Prof. Dr. Amani Shafeek Awaad
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Prof. Dr. Amani Shafeek Awaad

Professor
Prince Sattam Bin Abdulaziz University, Saudi Arabia

Highest Degree
Ph.D. in Pharmaceutical Sciences from Cairo University, Egypt

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Area of Interest:

Pharmacology and Toxicology
100%
Pharmaceutical Sciences
62%
Biological Activities
90%
Pharmacognosy
75%
Natural Product
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Ibrahim, N.H., A.S. Awaad, R.A. Alnafisah, S.I. Alqasoumi, R.M. El-Meligy and A.Z. Mahmoud, 2018. In-vitro activity of Desmostachya bipinnata (L.) Stapf successive extracts against Helicobacter pylori clinical isolates. Saudi Pharm. J., 26: 535-540.
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  2. Awaad, A.S. and E.A.A. Alothman, 2018. Antiulcer and anti-ulcerative colitis activities of Haplophyllum tuberculatum (Forsskal). Int. J. Pharmacol., 14: 31-38.
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  3. Awaad, A.A., R.M. El‐Meligy, G.M. Zain, A.A. Safhi and N.A. Al Qurain et al., 2018. Experimental and clinical antihypertensive activity of Matricaria chamomilla extracts and their angiotensin‐converting enzyme inhibitory activity. Phytother. Res., 32: 1564-1573.
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  4. Awaad, A.A., H.F. Alkanhal, R.M. El-Meligy, G.M. Zain, V.D.S. Adri, D.A. Hassan and S.I. Alqasoumi, 2018. Anti-ulcerative colitis activity of Calotropis procera Linn. Saudi Pharm. J., 26: 75-78.
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  5. Alothman, E.A., A.S. Awaad, N.A. Al-Qurayn, H.F. Al-Kanhal and R.M. El-Meligy et al., 2018. Anticancer effect of Cenchrus ciliaris L. Saudi Pharm. J., 26: 952-955.
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  6. Alothman, E.A., A.S. Awaad, A.A. Safhi, S.S. Almoqren and R.M. El-Meligy et al., 2018. Evaluation of anti-ulcer and ulcerative colitis of Sonchus oleraceus L. Saudi Pharm. J., 26: 956-959.
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  7. Alasmary, F.A., A.S. Awaad, M. Kamal, S.I. Alqasoumi and M.E. Zain, 2018. Antitumor activity of extract and isolated compounds from Drechslera rostrata and Eurotium tonophilum. Saudi Pharm. J., 26: 279-285.
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  8. Alasmary, F.A., A.S. Awaad, A.M. Alafeefy, R.M. El-Meligy and S.I. Alqasoumi, 2018. Novel quinazoline and acetamide derivatives as safe anti-ulcerogenic agent and anti-ulcerative colitis activity. Saudi Pharm. J., 26: 138-143.
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  9. Al-Saleem, M.S., A.S. Awaad, M.R. Alothman and S.I. Alqasoumi, 2018. Phytochemical standardization and biological activities of certain desert plants growing in Saudi Arabia. Saudi Pharmaceut. J., 26: 198-204.
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  10. Al-Hazmi, G.H., A.S. Awaad, M.R. Alothman and S.I. Alqasoumi, 2018. Anticandidal activity of the extract and compounds isolated from Cyperus conglomertus Rottb. Saudi Pharm. J., 26: 891-895.
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  11. Al-Enazi, N.M., A.S. Awaad, S.I. Alqasoumi and M.F. Alwethairi, 2018. Biological activities of the red algae Galaxaura rugosa and Liagora hawaiiana butters. Saudi Pharm. J., 26: 25-32.
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  12. Al-Enazi, N.M., A.S. Awaad, M.R. Al-Othman, N.K. Al-Anazi and S.I. Alqasoumi, 2018. Isolation, identification and anti-candidal activity of filamentous fungi from Saudi Arabia soil. Saudi Pharm. J., 26: 253-257.
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  13. Al-Enazi, N.M., A.S. Awaad, M.E. Zain and S.I. Alqasoumi, 2018. Antimicrobial, antioxidant and anticancer activities of Laurencia catarinensis, Laurencia majuscule and Padina pavonica extracts. Saudi Pharm. J., 26: 44-52.
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  14. El-Meligy, R.M., A.S. Awaad, G.A. Soliman, S.A. Kenawy and S.I. Alqasoumi, 2017. Prophylactic and curative anti-ulcerogenic activity and the possible mechanisms of action of some desert plants. Saudi Pharm. J., 25: 387-396.
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  15. Awad, E. and A. Awaad, 2017. Role of medicinal plants on growth performance and immune status in fish. Fish Shellfish Immunol., 67: 40-54.
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  16. Awaad, S.A., M.R. Alothman, Y.M. Zain, S.I. Alqasoumi and E.A. Alothman, 2017. Quantitative and qualitative analysis for standardization of Euphorbia cuneata Vahl. Saudi Pharmaceut. J., 25: 1175-1178.
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  17. Awaad, A.S., N.K. Al-Aonazi, M.R. Al-Othman, M.E. Zain, R.M. El-Meligy and N. El-Sayed, 2017. Anticandidal activity of extracts and a novel compound, amnomopin, isolated from Petriella setifera. Phytother. Res., 31: 1504-1508.
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  18. Awaad, A.S., M.R. Alothman, Y.M. Zain, G.M. Zain, S.I. Alqasoumi and D.A. Hassan, 2017. Comparative nutritional value and antimicrobial activities between three Euphorbia species growing in Saudi Arabia. Saudi Pharmaceut. J., 25: 1226-1230.
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  19. Awaad, A.S., H.A. Al-Mudhayyif, M.R. Al-Othman, M.E. Zain and R.M. El-Meligy, 2017. Amhezole, a novel fungal secondary metabolite from Aspergillus terreus for treatment of microbial mouth infection. Phytother. Res., 31: 395-402.
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  20. Awaad, A.S., A.M. Alafeefy, F.A.S. Alasmary, R.M. El-Meligy, M.E. Zain and S.I. Alqasoumi, 2017. Novel essential amino acid-sulfanilamide hybrid as safe anti-ulcerogenic agent with anti-Helicobacter pylori activity. Saudi Pharmaceut. J., 25: 967-971.
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  21. Awaad, A.S., A.M. Alafeefy, F.A.S. Alasmary, R.M. El-Meligy and S.I. Alqasoumi, 2017. Anti-ulcerogenic and anti-Ulcerative Colitis (UC) activities of seven amines derivatives. Saudi Pharmaceut. J., 25: 1125-1129.
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  22. Awaad, A.A., H.F. Alkanhal, R.M. El-Meligy, G.M. Zain, V.D.S. Adri, D.A. Hassan and S.I. Alqasoumi, 2017. Anti-ulcerative colitis activity of Calotropis procera Linn. Saudi Pharmaceut. J., (In Press). 10.1016/j.jsps.2017.10.010.
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  23. Alasmary, F.A., A.S. Awaad, M. Kamal, S.I. Alqasoumi and M.E. Zain, 2017. Antitumor activity of extract and isolated compounds from Drechslera rostrata and Eurotium tonophilum. Saudi Pharmaceut. J., (In Press). 10.1016/j.jsps.2017.11.011.
    CrossRef  |  Direct Link  |  
  24. Alasmary, F.A., A.S. Awaad, A.M. Alafeefy, R.M. El-Meligy and S.I. Alqasoumi, 2017. Novel quinazoline and acetamide derivatives as safe anti-ulcerogenic agent and anti-ulcerative colitis activity. Saudi Pharmaceut. J., (In Press). 10.1016/j.jsps.2017.09.011.
    CrossRef  |  Direct Link  |  
  25. Al-Saleem, M.S., A.S. Awaad, M.R. Alothman and S.I. Alqasoumi, 2017. Phytochemical standardization and biological activities of certain desert plants growing in Saudi Arabia. Saudi Pharmaceut. J., (In Press). 10.1016/j.jsps.2017.12.011.
    CrossRef  |  Direct Link  |  
  26. Al-Enazi, N.M., A.S. Awaad, M.R. Al-Othman, N.K. Al-Anazi and S.I. Alqasoumi, 2017. Isolation, identification and anti-candidal activity of filamentous fungi from Saudi Arabia soil. Saudi Pharmaceut. J., (In Press). 10.1016/j.jsps.2017.12.003.
    CrossRef  |  Direct Link  |  
  27. Al-Enazi, N.M., A.S. Awaad, M.E. Zain and S.I. Alqasoumi, 2017. Antimicrobial, antioxidant and anticancer activities of Laurencia catarinensis, Laurencia majuscula and Padina pavonica extracts. Saudi Pharmaceut. J., (In Press). 10.1016/j.jsps.2017.11.001.
    CrossRef  |  Direct Link  |  
  28. Awaad, A.S., S.M. Alotiby, R.M. El-Meligy, M.S. Marzouk, S.I. Alqasoumi, A.E.R.M. Donia and N.H. El-Sayed, 2016. Novel anti-ulcerogenic effects of total extract and isolated compounds from Cakile arabica. Int. J. Pharmacol., 12: 541-548.
    CrossRef  |  
  29. Awaad, A.S., M. Abdalqawi, S.A. Kenawi, M.R. Alothman, S. Rehab and M. Zain, 2016. Pharmacological activities for the extract and isolated compounds of Euphorbia cuneata Vhl. Int. J. Biol. Pharm. Allied Sci., 5: 319-331.
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  30. Awaad, A.S., A. Al-Refaie, R. El-Meligy, M. Zain, H. Soliman, M.S. Marzoke and N. El-Sayed, 2016. Novel compounds with new anti-ulcergenic activity from Convolvulus pilosellifolius using bio-guided fractionation. Phytother. Res., 30: 2060-2064.
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  31. El-Meligy, R.M., A.S. Awaad, G.A. Soliman, A.B. Bacha, A.M. Alafeefy and S.A. Kenawy, 2015. Prophylactic and curative anti-ulcerative colitis activity and the possible mechanisms of action of some desert plants. J. Enzyme Inhibit. Med. Chem., 30: 250-258.
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  32. Awad, E., A.S. Awaad and M.A. Esteban, 2015. Effects of dihydroquercetin obtained from deodar (Cedrus deodara) on immune status of gilthead seabream (Sparus aurata L.). Fish Shellfish Immunol., 43: 43-50.
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  33. Awaad, A.S., R.M. El-Meligy, S.H. Al-Qahtani, H.E. Al-Duhailan and G.M. Zain, 2015. Aloe vera as a natural car thermal insulator. Int. J. Biol. Pharm. Allied Sci., 4: 6116-6123.
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  34. Awaad, A.S., A.A. Al-Rifai, R.M. El-Meligy, A.M. Alafeefy and M.E. Zain, 2015. New activities for isolated compounds from Convolvulus austro-aegyptiacus as anti-ulcerogenic, anti-Helicobacter pylori and their mimic synthesis using bio-guided fractionation. Phytother. Res., 29: 1311-1316.
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  35. Alasmary, F.A., A.M. Snelling, M.E. Zain, A.M. Alafeefy, A.S. Awaad and N. Karodia, 2015. Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents. Molecules, 20: 15206-15223.
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  36. Alafeefy, A.M., M.A. Bakht, M.A. Ganaie, M.N. Ansarie, N.N. El-Sayed and A.S. Awaad, 2015. Synthesis, analgesic, anti-inflammatory and anti-ulcerogenic activities of certain novel Schiff's bases as fenamate isosteres. Bioorg. Med. Chem. Lett., 25: 179-183.
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  37. Alafeefy, A.M., H.A. Abdel-Aziz, D. Vullo, A.M.S. Al-Tamimi and A.S. Awaad et al., 2015. Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-,[1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. J. Enzyme Inhibit. Med. Chem., 30: 52-56.
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  38. Alafeefy, A.M., A.S. Awaad, H.A. Abdel-Aziz, R.M. El-Meligy, M.E. Zain, M.R. Al-Outhman and A.B. Bacha, 2015. Synthesis and biological evaluation of certain 3-substituted benzylideneamino-2-(4-nitrophenyl) quinazolin-4(3H)-one derivatives. J. Enzyme Inhibit. Med. Chem., 30: 270-276.
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  39. Al-Rifai, A.A., A. Aqel, A. Awaad and Z.A. Al-Othman, 2015. Analysis of quercetin and kaempferol in an alcoholic extract of Convolvulus pilosellifolius using HPLC. Commun. Soil Sci. Plant Anal., 46: 1411-1418.
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  40. Zain, M.E., A.S. Awaad, M.R. Al-Othman, A.M. Alafeefy and R.M. El-Meligy, 2014. Biological activity of fungal secondary metabolites. Int. J. Chem. Applied Biol. Sci., 1: 14-22.
  41. Zain, M.E., A.S. Awaad, M.R. Al Othman and S.K. Al-Dosary, 2014. Antibacterial, antifungal activity and phytochemical analysis of some desert plants against human pathogenic bacteria and fungi. Life Sci. J., 11: 343-349.
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  42. El-Meligy, R.M., A.S. Awaad, M.E. Zain, A.M. Alafeefy and S.A. Kenawy, 2014. Anti-inflammatory and antinociceptive activities of extracts and compounds isolated from Solenostemma arghel (Del.) Hayne. Int. J. Chem. Applied Biol. Sci., 1: 1-8.
  43. Awaad, A.S., T.A. Alhamed, D.J. Maitland, G.A. Soliman and N.A. Al-Jaber et al., 2014. Evaluation of the antimicrobial activity, sub-chronic toxicity and wound healing effect of Cunninghamella elegans extract and its isolated compounds. Life Sci. J., 11: 261-268.
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  44. Awaad, A.S., M.E. Zain, M.R. Al Othman and S.K. Al-Dosary, 2014. Phytochemical analysis and antimicrobial activity of medicinal plants against pathogenic microorganisms. Life Sci. J., 11: 350-354.
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  45. Awaad, A.S., H.M. Al-Zaylaee, S.I. Alqasoumi, M.E. Zain and E.M. Aloyan et al., 2014. Anti-leishmanial activities of extracts and isolated compounds from Drechslera rostrata and Eurotium tonpholium. Phytother. Res., 28: 774-780.
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  46. Awaad, A.S., A.A. Al-Rifai, R.M. El-Meligy, A.M. Alafeefy and S.I. Alqasoumi, 2014. Antiulcerogenic activity of Convolvulus species. Austin Chromatogr., Vol. 1, No. 4. .
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  47. Alafeefy, A.M., S.I. Alqasoumi, S.G. Abdel Hamid, K.E.H. El-Tahir, M. Mohamed, M.E. Zain and A.S. Awaad, 2014. Synthesis and hypoglycemic activity of some new theophylline derivatives. J. Enzyme Inhibit. Med. Chem., 29: 443-448.
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  48. El-Meligy, R.M., A.S. Awaad, M.E. Zain and A.M. Alafeefy, 2013. Evaluation of selected desert plants as anti-ulcerogenic natural products. Aust. J. Basic Applied Sci., 7: 431-436.
    Direct Link  |  
  49. Donia, A.E.R.M., G.A. Soliman, A.M. Zaghloul, S.I. Alqasoumi, A.S. Awaad, A.M. Radwan and O.A. Basodan, 2013. Chemical constituents and protective effect of Ficus ingens (Miq.) Miq. on carbon tetrachloride-induced acute liver damage in male Wistar albino rats. J. Saudi Chem. Soc., 17: 125-133.
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  50. Awaad, A.S., R.M. El-Meligy, N.A. Al-Jaber, H.S. Al-Muteeri and M.E. Zain et al., 2013. Anti-ulcerative colitis activity of compounds from Euphorbia granuleta Forssk. Phytother. Res., 27: 1729-1734.
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  51. Awaad, A.S., R.M. El-Meligy and G.A. Soliman, 2013. Natural products in treatment of ulcerative colitis and peptic ulcer. J. Saudi Chem. Soc., 17: 101-124.
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  52. Awaad, A.S., N.A. Al-Jaber, J.E. Moses, R.M. El-Meligy and M.E. Zain, 2013. Antiulcerogenic activities of the extracts and isolated flavonoids of Euphorbia cuneata Vahl. Phytother. Res., 27: 126-130.
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  53. Alafeefy, A.M., S. Isik, N.A. Al-Jaber, D. Vullo and H.A. Abdel-Aziz et al., 2013. Carbonic anhydrase inhibitors. Benzenesulfonamides incorporating cyanoacrylamide moieties strongly inhibit Saccharomyces cerevisiae β-carbonic anhydrase. Bioorg. Med. Chem. Lett., 23: 3570-3575.
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  54. Zain, M.E., A.S. Awaad, M.R. Al-Outhman and R.M. El-Meligy, 2012. Antimicrobial activities of Saudi Arabian desert plants. Phytopharmacology, 2: 106-113.
  55. Soliman, G.A., A.E.R.M. Donia, A.S. Awaad, S.I. Alqasoumi and H. Yusufoglu, 2012. Effect of Emex spinosa, Leptadenia pyrotechnica, Haloxylon salicornicum and Ochradenus baccatus extracts on the reproductive organs of adult male rats. Pharmaceut. Biol., 50: 105-112.
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  56. Awaad, A.S., N.A. Al-Jaber, G.A. Soliman, M.R. Al-Outhman, M.E. Zain, J.E. Moses and R.M. El-Meligy, 2012. New biological activities of Casimiroa edulis leaf extract and isolated compounds. Phytother. Res., 26: 452-457.
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  57. Awaad, A.S., G.A. Soliman, D.F. El-Sayed, O.D. El-Gindi and S.I. Alqasoumi, 2012. Hepatoprotective activity of Cyperus alternifolius on carbon tetrachloride-induced hepatotoxicity in rats. Pharmaceut. Biol., 50: 155-161.
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  58. Awaad, A.S., D.J. Maitland, A.E.R.M. Donia, S.I. Alqasoumi and G.A. Soliman, 2012. Novel flavonoids with antioxidant activity from a Chenopodiaceous plant. Pharmaceut. Biol., 50: 99-104.
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  59. Awaad, A.S., A.J.A. Nabilah and M.E. Zain, 2012. New antifungal compounds from Aspergillus terreus isolated from desert soil. Phytother. Res., 26: 1872-1877.
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  60. Alqasoumi, S.I., G.A.E.H. Soliman, A.S. Awaad and A.E.R.M. Donia, 2012. Anti-inflammatory activity, safety and protective effects of Leptadenia pyrotechnica, Haloxylon salicornicum and Ochradenus baccatus in ulcerative colitis. Phytopharmacology, 2: 58-71.
    Direct Link  |  
  61. Spiteri, C., D.J. Ritson, A. Awaad and J.E. Moses, 2011. Silver mediated one-step synthesis of oxazoles from α-haloketones. J. Saudi Chem. Soc., 15: 375-378.
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  62. Sharma, P., K.J. Powell, J. Burnley, A.S. Awaad and J.E. Moses, 2011. Total synthesis of polypropionate-derived γ-pyrone natural products. Synthesis, 18: 2865-2892.
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  63. Donia, A.E.R.M., S.I. Alqasoumi, A.S. Awaad and L. Cracker, 2011. Antioxidant activity of Covolvulus hystrix Vahl and its chemical constituents. Pak. J. Pharm. Sci., 24: 143-147.
    PubMed  |  Direct Link  |  
  64. Awaad, A.S., R.M. El-meligy, S.A. Qenawy, A.H. Atta and G.A. Soliman, 2011. Anti-inflammatory, antinociceptive and antipyretic effects of some desert plants. J. Saudi Chem. Soc., 15: 367-373.
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  65. Awaad, A.S., G.A. Soliman, M.R. Al-Outhman, I.F. Al-Shdoukhi and R.S. Al-Nafisah et al., 2011. The effect of four coffee types on normotensive rats and normal/hypertensive human volunteers. Phytother. Res., 25: 803-808.
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  66. Zain, M.E., A.S. Awaad, A.A. Razak, D.J. Maitland, N.E. Khamis and M.A. Sakhawy, 2009. Secondary metabolites of Aureobasidium pullulans isolated from Egyptian soil and their biological activity. J. Applied Sci. Res., 5: 1582-1591.
  67. Awaad, A.S., 2009. Flavonoids of Bidens bipinnata and their antioxidant activity. J. King Saud Univ., 21: 183-189.
  68. Amani, S.A., N.H. Mohamed, D.J. Maitland and G.A. Soliman, 2008. Anti-ulcerogenic activity of extract and some isolated flavonoids from Desmostachia bipinnata (L.) Stapf. Rec. Nat. Prod., 2: 76-82.
  69. Awaad, A.S., D.J. Maitland, A.M. Donia, AI. Hashem and G.A. Soliman, 2007. New antioxidant favonoids from Atriplex lentiformis (torr.) S. wats. RPMP Phytopharmacol. Therapeutic Values, 23: 47-59.
  70. Awaad, A.S., D.J. Maitland and S. Moneir, 2007. New alkaloids from Casimiroa edulis fruits and their pharmacological activity. Chem. Natural Compounds, 43: 576-580.
  71. El-Sayed, N.H., K.F. Amer, A.S. Awad, N.H.M. Hassan and T.J. Mabry, 2006. Bioactive chemical constituents from Convolvulus arvensis. Asian J. Chem., 18: 2826-2827.
  72. Awaad, A.S., N.H. El-Sayed, D.J. Maitland and T.J. Mabry, 2006. Phenolic antioxidants from Casimiroa edulis leaves. Pharmacu. Biol., 44: 258-262.
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  73. Awaad, A.S., D.J. Maitland and G.A. Soliman, 2006. Hepatoprotective activity of Schouwia thebica webb. Bioorganic Medic. Chem. letters, 16: 4624-4628.
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  74. Awaad, A.S., D. J. Maitland and G.A. Soliman, 2006. Antioxidant, and other Biological Activities of Sisymbrium erysimoides Dess., Fl. Egyptian J. Biomedical Sci., 21: 34-46.
  75. Awaad, A.S., 2006. Phenolic glycosides of Juncus actus L. and its Anti-eczematic activity. Che. Natural Compounds, 42: 152-155.
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  76. Amani, A.S.A., D.J. Maitland and G.A. Soliman, 2006. Antiulcerogenic activity of Alhagi maurorum. Pharmacut. Biol., 44: 292-296.
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  77. Awaad, A.S., A.M. Donia, A.I. Hashem, M.A. El-Shurbagy and G.A. Soliman, 2005. Phytochemical content and effect of Atriplex lentiformis (Torm.) S.wats. in animal nutrition. Bull. Fac. Pharm., 43: 169-174.
  78. EL-Sayed, N.H., A.S. Awaad and T.J. Mabry, 2004. Phytochemical studies and effect on urine volume of Glossostemon brugeiri Desf. constituents. Indian J. Exp. Biol., 42: 186-189.
  79. Awaad, A.S., N.H. Mohamed, N.H. El-Sayed, G.A. Soliman and T.J. Mabry, 2004. Flavonoids, carbohydrates and some pharmacological screening of Convolvulus arvensis. J. Desert Res. Centre, 54: 15-33.
  80. Awaad, A.S., N.H. Mohamed and F.A. Khadiega, 2004. Biological effect for alkaloids and coumarins of Convolvulus arvensis. J. Desert Res. Centre, 54: 315-326.
  81. Awaad, A.S., 2004. Coumarins of Conyza linofolia (Will) Takholm, and their anticoagulant activity. Bull. Fac. Pharm., Cairo Univ., 42: 153-156.
  82. Awaad, A.S., N.M. Sokkar and G.M. Soliman, 2001. Flavonoids and coumarins from Hammada elegans (bunge) botsch and their biological activity. Bull. Fac. Pharm. Cairo Univ., 39: 121-127.
  83. Awaad, A.S., N.M. Sokkar and H.A. Khafaga, 2000. Pharmacognostical studies and biological activity for Vernonia galamensis sub-species galamensis var. petitiana (A. rich) M. Gilbert. Bull. Fac. Pharm. Cairo Univ., 38: 107-113.
  84. Awaad, A.S., 2000. Phytochemical investigation and biological activities of Cynancum acutum growing in Egypt. Bull. Fac. Pharm., Cairo Univ., 38: 153-162.
  85. Aboutabl, E.A., N.M. Sokkar and A.S. Awaad, 2000. Phytochemical study of Otostegia fruticosa (Forssk.) and biological activity. Bull. Fac. Pharm. Cairo Univ., 38: 115-118.
  86. Awaad, A.S., K.F. Amer and N.H. Hassan, 1999. Phytochemical investigation, carbohydrate, protein, lipid contents and antimicrobial activity of Diplotaxis acres. Bull. Fac. Pharm. Cairo Univ., 37: 81-87.
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