Dr. Saeed  Mohammadi

Dr. Saeed Mohammadi

Assistant Professor
Golestan University of Medical Sciences, Iran


Highest Degree
Ph.D. in Molecular Medicine from Golestan University of Medical Sciences, Iran

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Biography

Saeed Mohammadi has completed his PhD at Golestan University of Medical Sciences Department of Molecular Medicine Gorgan, Golestan, Iran. He has completed his MSc in Medical Parasitology from Zahedan University of Medical Sciences, Iran. He is member of Iranian Society of Clinical Laboratory and Iranian Society of Medical Parasitology. His main area of interest focuses on Systemic Lupus Erythmatosous, Macrophages, Innate Immunity, Aryl Hydrocarbon, Receptor/Transcription Factor, PAHs, and Environmental Toxicants. He is Editor-in-Chief for Hakim Seyed Esmaeil Jorjani Journal of Research in Medical Sciences, Golestan University of Medical Sciences. He has worked in 7 research projects. He has 14 publications in journals contributed as author/co-author.

Area of Interest:

Biomedical Sciences
100%
Immunology
62%
Autoimmune Disorders
90%
Stem Cell Therapy
75%
Innate Immunity
55%

Selected Publications

  1. Shokoohifar, N., S. Ahmady-Asbchin, S. Besharat, F. Roudbari and S. Mohammadi et al., 2020. The impaired balance of CD4+/CD8+ ratio in patients with chronic Hepatitis B. Hepat. Mon., 10.5812/hepatmon.96799.
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  2. Shahryari, A., M.S. Jazi, S. Mohammadi, H.R. Nikoo, Z. Nazari et al., 2019. Development and clinical translation of approved gene therapy products for genetic disorders. Front. Genet., 10.3389/fgene.2019.00868.
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  3. Seyedhosseini, F.S., S. Mohammadi, M.Z. Ebrahimabad, B. Khodabakhshi, A. Abbasi and Y. Yazdani, 2019. Interleukin-6, Interleukin-17 and transforming growth factor-beta are overexpressed in newly diagnosed tuberculosis patients; potent biomarkers of mycobacterial infection. Arch. Clin. Infect. Dis., 10.5812/archcid.68417.
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  4. Sani, N.A., M. Hasani, A. Kianmehr, S. Mohammadi, M.S. Arabi and Y. Yazdani, 2019. Enhanced nuclear translocation and activation of aryl hydrocarbon receptor (AhR) in THP-1 monocytic cell line by a novel niosomal formulation of indole-3-carbinol. J. Liposome Res., 30: 117-125.
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  5. Samiei, H., B. Sadighi-Moghaddam, S. Mohammadi, A. Gharavi and S. Abdolmaleki et al., 2019. Dysregulation of helper T lymphocytes in esophageal squamous cell carcinoma (ESCC) patients is highly associated with aberrant production of miR-21. Immunol. Res., 67: 212-222.
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  6. Mohammadi, S., S. Sedighi and A. Memarian, 2019. IL-17 is aberrantly overexpressed among under-treatment systemic lupus erythematosus patients. Iran J. Pathol., 14: 236-242.
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  7. Memarian, A., H. Samiei, B. Sedighi-Moghaddam, S. Mohammadi, A. Gharavi, S. Abdolmaleki and M. Jeddi-Tehrani, 2019. Dysregulation of helper T lymphocytes in esophageal squamous cell carcinoma (ESCC) patients is highly associated with aberrant production of miR-21. Annals. Oncol., 10.1093/annonc/mdz268.029.
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  8. Hasani, M., N.A. Sani, B. Khodabakhshi, M.S. Arabi, S. Mohammadi and Y. Yazdani, 2019. Encapsulation of Leflunomide (LFD) in a novel niosomal formulation facilitated its delivery to THP-1 monocytic cells and enhanced Aryl hydrocarbon receptor (AhR) nuclear translocation and activation. DARU J. Pharm. Sci., 27: 635-644.
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  9. Emampanahi, M., Saba Masoudi Rad, Marie S. Jazi, N.M. Samaei, N. Behnampour, S. Mohammadi and E. Fakhari, 2019. Association between interleukin‐10 gene polymorphisms and severe chronic periodontitis. Oral Dis., 25: 1619-1626.
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  10. Ajam, F., M. Aghaei, S. Mohammadi, M. Saeedi, N. Behnampour and A. Memarian, 2019. Increased expression of PD-1 on CD4+ T cells subsets in Rheumatoid Arthritis patients. Jorjani Biomed. J., 7: 61-70.
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  11. Mohammadi, S., M.S. Jazi, M.Z. Ebrahimabad, F. Eghbalpour, N. Abdolahi, A. Tabarraei and Y. Yazdani, 2018. Interleukin 10 gene promoter polymorphisms (rs1800896, rs1800871 and rs1800872) and haplotypes are associated with the activity of systemic lupus erythematosus and IL10 levels in an Iranian population. Int. J. Immunogenet., 46: 20-30.
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  12. Mohammadi, S., M. Saghaeian-Jazi, S. Sedighi and A. Memarian, 2018. Sodium valproate modulates immune response by alternative activation of monocyte-derived macrophages in systemic lupus erythematosus. Clin. Rheumatol., 37: 719-727.
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  13. Mohammadi, S., A. Memarian, S. Sedighi, N. Behnampour and Y. Yazdani, 2018. Immunoregulatory effects of indole-3-carbinol on monocyte-derived macrophages in systemic lupus erythematosus: A crucial role for aryl hydrocarbon receptor. Autoimmunity, 51: 199-209.
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  14. Mohammadi, S., S. Sedighi, A. Memarian and Y. Yazdani, 2017. Overexpression of interferon-γ and indoleamine 2, 3-dioxygenase in systemic lupus erythematosus: Relationship with the disease activity. Laboratoriums Med., 41: 41-47.
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  15. Mohammadi, S., M.R. Ebadpour, S. Sedighi, M. Saeedi and A. Memarian, 2017. Glucocorticoid-induced leucine zipper expression is associated with response to treatment and immunoregulation in systemic lupus erythematosus. Clin. Rheumatol., 36: 1765-1772.
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  16. Mohammadi, S., M. Saghaeian-Jazi, S. Sedighi and A. Memarian, 2017. Immunomodulation in systemic lupus erythematosus: Induction of M2 population in monocyte-derived macrophages by pioglitazone. Lupus, 26: 1318-1327.
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  17. Mohammadi, S., F.S. Seyedhosseini, N. Behnampour and Y. Yazdani, 2017. Indole-3-carbinol induces G1 cell cycle arrest and apoptosis through aryl hydrocarbon receptor in THP-1 monocytic cell line. J. Recept. Signal Transduction, 37: 506-514.
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  18. Mohammadi, S., F.S. Seyedhoseini, J. Asadi and Y. Yazdani, 2017. Effects of berberine on the secretion of cytokines and expression of genes involved in cell cycle regulation in THP-1 monocytic cell line. Iran. J. basic med. Sci., 20: 530-537.
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  19. Mohebbi, A., S. Mohammadi and A. Memarian, 2016. Prediction of HBF-0259 interactions with hepatitis B virus receptors and surface antigen secretory factors. Virus Dis., 27: 234-241.
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  20. Jazi, M.S. and S. Mohammadi, 2016. Culture and differentiation of monocyte derived macrophages using human serum: An optimized method. Zahedan J. Res. Med. Sci., 18: 29-32.
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  21. . Jazi, M.S., S. Mohammadi, Y. Yazdani, S. Sedighi, A. Memarian and M. Aghaei, 2016. Effects of valproic acid and pioglitazone on cell cycle progression and proliferation of T-cell acute lymphoblastic leukemia Jurkat cells. Iran. J. basic med. Sci., 19: 779-786.
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  22. Yazdani, Y., S. Mohammadi, M. Yousefi and F. Shokri, 2015. Preliminary assessment of various additives on the specific reactivity of anti-rHBsAg monoclonal antibodies. Avicenna J. Med. Biotechnol., 7: 145-150.
    PubMed  |  
  23. Sadeghian, H., S. Saedi, A. Sadeghian, M. Akhlaghi, S. Mohammadi and H. Safdari, 2015. Epidemiology and the agreement rate of serological tests in human brucellosis in north east of Iran. Arch. Clin. Infect. Dis., Vol. 10. 10.5812/archcid.10(2)2015.20239.
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  24. Namdar, F., A. Ebrahimzadeh and S. Mohammadi, 2014. Allelic variation of polymorphic vaccine candidates merozoite surface protein-2 in plasmodium falciparum isolates from south-east of Iran. Adv. Environ. Biol., 8: 155-158.
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  25. Jamshidi, A., M.M. Ghahfarrokhi, A. Gharaei, A. Ebrahimzadeh, M.J. Modrek, A.A. Moghadam and S. Mohammadi, 2014. Genotyping of C and F regions of plasmodium falciparum EBA-175 in south-east of Iran. Med. Lab. J., 8: 36-41.
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  26. Ebrahimzadeh, A., S. Mohammadi, M. Polshekan, A. Jamshidi and A. Mehravaran, 2014. Evaluation of negative malaria giemsa-stained smears referred from malaria centers in Sistan and Balouchestan using nested polymerase chain reaction. Zahedan J. Res. Med. Sci., 16: 15-18.
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  27. Ebrahimzadeh, A., S. Mohammadi, A. Salimi-Khorashad and A. Jamshidi, 2014. Seroprevalence of human cystic echinococcosis in Zahedan, Iran. Zahedan J. Res. Med. Sci., 16: 48-48‎.
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  28. Ebrahimzadeh, A., S. Mohammadi and A. Jamshidi, 2014. Allelic forms of merozoite surface protein-3 in Plasmodium falciparum isolates from southeast of Iran. Jundishapur J. Microbiol., Vol. 7. 10.5812/jjm.9829.
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  29. Adel, E., M. Saeed and P.M. Ali, 2014. Nested polymerase chain reaction (PCR) on fixed stained slides in comparison to whole blood as a source of DNA in southeast of Iran. J. Trop. Dis. Public Health, Vol. 2. 10.4172/2329-891X.1000136.
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  30. . Ebrahimzadeh, A., S. Mohammadi and A. Jamshidi, 2014. Allelic forms of merozoite surface protein-3 in Plasmodium falciparum isolates from Southeast of Iran. Jundishapur j. Microbial., Vol. 7. 10.5812/jjm.9829.
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  31. Ebrahimzadeh, A., S. Mohammadi, A. Salimi-Khorashad and A. Jamshidi, 2013. Seroprevalence of toxoplasmosis among pregnant women referring to the reference laboratory of Zahedan, Iran. Zahedan J. Res. Med. Sci., 15: 32-35.
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  32. Ebrahimzadeh, A., A. Jamshidi and S. Mohammadi, 2013. The parasitic contamination of raw vegetables consumed in Zahedan, Iran. Health Scope, 1: 205-209.
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  33. Jamshidi, A., S. Mohammadi and A. Mohammadi, 2011. Quantification of Escherichia coli O157: H7 in milk by most probable number-polymerase chain reaction (MPN-PCR) method. Afr. J. Microbiol. Res., 5: 4588-4591.
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  34. Derakhshan, M., H. Safdari, A. Sadeghi, K. Ghazvini and S. Mohammadi, 2009. Prevalence of mycobacterium tuberculosis in the samples referred to the tuberculosis research laboratory in Mashhad Ghaem Hospital during 2005-2006. Iran. J. Microbiol., 1: 20-22.
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