jothivel, N., S. Singaravel, K. Deivasigamani, M. Vasudevan, S. Sundaram, N. Sambasivam and S. Thangavel, 2008. Follow-up of combination of chloroquine with Anti-viral drugs treated chronic hepatitis 'B' patients for their carrier state. Res. J. Pharm. Technol., 1: 259-259.
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  41. Ganesh, M., M. Vasudevan, K. Kamalakannan, A.S. Kumar, M. Vinoba, S. Gaguly and T. Sivakumar, 2008. Anti-inflammatory and analgesic effects of Pongamia glabra leaf gall extract. Pharmacologyonline, 1: 497-512.
  42. Vasudevan, M., K.K. Gunman and M. Parle, 2007. Antinociceptive and anti-inflammatory effects of Thespesia populnea bark extract. J. Ethnopharmacol., 109: 264-270.
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  43. Vasudevan, M. and M. Parle, 2007. Memory-enhancing activity of Thespesia populnea in Rats. Pharm. Biol., 45: 267-273.
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  44. Vasudevan, M. and M. Parle, 2007. Memory enhancing activity of Anwala churna (Emblica officinalis Gaertn.): An ayurvedic preparation. Physiol. Behav., 91: 46-54.
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  45. Vasudevan, M. and M. Parle, 2007. Effect of Anwala churna (Emblica officinalis Gaertn.): An ayurvedic preparation on memory deficit rats. Yakugaku Zasshi, 127: 1701-1707.
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  46. Sengottuvelu, S., D. Srinivasan, R. Duraisamy, M. Vasudevan, J. Nandhakumar, D. Karthikeyan and T. Sivakumar, 2007. In vitro anthelmintic activity of Cleome viscose against Haemonchus contortus. Antiseptic, 104: 588-589.
  47. Sengottuvelu, S., D. Srinivasan, M. Vasudevan, J. Nandhakumar, R. Duraisamy, D. Karthikeyan and T. Sivakumar, 2007. Wound healing effect of aqueous extract of Azadirachta indica leaves in alloxan induced diabetic rats. Antiseptic, 104: 377-379.
  48. Parle, M. and M. Vasudevan, 2007. Anti-alzheimer potential of Abana®: An Indian ayurvedic Poly-herbal formulation. J. Health Sci., 53: 43-52.
  49. Vasudevan, M., K.K. Gunnam and M. Parle, 2006. Antinociceptive and Anti-inflammatory properties of Daucus carota seeds extract. J. Health Sci., 52: 598-606.
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  50. Vasudevan, M. and M. Parle, 2006. Pharmacological evidence for the potential of Daucus carota in the management of cognitive dysfunctions. Biol. Pharm. Bull., 29: 1154-1161.
    PubMed  |  
  51. Vasudevan, M. and M. Parle, 2006. Pharmacological actions of Thespesia populnea relevant to Alzheimer's disease. Phytomedicine, 13: 677-687.
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  52. Parle, M., N. Singh and M. Vasudevan, 2006. Regular rehearsal helps in consolidation of long term memory. J. Sports Sci. Med., 5: 80-88.
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  53. Parle, M., M. Vasudevan and N. Singh, 2005. Swim everyday to keep dementia away. J. Sports Sci. Med., 4: 37-46.
  54. Ilavarasan, R., M. Vasudevan, S. Anbazhagan, S. Venkataraman and S.K. Sridhar, 2003. Hepatoprotective activity of Thespesia populnea bark extracts against carbon Tetrachloride-induced liver toxicity in rats. Nat. Prod. Sci., 9: 83-86.
  55. Ilavarasan, R., M. Vasudevan, S. Anbazhagan and S. Venkataraman, 2003. Antioxidant activity of Thespesia populnea bark extracts against carbon Tetrachloride-induced liver injury in rats. J. Ethnopharmacol., 87: 227-230.