Dr. Aukunuru Venkata Jithan

Dr. Aukunuru Venkata Jithan

Head of Department
Omega College Of Pharmacy, India


Highest Degree
Ph.D. in Pharmaceutical Sciences from University of Nebraska Medical Center, Omaha, USA

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Area of Interest:

Biomedical Sciences
100%
Pharmaceutical Sciences
62%
Pharmacology and Toxicology
90%
Pharmacokinetics
75%
Drug Absorption
55%

Selected Publications

  1. Reddy, B.C.S., K. Bommineni and J. Aukunuru, 2019. Parenteral administered sustained release piperine microspheres intended to treat liver fibrosis. Int. J. Pharm. Sci. Res., 10: 1935-1943.

  2. Tadakapally, R., M. Habibuddin and J. Aukunuru, 2018. Preparation and characterization of PEG-Albumin-Paclitaxel (PAP)nanoparticles intended to treat breast cancer. Int. J. Chem. Tech. Res., 11: 143-145.

  3. Ghule, P., R. Gilhotra, A. Jithan, S. Bairagi and A. Aher, 2018. Amorphous solid dispersion: a promising technique for improving oral bioavailability of poorly water-soluble drugs-review. SA Pharm. J., 85: 50-56.
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  4. Devara, R., M. Habibuddin, K. Thadkala and J. Aukunuru, 2018. Preparation and evaluation of controlled release parenteral nanosuspensions of anastrazole. Int. J. Pharm. Tech. Res., 11: 96-107.
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  5. Devara, R., M. Habibuddin and J. Aukunuru, 2018. Enhancement of dissolution rate of poorly soluble itraconazole by nanosuspension technology: Its preparation and evaluation studies. Asian J. Pharm. Clin. Res., 11: 414-421.

  6. Das, S., S. Das, D. Pattanayak, C. Hossain, A.V. Jithan, 2018. Formulation and characterization of paracetamol co-crystals for enhanced bioavailability. J. Pharm. Drug Deliv. Res., Vol. 7. .
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  7. Aukunuru, J. and C. Bonepally, 2018. Optimization of encapsulation efficiency of piperine in soya-lecithin multilamellar vesicles. Int. J. Chem. Tech. Res., 10: 723-729.
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  8. Nallaguntla, L., Y.I. Muzib, J. Aukunuru and U. Balekari, 2017. Novel nanoparticles for the oral delivery of low molecular weight heparin: In vitro and in vivo assessment. Asian J. Pharmaceut. Clin. Res., 10: 254-261.
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  9. Thadkala, K., M.P. Reddy, J. Aukunuru and C. Sailu, 2017. Preparation and characterization of sustained release ranolazine microcapsules by W/O emulsification-solvent evaporation technique. Int. J. Chem. Tech. Res., 10: 1182-1184.
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  10. Thadakapally, R., A. Aafreen, J. Aukunuru, M. Habibuddin and S. Jogala, 2016. Preparation and characterization of PEG-albumin-curcumin nanoparticles intended to treat breast cancer. Indian J. Pharmaceut. Sci., 78: 65-72.
    PubMed  |  

  11. Lavanya, N., Y.I. Muzib, J. Aukunuru and U. Balekari, 2016. Preparation and evaluation of a novel oral delivery system for low molecular weight heparin. Int. J. Pharmaceut. Invest., 6: 148-157.
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  12. Jogala, S., S.S. Rachamalla and J. Aukunuru, 2016. Development of PEG-PLGA based intravenous Low Molecular Weight Heparin (LMWH) nanoparticles intended to treat venous thrombosis. Curr. Drug Delivery, 13: 698-710.
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  13. Jogala, S., J. Aukunuru and K.M. Chinnala, 2016. Novel subcutaneous sustained release nanoparticles encapsulating Low Molecular Weight Heparin (LMWH): Preparation, characterization and evaluation. Int. J. Pharm. Pharmaceut. Sci., 8: 264-268.
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  14. Yerragunta, B., S. Jogala, K.M. Chinnala and J. Aukunuru, 2015. Development of a novel 3-month drug releasing risperidone microspheres. J. Pharm. BioAllied Sci., 7: 37-44.
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  15. Jogala, S., S. Rachamalla and J. Aukunuru, 2015. Development of subcutaneous sustained release nanoparticles encapsulating low molecular weight heparin. J. Adv. Pharmaceut. Technol. Res., 6: 58-64.
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  16. Devara, R.K., H.U.R. Mohammad, B. Rambabu, J. Aukunuru and M. Habibuddin, 2015. Preparation, optimization and evaluation of intravenous curcumin nanosuspensions intended to treat liver fibrosis. Turk. J. Pharmaceut. Sci., 12: 8-24.
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  17. Bhogam, B., S. Chigiri, S. Aukunuru and Shayeda, 2015. Preparation, characterization and evaluation of anti-inflammatory activity of dexamethasone topical liposomal gel formulation. Am. J. Pharm Tech Res., 5: 315-331.
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  18. Bandigari, V., K. Thadkala, R.K. Devara and J. Aukunuru, 2015. Preparation and evaluation of orodispersable tablets of carbamazepine using different superdisintegrating agents. Int. J. Pharm Tech Res., 7: 438-447.

  19. Thadkala, K., P.K. Nanam, B. Rambabu, C. Sailu and J. Aukunuru, 2014. Preparation and characterization of amorphous ezetimibe nanosuspensions intended for enhancement of oral bioavailability. Int. J. Pharmaceut. Invest., 4: 131-137.
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  20. Tadudari, A., K. Thadkala, J. Kota and J. Aukunuru, 2014. Formulation, characterisation and evaluation of sustained release microcapsules of gemifloxacin. Int. J. PharmTech Res., 6: 1170-1179.

  21. Sappidi, S., K. Thadkala, J. Kota and J. Aukunuru, 2014. Preparation and characterization of ethyl cellulose microspheres encapsulating metformin hydrochloride and glipizide. Der Pharma Lettre, 6: 213-226.
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  22. Raju, A., A.J. Reddy, J. Satheesh and A.V. Jithan, 2014. Preparation and characterisation of nevirapine oral nanosuspensions. Indian J. Pharmaceut. Sci., 76: 62-72.
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  23. Navitha, A., S. Jogala, C. Krishnamohan and J. Aukunuru, 2014. Development of novel risperidone implants using blends of polycaprolactones and in vitro in vivo correlation studies. J. Adv. Pharmaceut. Technol. Res., 5: 84-89.
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  24. Nanam, P.K., K. Thadkala, C. Sailu and J. Aukunuru, 2014. Investigation of various practical techniques to enhance dissolution of ezetimibe from oral tablets: A comparative study. J. Young Pharmacists, 6: 8-15.
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  25. Kemisetti, D.P., S. Manda, J. Aukunuru, K.M. Chinnala and N.K. Rapaka, 2014. Synthesis of prodrugs of mefenamic acid and their in vivo evaluation. Int. J. Pharm. Pharmaceut. Sci., 6: 437-442.
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  26. Kemisetti, D., S. Manda, S.R. Satla, J. Aukunuru and N.K. Rapaka, 2014. Preparation of aceclofenac prodrugs, in vitro and in vivo evaluation. Int. J. Pharma Bio. Sci., 5: 239-253.
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  27. Kemisetti, D., S. Manda, N.K. Rapaka and A.V. Jithan, 2014. Synthesis of nimesulide conjugates, in vitro and in vivo evaluation. Der. Pharm. Chemica, 6: 317-329.
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  28. Kemisetti, D., S. Manda, J. Aukunuru and N.K. Rapaka, 2014. Polymeric prodrugs of diclofenac and in vivo evaluation. Int. J. Chem. Tech. Res., 6: 2637-2644.

  29. Shiny, J., T. Ramchander, P. Goverdhan, M. Habibuddin and J.V. Aukunuru, 2013. Development and evaluation of a novel biodegradable sustained release microsphere formulation of paclitaxel intended to treat breast cancer. Int. J. Pharmaceut. Invest., 3: 119-125.
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  30. Elthuri, I., C. Bonepally, S. Kokkula, R. Thadkapally and J. Aukunuru, 2013. Preparation and optimization of kupffer cell targeted catechin loaded spherical particles. Turk. J. Pharmaceut. Sci., 10: 35-47.
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  31. Bonepally, C.R., S.J. Gandey, K. Bommineni, K.M. Gottumukkala and J. Aukunuru, 2013. Preparation, characterisation and in vivo evaluation of silybin nanoparticles for the treatment of liver fibrosis. Trop. J. Pharmaceut. Res., 12: 1-6.
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  32. Bonepally, C.R., J. Aukunuru and K.M. Gottumukkala, 2013. Parenteral sustained release silybin microparticles intended for treatment of liver fibrosis. Int. J. Pharm. Biol. Sci., 3: 8-16.

  33. Path, S., P. Dara, S.K. Yamsani, R. Thadkapally and J. Aukunuru, 2012. Development and evaluation of oral elementary osmotic pump tablets for ropinirole hydrochloride. Indian Drugs, 49: 23-30.

  34. Madhavi, M., K. Madhavi and A.V. Jithan, 2012. Preparation and in vitro in vivo characterization of curcumin microspheres intended to treat colon cancer. J. Pharm. BioAllied Sci., 4: 164-171.
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  35. Setty, C.M., M. Radhika, V.R.M. Gupta, M.V.R. Reddy and A.V. Jithan, 2011. Effect of tablet processing and formulation factors on disintegration and dissolution of aceclofenac tablets. Int. J. Pharmaceut. Sci. Nanotechnol., 3: 1240-1251.
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  36. Koppisetti, V.S. and J. Aukunuru, 2011. Physicochemical stability of NNDBDC-a complete synthetic derivative of curcumin. J. Pharm. Res., 1: 761-762.
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  37. Konatham, S., B. Reddy and A. Jithan, 2011. Enhanced liver delivery and sustained release of curcumin with drug loaded nanoparticles after intravenous administration in rats. Asian J. Pharmaceut. Res. Health Care, 3: 99-108.
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  38. Jithan, A.V., K. Madhavi, M. Madhavi and K. Prabhakar, 2011. Preparation and characterization of albumin nanoparticles encapsulating curcumin intended for the treatment of breast cancer. Int. J. Pharmaceut. Invest., 1: 119-125.
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  39. Aukunuru, J., P. Tyagi, C. Durairaj and U.B. Kompella, 2011. Drug Suspension Development for the Back of the Eye. In: Drug Product Development for the Back of the Eye, Kompella, U. and H. Edelhauser (Eds.)., Springer Publications, New York, ISBN: 978-1-4419-9919-1, pp: 449-468.

  40. Anampally, S., S.K. Mankala, P.K. Gogu and J. Aukunur, 2011. Development of ropinirole (free base) transdermal patch using blends of hydroxypropyl methylcellulose/eudragits and it's in vitro/in vivo characterization. Asian J. Pharmaceut. Res. Health Care, 3: 89-98.
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  41. Swathi, M., J. Aukunuru and Y.M. Rao, 2010. Formulation, characterization and evaluation of granisetron buccal patches. J. Pharm. Chem., 4: 109-113.
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  42. Swapna, N. and A.V. Jithan, 2010. Preparation, characterization in vivo evaluation of parenteral sustained release microsphere formulation of zopiclone. J. Young Pharmacists, 2: 223-228.
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  43. Sankavarapu, V. and J. Aukunuru, 2010. Development and evaluation of zero order sustained release matrix type transdermal films of ibuprofen. J. Global Pharma Technol., 2: 51-58.

  44. Konatham, S., P. Kumar and J. Aukunuru, 2010. Synthesis and screening of antidiabetic activity of some novel curcumin analogues. Int. J. Pharma Bio Sci., 1: 1-12.
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  45. Konatham, S., H.K. Nyathani, C.R. Bonepally, P.K. Yannamaneni and J. Aukunuru, 2010. Liposomal delivery of curcumin to liver. Turk. J. Pharmaceut. Sci., 7: 89-98.
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  46. Jithan, A.V. and M. Swathi, 2010. Development of topical diclofenac sodium liposomal gel for better anti-inflammatory activity. Int. J. Pharm. Sci. Nanotech., 3: 986-993.

  47. Gogu, P.K. and A.V. Jithan, 2010. Preparation and in vitro/in vivo characterization of spray dried microsphere formulation encapsulating 4-chlorocurcumin. Indian J. Pharmaceut. Sci., 72: 346-352.
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  48. Garipelli, N., B.M. Reddy and A.V. Jithan, 2010. Synthesis and evaluation of clozapine and its related compounds. Int. J. Pharm. Sci. Nanotechnol., 2: 762-767.
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  49. Gaddam, N. and J. Aukunuru, 2010. Systemic delivery of diclofenac sodium after topical application of gels incorporated with drug-loaded Solid Lipid Nanoparticles (SLN). Asian J. Pharmaceut. Res. Health Care, 2: 177-187.
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  50. Aukunuru, J. and V. Sankavarapu, 2010. Pharmacokinetics and in vitro and in vivo correlation of NN-dimethylaminocurcumin (NNDMAC) loaded polycaprolactone microspheres in rats. Curr. Trends Biotechnol. Pharm., 4: 578-588.
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  51. Anuradha, C.A. and J. Aukunuru, 2010. Preparation, characterisation and in vivo evaluation of Bis-Demethoxy Curcumin Analogue (BDMCA) nanoparticles. Trop. J. Pharmaceut. Res., 9: 51-58.
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  52. Anampelli, S. and J. Aukunuru, 2010. Development of ganisetron transdermal films: In vitro and ex vivo characterization. Indian Drugs, 47: 21-28.

  53. Shankeshi, J. and J. Aukunuru, 2009. Preparation, characterization and evaluation of antidiabetic activity of a liposomal formulation encapsulating curcumin, an ayurvedic natural product. Pharmacist, 3: 105-125.

  54. Sankavarapu, V. and J. Aukunuru, 2009. Preparation, characterization and evaluation of hepatoprotective activity of NNDMAC biodegradable parenteral sustained release microspheres. J. Pharmaceut. Res. Health Care, 1: 240-259.
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  55. Garipelli, N., R.B. Sunoj, B.M. Reddy, A.V. Jithan and C. Runja, 2009. Quantification of intramolecular hydrogen bond in neurotransmitter dopamine. Int. J. Pharm. Sci. Nanotechnol., 2: 671-674.
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  56. Aukunuru, J., S. Joginapally, N. Gaddam, M. Burra and C.R. Bonepally, 2009. Preparation, characterization and evaluation of hepatoprotective activity of an intravenous liposomal formulation of Bis-Demethoxy Curcumin Analogue (BDMCA). Int. J. Drug Dev. Res., 1: 37-46.
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  57. Aukunuru, J., K.M. Chinnala and V. Guduri, 2009. Development of a novel transdermal ibuprofen ointment. Curr. Trends Biotechnol. Pharmacy, 3: 97-104.
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  58. Aukunuru, J., K. Eedula, V. Pasham, V. Katla and K.S. Reddy, 2009. Synthesis of novel piperonal derivatives and evaluation of their anticonvulsant activity using a nanoparticular formulation. Int. J. Pharm. Sci. Nanotechnol., 2: 435-442.
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  59. Aukunuru, J. and C. Runja, 2009. Synthesis and evaluation of antidepressant activity of some curcumin-like compounds. Pharm. Commun., 2: 38-41.

  60. Viswanath, G., A. Jithan and V.M. Reddy, 2008. Development of new delivery strategies to increase bioavailability of curcumin. Int. J. Pharm. Sci. Nanotechnol., 1: 335-340.
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  61. Sridhar, A., A.V. Jithan and V.M. Reddy, 2008. Comparative pharmacokinetics of free and liposome-encapsulated catechin after intravenous and intraperitoneal administration. Int. J. Pharm. Sci. Nanotechnol., 1: 152-159.
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  62. Jithan, A.V., C.K. Mohan and M.V. Devi, 2008. Development and evaluation of a chloramphenicol hypertonic ophthalmic solution. Indian J. Pharm. Sci., 70: 66-70.
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  63. Ganji, S., K.M. Chinnala and J. Aukunuru, 2008. Preparation, excipient properties and pharmacological activities of okra mucilage. Pharmacog. Mag., 4: 73-77.

  64. Ganji, S. and J. Aukunuru, 2008. Formulation, excipient properties and pharmacological activities of catechin liposomes. Pharmacog. Magazine, 4: 121-126.
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  65. Chandrasekhar, R., Bonepally, J. Aukunuru, N.R. Yellu and M.R. Vanga, 2008. Fabrication and investigations on hepatoprotective activity of sustained release biodegradable piperine microspheres. Int. J. Pharm. Sci. Nanotechnol., 1: 87-96.
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  66. Shankeshi, J., J. Aukunuru and M.R. Vanga, 2007. Preclinical assessment of sustained release biodegradable curcumin microspheres in diabetes. Proc. AP. Acad. Sci., 11: 180-187.

  67. Jithan, A., 2007. In the era of nanotechnology: Trends in new drug discovery (Part II). Pharma. Buzz, 2: 19-26.

  68. Jithan, A., 2007. In the era of nanotechnology: Are drug delivery systems dawning a new dress (Part I). Pharma. Buzz, 2: 23-30.

  69. Jithan, A., 2007. In the era of nanotechnology: Applications of peptides and proteins as novel therapeutics (Part III). Pharma. Buzz, 2: 42-48.

  70. Bonepally, C.R., S.R. Challa, N.R.Yellu, M. Akkaledevi and J.V. Aukunuru, 2007. Preparation and characterization of piperine multilamellar vesicular liposomes intended to test anticonvulsant activity in the rats. Indian Drugs, 44: 458-465.

  71. Aukunuru, J., C. Bonepally and V. Guduri, 2007. Preparation, characterization and optimization of ibuprofen ointment intended for topical and systemic delivery. Trop. J. Pharm. Res., 6: 855-860.
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  72. Jithan, A., A. Sridhar, B.C. Reddy and V.M. Reddy, 2007. Multiple regression analysis in optimizing formulation parameters of catechin-soya lecithin multilamellar vesicular liposomes. Indian Drugs, 44: 712-715.

  73. Aukunuru, J.V., C.R. Bonepally, K. Bommineni and M.R. Vanga, 2006. Prediction, optimization and development of piperine in soya-lecithin multilamellar vesicles using SAS and statistica neural network. Proc. A. P. Acad. Sci., 10: 207-214.

  74. Aukunuru, J.V., S.P. Ayalasomayajula and U.B. Kompella, 2003. Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells. J. Pharm. Pharmacol., 55: 1199-1206.
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  75. Aukunuru, J.V., G. Sunkara, S.P. Ayalasomayajula, J. DeRuiter, R.C. Clark and U.B. Kompella, 2002. A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications. Pharm. Res., 19: 278-285.
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  76. Aukunuru, J.V. and U.B. Kompella, 2002. In vitro delivery of nano- and micro-particles to human retinal pigment epithelial (ARPE-19) cells. Drug Del. Technol., 2: 50-57.
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  77. Aukunuru, J.V., G. Sunkara, N. Bandi and U.B. Kompella, 2001. Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor. Pharm. Res., 18: 565-572.
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  78. Aukunuru, J.V., U.B. Kompella and G.V. Betageri, 2000. Simultaneous high performance liquid chromatographic analysis of acetaminophen, salicylamide, phenyltoloxamine, and related products. J. Liquid Chromatogr. Relat. Technol., 23: 565-578.
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  79. Kompella, U.B., J.V. Aukunuru and G.V. Betageri, 1999. Effect of neutral liposomes on corneal and conjunctival transport of didanosine. Drug Delivery, 6: 9-14.
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  80. Aukunuru, J.V. and U.B. Kompella, 1999. Recent advances in particulate and implant drug delivery systems. Invest. Drugs Weekly Highlights, 49: 58-61.

  81. Kompella, U.B., A.K. Katragadda, J.V. Aukunuru and G.V. Betageri, 1998. Effect of liposomal charge on stavudine transport across rabbit cornea and conjunctiva. Pharm. Pharmacol. Commun., 4: 339-343.
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