Dr. Aukunuru Venkata Jithan

Dr. Aukunuru Venkata Jithan

Head of Department
Omega College Of Pharmacy, India

Highest Degree
Ph.D. in Pharmaceutical Sciences from University of Nebraska Medical Center, Omaha, USA

My URL
https://livedna.org/91.840

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Area of Interest:

Biomedical Sciences
100%
Pharmaceutical Sciences
62%
Pharmacology and Toxicology
90%
Pharmacokinetics
75%
Drug Absorption
55%

Selected Publications

  1. Reddy, B.C.S., K. Bommineni and J. Aukunuru, 2019. Parenteral administered sustained release piperine microspheres intended to treat liver fibrosis. Int. J. Pharm. Sci. Res., 10: 1935-1943.
  2. Tadakapally, R., M. Habibuddin and J. Aukunuru, 2018. Preparation and characterization of PEG-Albumin-Paclitaxel (PAP)nanoparticles intended to treat breast cancer. Int. J. Chem. Tech. Res., 11: 143-145.
  3. Ghule, P., R. Gilhotra, A. Jithan, S. Bairagi and A. Aher, 2018. Amorphous solid dispersion: a promising technique for improving oral bioavailability of poorly water-soluble drugs-review. SA Pharm. J., 85: 50-56.
    Direct Link  |  
  4. Devara, R., M. Habibuddin, K. Thadkala and J. Aukunuru, 2018. Preparation and evaluation of controlled release parenteral nanosuspensions of anastrazole. Int. J. Pharm. Tech. Res., 11: 96-107.
    CrossRef  |  Direct Link  |  
  5. Devara, R., M. Habibuddin and J. Aukunuru, 2018. Enhancement of dissolution rate of poorly soluble itraconazole by nanosuspension technology: Its preparation and evaluation studies. Asian J. Pharm. Clin. Res., 11: 414-421.
  6. Das, S., S. Das, D. Pattanayak, C. Hossain, A.V. Jithan, 2018. Formulation and characterization of paracetamol co-crystals for enhanced bioavailability. J. Pharm. Drug Deliv. Res., Vol. 7. .
    Direct Link  |  
  7. Aukunuru, J. and C. Bonepally, 2018. Optimization of encapsulation efficiency of piperine in soya-lecithin multilamellar vesicles. Int. J. Chem. Tech. Res., 10: 723-729.
    Direct Link  |  
  8. Nallaguntla, L., Y.I. Muzib, J. Aukunuru and U. Balekari, 2017. Novel nanoparticles for the oral delivery of low molecular weight heparin: In vitro and in vivo assessment. Asian J. Pharmaceut. Clin. Res., 10: 254-261.
    Direct Link  |  
  9. Thadkala, K., M.P. Reddy, J. Aukunuru and C. Sailu, 2017. Preparation and characterization of sustained release ranolazine microcapsules by W/O emulsification-solvent evaporation technique. Int. J. Chem. Tech. Res., 10: 1182-1184.
    Direct Link  |  
  10. Thadakapally, R., A. Aafreen, J. Aukunuru, M. Habibuddin and S. Jogala, 2016. Preparation and characterization of PEG-albumin-curcumin nanoparticles intended to treat breast cancer. Indian J. Pharmaceut. Sci., 78: 65-72.
    PubMed  |  
  11. Lavanya, N., Y.I. Muzib, J. Aukunuru and U. Balekari, 2016. Preparation and evaluation of a novel oral delivery system for low molecular weight heparin. Int. J. Pharmaceut. Invest., 6: 148-157.
    CrossRef  |  Direct Link  |  
  12. Jogala, S., S.S. Rachamalla and J. Aukunuru, 2016. Development of PEG-PLGA based intravenous Low Molecular Weight Heparin (LMWH) nanoparticles intended to treat venous thrombosis. Curr. Drug Delivery, 13: 698-710.
    Direct Link  |  
  13. Jogala, S., J. Aukunuru and K.M. Chinnala, 2016. Novel subcutaneous sustained release nanoparticles encapsulating Low Molecular Weight Heparin (LMWH): Preparation, characterization and evaluation. Int. J. Pharm. Pharmaceut. Sci., 8: 264-268.
    Direct Link  |  
  14. Yerragunta, B., S. Jogala, K.M. Chinnala and J. Aukunuru, 2015. Development of a novel 3-month drug releasing risperidone microspheres. J. Pharm. BioAllied Sci., 7: 37-44.
    CrossRef  |  Direct Link  |  
  15. Jogala, S., S. Rachamalla and J. Aukunuru, 2015. Development of subcutaneous sustained release nanoparticles encapsulating low molecular weight heparin. J. Adv. Pharmaceut. Technol. Res., 6: 58-64.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. Devara, R.K., H.U.R. Mohammad, B. Rambabu, J. Aukunuru and M. Habibuddin, 2015. Preparation, optimization and evaluation of intravenous curcumin nanosuspensions intended to treat liver fibrosis. Turk. J. Pharmaceut. Sci., 12: 8-24.
    Direct Link  |  
  17. Bhogam, B., S. Chigiri, S. Aukunuru and Shayeda, 2015. Preparation, characterization and evaluation of anti-inflammatory activity of dexamethasone topical liposomal gel formulation. Am. J. Pharm Tech Res., 5: 315-331.
    Direct Link  |  
  18. Bandigari, V., K. Thadkala, R.K. Devara and J. Aukunuru, 2015. Preparation and evaluation of orodispersable tablets of carbamazepine using different superdisintegrating agents. Int. J. Pharm Tech Res., 7: 438-447.
  19. Thadkala, K., P.K. Nanam, B. Rambabu, C. Sailu and J. Aukunuru, 2014. Preparation and characterization of amorphous ezetimibe nanosuspensions intended for enhancement of oral bioavailability. Int. J. Pharmaceut. Invest., 4: 131-137.
    CrossRef  |  Direct Link  |  
  20. Tadudari, A., K. Thadkala, J. Kota and J. Aukunuru, 2014. Formulation, characterisation and evaluation of sustained release microcapsules of gemifloxacin. Int. J. PharmTech Res., 6: 1170-1179.
  21. Sappidi, S., K. Thadkala, J. Kota and J. Aukunuru, 2014. Preparation and characterization of ethyl cellulose microspheres encapsulating metformin hydrochloride and glipizide. Der Pharma Lettre, 6: 213-226.
    Direct Link  |  
  22. Raju, A., A.J. Reddy, J. Satheesh and A.V. Jithan, 2014. Preparation and characterisation of nevirapine oral nanosuspensions. Indian J. Pharmaceut. Sci., 76: 62-72.
    CrossRef  |  Direct Link  |  
  23. Navitha, A., S. Jogala, C. Krishnamohan and J. Aukunuru, 2014. Development of novel risperidone implants using blends of polycaprolactones and in vitro in vivo correlation studies. J. Adv. Pharmaceut. Technol. Res., 5: 84-89.
    CrossRef  |  Direct Link  |  
  24. Nanam, P.K., K. Thadkala, C. Sailu and J. Aukunuru, 2014. Investigation of various practical techniques to enhance dissolution of ezetimibe from oral tablets: A comparative study. J. Young Pharmacists, 6: 8-15.
    Direct Link  |  
  25. Kemisetti, D.P., S. Manda, J. Aukunuru, K.M. Chinnala and N.K. Rapaka, 2014. Synthesis of prodrugs of mefenamic acid and their in vivo evaluation. Int. J. Pharm. Pharmaceut. Sci., 6: 437-442.
    Direct Link  |  
  26. Kemisetti, D., S. Manda, S.R. Satla, J. Aukunuru and N.K. Rapaka, 2014. Preparation of aceclofenac prodrugs, in vitro and in vivo evaluation. Int. J. Pharma Bio. Sci., 5: 239-253.
    Direct Link  |  
  27. Kemisetti, D., S. Manda, N.K. Rapaka and A.V. Jithan, 2014. Synthesis of nimesulide conjugates, in vitro and in vivo evaluation. Der. Pharm. Chemica, 6: 317-329.
    Direct Link  |  
  28. Kemisetti, D., S. Manda, J. Aukunuru and N.K. Rapaka, 2014. Polymeric prodrugs of diclofenac and in vivo evaluation. Int. J. Chem. Tech. Res., 6: 2637-2644.
  29. Shiny, J., T. Ramchander, P. Goverdhan, M. Habibuddin and J.V. Aukunuru, 2013. Development and evaluation of a novel biodegradable sustained release microsphere formulation of paclitaxel intended to treat breast cancer. Int. J. Pharmaceut. Invest., 3: 119-125.
    CrossRef  |  Direct Link  |  
  30. Elthuri, I., C. Bonepally, S. Kokkula, R. Thadkapally and J. Aukunuru, 2013. Preparation and optimization of kupffer cell targeted catechin loaded spherical particles. Turk. J. Pharmaceut. Sci., 10: 35-47.
    Direct Link  |  
  31. Bonepally, C.R., S.J. Gandey, K. Bommineni, K.M. Gottumukkala and J. Aukunuru, 2013. Preparation, characterisation and in vivo evaluation of silybin nanoparticles for the treatment of liver fibrosis. Trop. J. Pharmaceut. Res., 12: 1-6.
    CrossRef  |  Direct Link  |  
  32. Bonepally, C.R., J. Aukunuru and K.M. Gottumukkala, 2013. Parenteral sustained release silybin microparticles intended for treatment of liver fibrosis. Int. J. Pharm. Biol. Sci., 3: 8-16.
  33. Path, S., P. Dara, S.K. Yamsani, R. Thadkapally and J. Aukunuru, 2012. Development and evaluation of oral elementary osmotic pump tablets for ropinirole hydrochloride. Indian Drugs, 49: 23-30.
  34. Madhavi, M., K. Madhavi and A.V. Jithan, 2012. Preparation and in vitro in vivo characterization of curcumin microspheres intended to treat colon cancer. J. Pharm. BioAllied Sci., 4: 164-171.
    CrossRef  |  Direct Link  |  
  35. Setty, C.M., M. Radhika, V.R.M. Gupta, M.V.R. Reddy and A.V. Jithan, 2011. Effect of tablet processing and formulation factors on disintegration and dissolution of aceclofenac tablets. Int. J. Pharmaceut. Sci. Nanotechnol., 3: 1240-1251.
    Direct Link  |  
  36. Koppisetti, V.S. and J. Aukunuru, 2011. Physicochemical stability of NNDBDC-a complete synthetic derivative of curcumin. J. Pharm. Res., 1: 761-762.
    Direct Link  |  
  37. Konatham, S., B. Reddy and A. Jithan, 2011. Enhanced liver delivery and sustained release of curcumin with drug loaded nanoparticles after intravenous administration in rats. Asian J. Pharmaceut. Res. Health Care, 3: 99-108.
    CrossRef  |  Direct Link  |  
  38. Jithan, A.V., K. Madhavi, M. Madhavi and K. Prabhakar, 2011. Preparation and characterization of albumin nanoparticles encapsulating curcumin intended for the treatment of breast cancer. Int. J. Pharmaceut. Invest., 1: 119-125.
    CrossRef  |  Direct Link  |  
  39. Aukunuru, J., P. Tyagi, C. Durairaj and U.B. Kompella, 2011. Drug Suspension Development for the Back of the Eye. In: Drug Product Development for the Back of the Eye, Kompella, U. and H. Edelhauser (Eds.)., Springer Publications, New York, ISBN: 978-1-4419-9919-1, pp: 449-468.
  40. Anampally, S., S.K. Mankala, P.K. Gogu and J. Aukunur, 2011. Development of ropinirole (free base) transdermal patch using blends of hydroxypropyl methylcellulose/eudragits and it's in vitro/in vivo characterization. Asian J. Pharmaceut. Res. Health Care, 3: 89-98.
    in vitro/in vivo characterization.' target='_blank'>CrossRef  |  in vitro/in vivo characterization.' target='_blank'>Direct Link  |  
  41. Swathi, M., J. Aukunuru and Y.M. Rao, 2010. Formulation, characterization and evaluation of granisetron buccal patches. J. Pharm. Chem., 4: 109-113.
    Direct Link  |  
  42. Swapna, N. and A.V. Jithan, 2010. Preparation, characterization in vivo evaluation of parenteral sustained release microsphere formulation of zopiclone. J. Young Pharmacists, 2: 223-228.
    CrossRef  |  Direct Link  |  
  43. Sankavarapu, V. and J. Aukunuru, 2010. Development and evaluation of zero order sustained release matrix type transdermal films of ibuprofen. J. Global Pharma Technol., 2: 51-58.
  44. Konatham, S., P. Kumar and J. Aukunuru, 2010. Synthesis and screening of antidiabetic activity of some novel curcumin analogues. Int. J. Pharma Bio Sci., 1: 1-12.
    Direct Link  |  
  45. Konatham, S., H.K. Nyathani, C.R. Bonepally, P.K. Yannamaneni and J. Aukunuru, 2010. Liposomal delivery of curcumin to liver. Turk. J. Pharmaceut. Sci., 7: 89-98.
    Direct Link  |  
  46. Jithan, A.V. and M. Swathi, 2010. Development of topical diclofenac sodium liposomal gel for better anti-inflammatory activity. Int. J. Pharm. Sci. Nanotech., 3: 986-993.
  47. Gogu, P.K. and A.V. Jithan, 2010. Preparation and in vitro/in vivo characterization of spray dried microsphere formulation encapsulating 4-chlorocurcumin. Indian J. Pharmaceut. Sci., 72: 346-352.
    CrossRef  |  Direct Link  |  
  48. Garipelli, N., B.M. Reddy and A.V. Jithan, 2010. Synthesis and evaluation of clozapine and its related compounds. Int. J. Pharm. Sci. Nanotechnol., 2: 762-767.
    Direct Link  |  
  49. Gaddam, N. and J. Aukunuru, 2010. Systemic delivery of diclofenac sodium after topical application of gels incorporated with drug-loaded Solid Lipid Nanoparticles (SLN). Asian J. Pharmaceut. Res. Health Care, 2: 177-187.
    CrossRef  |  Direct Link  |  
  50. Aukunuru, J. and V. Sankavarapu, 2010. Pharmacokinetics and in vitro and in vivo correlation of NN-dimethylaminocurcumin (NNDMAC) loaded polycaprolactone microspheres in rats. Curr. Trends Biotechnol. Pharm., 4: 578-588.
    Direct Link  |  
  51. Anuradha, C.A. and J. Aukunuru, 2010. Preparation, characterisation and in vivo evaluation of Bis-Demethoxy Curcumin Analogue (BDMCA) nanoparticles. Trop. J. Pharmaceut. Res., 9: 51-58.
    Direct Link  |  
  52. Anampelli, S. and J. Aukunuru, 2010. Development of ganisetron transdermal films: In vitro and ex vivo characterization. Indian Drugs, 47: 21-28.
  53. Shankeshi, J. and J. Aukunuru, 2009. Preparation, characterization and evaluation of antidiabetic activity of a liposomal formulation encapsulating curcumin, an ayurvedic natural product. Pharmacist, 3: 105-125.
  54. Sankavarapu, V. and J. Aukunuru, 2009. Preparation, characterization and evaluation of hepatoprotective activity of NNDMAC biodegradable parenteral sustained release microspheres. J. Pharmaceut. Res. Health Care, 1: 240-259.
    CrossRef  |  Direct Link  |  
  55. Garipelli, N., R.B. Sunoj, B.M. Reddy, A.V. Jithan and C. Runja, 2009. Quantification of intramolecular hydrogen bond in neurotransmitter dopamine. Int. J. Pharm. Sci. Nanotechnol., 2: 671-674.
    Direct Link  |  
  56. Aukunuru, J., S. Joginapally, N. Gaddam, M. Burra and C.R. Bonepally, 2009. Preparation, characterization and evaluation of hepatoprotective activity of an intravenous liposomal formulation of Bis-Demethoxy Curcumin Analogue (BDMCA). Int. J. Drug Dev. Res., 1: 37-46.
    Direct Link  |  
  57. Aukunuru, J., K.M. Chinnala and V. Guduri, 2009. Development of a novel transdermal ibuprofen ointment. Curr. Trends Biotechnol. Pharmacy, 3: 97-104.
    Direct Link  |  
  58. Aukunuru, J., K. Eedula, V. Pasham, V. Katla and K.S. Reddy, 2009. Synthesis of novel piperonal derivatives and evaluation of their anticonvulsant activity using a nanoparticular formulation. Int. J. Pharm. Sci. Nanotechnol., 2: 435-442.
    Direct Link  |  
  59. Aukunuru, J. and C. Runja, 2009. Synthesis and evaluation of antidepressant activity of some curcumin-like compounds. Pharm. Commun., 2: 38-41.
  60. Viswanath, G., A. Jithan and V.M. Reddy, 2008. Development of new delivery strategies to increase bioavailability of curcumin. Int. J. Pharm. Sci. Nanotechnol., 1: 335-340.
    Direct Link  |  
  61. Sridhar, A., A.V. Jithan and V.M. Reddy, 2008. Comparative pharmacokinetics of free and liposome-encapsulated catechin after intravenous and intraperitoneal administration. Int. J. Pharm. Sci. Nanotechnol., 1: 152-159.
    Direct Link  |  
  62. Jithan, A.V., C.K. Mohan and M.V. Devi, 2008. Development and evaluation of a chloramphenicol hypertonic ophthalmic solution. Indian J. Pharm. Sci., 70: 66-70.
    CrossRef  |  PubMed  |  Direct Link  |  
  63. Ganji, S., K.M. Chinnala and J. Aukunuru, 2008. Preparation, excipient properties and pharmacological activities of okra mucilage. Pharmacog. Mag., 4: 73-77.
  64. Ganji, S. and J. Aukunuru, 2008. Formulation, excipient properties and pharmacological activities of catechin liposomes. Pharmacog. Magazine, 4: 121-126.
    Direct Link  |  
  65. Chandrasekhar, R., Bonepally, J. Aukunuru, N.R. Yellu and M.R. Vanga, 2008. Fabrication and investigations on hepatoprotective activity of sustained release biodegradable piperine microspheres. Int. J. Pharm. Sci. Nanotechnol., 1: 87-96.
    Direct Link  |  
  66. Shankeshi, J., J. Aukunuru and M.R. Vanga, 2007. Preclinical assessment of sustained release biodegradable curcumin microspheres in diabetes. Proc. AP. Acad. Sci., 11: 180-187.
  67. Jithan, A., 2007. In the era of nanotechnology: Trends in new drug discovery (Part II). Pharma. Buzz, 2: 19-26.
  68. Jithan, A., 2007. In the era of nanotechnology: Are drug delivery systems dawning a new dress (Part I). Pharma. Buzz, 2: 23-30.
  69. Jithan, A., 2007. In the era of nanotechnology: Applications of peptides and proteins as novel therapeutics (Part III). Pharma. Buzz, 2: 42-48.
  70. Bonepally, C.R., S.R. Challa, N.R.Yellu, M. Akkaledevi and J.V. Aukunuru, 2007. Preparation and characterization of piperine multilamellar vesicular liposomes intended to test anticonvulsant activity in the rats. Indian Drugs, 44: 458-465.
  71. Aukunuru, J., C. Bonepally and V. Guduri, 2007. Preparation, characterization and optimization of ibuprofen ointment intended for topical and systemic delivery. Trop. J. Pharm. Res., 6: 855-860.
    Direct Link  |  
  72. Jithan, A., A. Sridhar, B.C. Reddy and V.M. Reddy, 2007. Multiple regression analysis in optimizing formulation parameters of catechin-soya lecithin multilamellar vesicular liposomes. Indian Drugs, 44: 712-715.
  73. Aukunuru, J.V., C.R. Bonepally, K. Bommineni and M.R. Vanga, 2006. Prediction, optimization and development of piperine in soya-lecithin multilamellar vesicles using SAS and statistica neural network. Proc. A. P. Acad. Sci., 10: 207-214.
  74. Aukunuru, J.V., S.P. Ayalasomayajula and U.B. Kompella, 2003. Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells. J. Pharm. Pharmacol., 55: 1199-1206.
    CrossRef  |  PubMed  |  Direct Link  |  
  75. Aukunuru, J.V., G. Sunkara, S.P. Ayalasomayajula, J. DeRuiter, R.C. Clark and U.B. Kompella, 2002. A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications. Pharm. Res., 19: 278-285.
    CrossRef  |  PubMed  |  Direct Link  |  
  76. Aukunuru, J.V. and U.B. Kompella, 2002. In vitro delivery of nano- and micro-particles to human retinal pigment epithelial (ARPE-19) cells. Drug Del. Technol., 2: 50-57.
    Direct Link  |  
  77. Aukunuru, J.V., G. Sunkara, N. Bandi and U.B. Kompella, 2001. Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor. Pharm. Res., 18: 565-572.
    CrossRef  |  PubMed  |  Direct Link  |  
  78. Aukunuru, J.V., U.B. Kompella and G.V. Betageri, 2000. Simultaneous high performance liquid chromatographic analysis of acetaminophen, salicylamide, phenyltoloxamine, and related products. J. Liquid Chromatogr. Relat. Technol., 23: 565-578.
    CrossRef  |  Direct Link  |  
  79. Kompella, U.B., J.V. Aukunuru and G.V. Betageri, 1999. Effect of neutral liposomes on corneal and conjunctival transport of didanosine. Drug Delivery, 6: 9-14.
    Direct Link  |  
  80. Aukunuru, J.V. and U.B. Kompella, 1999. Recent advances in particulate and implant drug delivery systems. Invest. Drugs Weekly Highlights, 49: 58-61.
  81. Kompella, U.B., A.K. Katragadda, J.V. Aukunuru and G.V. Betageri, 1998. Effect of liposomal charge on stavudine transport across rabbit cornea and conjunctiva. Pharm. Pharmacol. Commun., 4: 339-343.
    CrossRef  |  Direct Link  |  

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